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Low Endotoxin Recovery—Masking of Naturally
Occurring Endotoxin

URN to cite this document:
urn:nbn:de:bvb:355-epub-415394
Reich, Johannes ; Weyer, Felix A. ; Tamura, Hiroshi ; Nagaoka, Isao ; Motschmann, Hubert
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 10 Feb 2020 14:31



Abstract

Endotoxins are cell wall components of Gram-negative bacteria. A release of endotoxins into the human blood stream results in an inflammation reaction that can lead to life-threatening conditions like sepsis. Therefore, control for endotoxin contamination of intravenously administered drugs is crucial. Drugs are usually tested for putative endotoxin contamination with Limulus-based tests. ...

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