Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity

URN to cite this document:: urn:nbn:de:bvb:355-epub-440867
DOI to cite this document:: 10.5283/epub.44086

Müller, Max

; Egger, Veronica

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Date of publication of this fulltext: 13 Jan 2021 10:54

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Abstract

The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition. As a case in point for dendritic transmitter release, rat granule cell dendrites are highly excitable, featuring local Na(+)spine spikes and global Ca2+- and Na+-spikes. To investigate the transition from local to ...