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Granulocyte transfusions made with modified fluid gelatin in pediatric and adolescent patients with prolonged neutropenia

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Knapp, Selina ; Brosig, Andreas ; Troeger, Anja ; Kleinschmidt, Katharina ; Offner, Robert ; Corbacioglu, Selim ; Burkhardt, Ralph ; Foell, Juergen ; Ahrens, Norbert
License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 23 Dec 2021 08:28

This publication is part of the DEAL contract with Wiley.


Background Granulocyte transfusions (GT) are used to treat progressive systemic or local infections in prolonged neutropenic patients with antibiotic or antifungal resistance. Granulocytes are most commonly collected from whole blood by apheresis using hydroxyethyl starch (HES) as the red blood cell (RBC) sedimentation agent. This is the first study on the safety and efficacy of transfusing ...


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