Dietary Salt Accelerates Orthodontic Tooth Movement by Increased Osteoclast Activity

URN to cite this document:: urn:nbn:de:bvb:355-epub-444108
DOI to cite this document:: 10.5283/epub.44410

Schröder, Agnes

; Gubernator, Joshua ; Leikam, Alexandra ; Nazet, Ute

; Cieplik, Fabian

; Jantsch, Jonathan ; Neubert, Patrick ; Titze, Jens ; Proff, Peter ; Kirschneck, Christian

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Date of publication of this fulltext: 12 Jan 2021 11:58

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Abstract

Dietary salt uptake and inflammation promote sodium accumulation in tissues, thereby modulating cells like macrophages and fibroblasts. Previous studies showed salt effects on periodontal ligament fibroblasts and on bone metabolism by expression of nuclear factor of activated T-cells-5 (NFAT-5). Here, we investigated the impact of salt and NFAT-5 on osteoclast activity and orthodontic tooth ...