Granulocyte transfusions made with modified fluid gelatin in pediatric and adolescent patients with prolonged neutropenia

URN to cite this document:: urn:nbn:de:bvb:355-epub-512611
DOI to cite this document:: 10.5283/epub.51261

Knapp, Selina ; Brosig, Andreas ; Troeger, Anja ; Kleinschmidt, Katharina ; Offner, Robert ; Corbacioglu, Selim ; Burkhardt, Ralph

; Foell, Juergen ; Ahrens, Norbert

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Date of publication of this fulltext: 23 Dec 2021 08:28

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Abstract

Background Granulocyte transfusions (GT) are used to treat progressive systemic or local infections in prolonged neutropenic patients with antibiotic or antifungal resistance. Granulocytes are most commonly collected from whole blood by apheresis using hydroxyethyl starch (HES) as the red blood cell (RBC) sedimentation agent. This is the first study on the safety and efficacy of transfusing ...