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Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients

Johannesen, Siw Wollebæk (2019) Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients. PhD, Universität Regensburg.

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Date of publication of this fulltext: 02 May 2019 12:51

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Other URL: https://www.frontiersin.org/articles/10.3389/fneur.2018.00971/full

Abstract (English)

Objective: To evaluate safety, tolerability and feasibility of long-term treatment with Granulocyte-colony stimulating factor (G-CSF), a well-known hematopoietic stem cell factor, guided by assessment of mobilized bone marrow derived stem cells and cytokines in the serum of patients with amyotrophic lateral sclerosis (ALS) treated on a named patient basis. Methods: 36 ALS patients were ...


Translation of the abstract (German)

Fragestellungen: Die vorliegende Arbeit umfasst retrospektive Analysen experimenteller Langzeitbehandlungen mit G-CSF, ein gut bekannter Wachstumsfaktor hämatopoetischer Stammzellen, bei ALS-Patienten und untersucht den möglichen Einsatz hämatopoetischer Stammzellen und unterschiedlicher Zytokine bei diesen individuellen experimentalen Therapieversuchen. Methoden: 36 ALS-Patienten wurden ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:2 May 2019
Referee:Prof. Dr. Ulrich Bogdahn
Date of exam:12 April 2019
Institutions:Medicine > Lehrstuhl für Neurologie
Identification Number:
Keywords:ALS, G-CSF, Biomarker
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40110
Owner only: item control page


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