Assigning Co-Regulated Human Genes and Regulatory Gene Clusters

URN to cite this document:: urn:nbn:de:bvb:355-epub-514004
DOI to cite this document:: 10.5283/epub.51400

Strunz, Tobias

; Kellner, Martin

; Kiel, Christina

; Weber, Bernhard H. F.

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Date of publication of this fulltext: 12 Jan 2022 11:55

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Abstract

Elucidating the role of genetic variation in the regulation of gene expression is key to understanding the pathobiology of complex diseases which, in consequence, is crucial in devising targeted treatment options. Expression quantitative trait locus (eQTL) analysis correlates a genetic variant with the strength of gene expression, thus defining thousands of regulated genes in a multitude of human ...