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Benefit of adjuvant chemotherapy in high-risk colon cancer: A 17-year population-based analysis of 6131 patients with Union for International Cancer Control stage II T4N0M0 colon cancer

Teufel, Andreas ; Gerken, Michael ; Fürst, Alois ; Ebert, Matthias ; Hohenthanner, Ina ; Klinkhammer-Schalke, Monika


Background: The benefit of adjuvant chemotherapy in Union for International Cancer Control (UICC) stage III colon cancer has been demonstrated in numerous studies. While adjuvant chemotherapy is generally not recommended in stage II patients, its role in high-risk UICC stage II disease (e.g. T4 tumours) remains controversial. Methods: The present population-based multicenter cohort study ...


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