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A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology

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Lorenz, Julia ; Rothhammer-Hampl, Tanja ; Zoubaa, Saida ; Bumes, Elisabeth ; Pukrop, Tobias ; Kölbl, Oliver ; Corbacioglu, Selim ; Schmidt, Nils O. ; Proescholdt, Martin A. ; Hau, Peter ; Riemenschneider, Markus J.
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 19 Feb 2021 11:30


Recent updates in the classification of central nervous system (CNS) tumors have increased the need for molecular testing. Assessment of multiple alterations in parallel, complex combinations of gene sequence and chromosomal changes, as well as therapy prediction by identification of actionable mutations are the major challenges. We here report on a customized next generation sequencing ...


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