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Photosensitized direct C–H fluorination and trifluoromethylation in organic synthesis

Yakubov, Shahboz ; Barham, Joshua P



Abstract

The importance of fluorinated products in pharmaceutical and medicinal chemistry has necessitated the development of synthetic fluorination methods, of which direct C-H fluorination is among the most powerful. Despite the challenges and limitations associated with the direct fluorination of unactivated C-H bonds, appreciable advancements in manipulating the selectivity and reactivity have been ...

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