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Reduced store-operated Ca2+ entry impairs mesenteric artery function in response to high external glucose in type 2 diabetic ZDF rats

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Schach, Christian ; Wester, Michael ; Leibl, Florian ; Redel, Andreas ; Gruber, Michael ; Maier, Lars S. ; Endemann, Dierk ; Wagner, Stefan
License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 01 Feb 2021 10:25

This publication is part of the DEAL contract with Wiley.


Diabetes is a major risk factor for cardiovascular disease, affecting both endothelial and smooth muscle cells. Store-operated Ca2+ channels (SOCCs) have been implicated in many diabetic complications. Vascular dysfunction is common in patients with diabetes, but the role of SOCCs in diabetic vasculopathy is still unclear. Our research aimed to investigate the effects of high glucose (HG) on ...


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