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Prospect of Plasmacytoid Dendritic Cells in Enhancing Anti-Tumor Immunity of Oncolytic Herpes Viruses

Schuster, Philipp, Lindner, Georg, Thomann, Sabrina, Haferkamp, Sebastian and Schmidt, Barbara (2019) Prospect of Plasmacytoid Dendritic Cells in Enhancing Anti-Tumor Immunity of Oncolytic Herpes Viruses. Cancers 11 (5), p. 651.

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Date of publication of this fulltext: 04 Jul 2019 04:43

at publisher (via DOI)

Other URL: http://doi.org/10.3390/cancers11050651


Abstract

The major type I interferon-producing plasmacytoid dendritic cells (pDC) surround and infiltrate certain tumors like malignant melanoma, head and neck cancer, and ovarian and breast cancer. The presence of pDC in these tumors is associated with an unfavorable prognosis for the patients as long as these cells are unstimulated. Upon activation by synthetic Toll-like receptor agonists or viruses, ...

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Item type:Article
Date:11 May 2019
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/cancers11050651DOI
Keywords:plasmacytoid dendritic cells; herpes simplex virus 1; oncolytic virus
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40450
Owner only: item control page

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