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RNA-Binding Protein La Mediates TGFβ-Induced Epithelial to Mesenchymal Transition and Cancer Stem Cell Properties

URN to cite this document:
urn:nbn:de:bvb:355-epub-444089
DOI to cite this document:
10.5283/epub.44408
Sommer, Gunhild ; Heise, Tilman
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 11 Feb 2021 16:25



Abstract

Simple Summary Reversible epithelial to mesenchymal transition (EMT) plays a key role in establishing a malignant phenotype by assuring cancer cell plasticity critical for cancer progression by allowing a small fraction of cancer cells to detach from primary lesions and outgrow at metastatic sites. Cancer cell plasticity is associated with cancer stem cell properties contributing to ...

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