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Analysing data from patient-reported outcome and quality of life endpoints for cancer clinical trials: a start in setting international standards

Bottomley, Andrew ; Pe, Madeline ; Sloan, Jeff ; Basch, Ethan ; Bonnetain, Franck ; Calvert, Melanie ; Campbell, Alicyn ; Cleeland, Charles ; Cocks, Kim ; Collette, Laurence ; Dueck, Amylou C. ; Devlin, Nancy ; Flechtner, Hans-Henning ; Gotay, Carolyn ; Greimel, Eva ; Griebsch, Ingolf ; Groenvold, Mogens ; Hamel, Jean-Francois ; King, Madeleine ; Kluetz, Paul G. ; Koller, Michael ; Malone, Daniel C. ; Martinelli, Francesca ; Mitchell, Sandra A. ; Moinpour, Carol M. ; Musoro, Jammbe ; O’Connor, Daniel ; Oliver, Kathy ; Piault-Louis, Elisabeth ; Piccart, Martine ; Pimentel, Francisco L. ; Quinten, Chantal ; Reijneveld, Jaap C. ; Schürmann, Christoph ; Smith, Ashley Wilder ; Soltys, Katherine M. ; Taphoorn, Martin J. B. ; Velikova, Galina ; Coens, Corneel



Abstract

Measures of health-related quality of life (HRQOL) and other patient-reported outcomes generate important data in cancer randomised trials to assist in assessing the risks and benefits of cancer therapies and fostering patient-centred cancer care. However, the various ways these measures are analysed and interpreted make it difficult to compare results across trials, and hinders the application ...

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