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The effect of leukocyte-reduced platelet-rich plasma on the proliferation of autologous adipose-tissue derived mesenchymal stem cells1

Loibl, Markus ; Lang, Siegmund ; Brockhoff, Gero ; Gueorguiev, Boyko ; Hilber, Franz ; Worlicek, Michael ; Baumann, Florian ; Grechenig, Stephan ; Zellner, Johannes ; Huber, Michaela ; Valderrabano, Victor ; Angele, Peter ; Nerlich, Michael ; Prantl, Lukas ; Gehmert, Sebastian



Abstract

Clinical application of platelet-rich plasma (PRP) and stem cells has become more and more important in regenerative medicine during the last decade. However, differences in PRP preparations may contribute to variable PRP compositions with unpredictable effects on a cellular level. In the present study, we modified the centrifugation settings in order to provide a leukocyte-reduced PRP and ...

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