Massive haemolysis after intramuscular diclofenac in a patient who apparently tolerated oral medication

DOI to cite this document:: 10.5283/epub.51263

Ahrens, Norbert

; Schewior, L. ; Garbe, E. ; Kiesewetter, H. ; Salama, A.

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Date of publication of this fulltext: 22 Dec 2021 10:00

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Abstract

Background and Objectives Administration of diclofenac may lead to immune haemolytic anaemia (IHA) owing to the presence of drug-dependent antibodies and/or autoantibodies. A relationship with oral or intramuscular drug administration is unknown. Here, we describe a patient who apparently tolerated oral diclofenac but developed severe IHA following intramuscular injection of the ...