Abstract
The combination of various reactions in one operational step leads to many advantages in synthetic strategies, such as a lower consumption of resources, effort, arid time, when intermittent workup and purification steps can be avoided. The hydroformylation reaction of acrylates gives access to 2-formylpropanoates, which thanks to their structural features constitute useful intermediates in the ...
Abstract
The combination of various reactions in one operational step leads to many advantages in synthetic strategies, such as a lower consumption of resources, effort, arid time, when intermittent workup and purification steps can be avoided. The hydroformylation reaction of acrylates gives access to 2-formylpropanoates, which thanks to their structural features constitute useful intermediates in the synthesis of more complex compounds. Herein, we report a simple arid convenient one-pot strategy to synthesize functionalized carbonyl, compounds starting from these readily available substrates, via tandem or one-pot hydroformylation, Michael addition, and aldol reactions,
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