Go to content
UR Home

Extracellular citrate and metabolic adaptations of cancer cells

URN to cite this document:
DOI to cite this document:
Parkinson, E. Kenneth ; Adamski, Jerzy ; Zahn, Grit ; Gaumann, Andreas ; Flores-Borja, Fabian ; Ziegler, Christine ; Mycielska, Maria E.
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 23 Dec 2021 08:34


It is well established that cancer cells acquire energy via the Warburg effect and oxidative phosphorylation. Citrate is considered to play a crucial role in cancer metabolism by virtue of its production in the reverse Krebs cycle from glutamine. Here, we review the evidence that extracellular citrate is one of the key metabolites of the metabolic pathways present in cancer cells. We review the ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 4239

Dissertations: dissertationen@ur.de
0941 943 3904

Research data: daten@ur.de
0941 943 4239

Contact persons