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Dynamics of Renal Electrolyte Excretion in Growing Mice

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Schmidt, Katharina ; Ripper, Maria ; Tegtmeier, Ines ; Humberg, Evelyn ; Sterner, Christina ; Reichold, Markus ; Warth, Richard ; Bandulik, Sascha
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Date of publication of this fulltext: 09 Oct 2019 12:05


Genetically modified mice represent important models for elucidating renal pathophysiology, but gene deletions frequently cause severe failure to thrive. In such cases, the analysis of the phenotype is often limited to the first weeks of life when renal excretory function undergoes dramatic physiological changes. Here, we investigated the postnatal dynamics of urinary ion excretion in mice. The ...


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