A Systematic Review and Meta-Analysis of Studies of Defibrotide Prophylaxis for Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome

URN to cite this document:: urn:nbn:de:bvb:355-epub-523146
DOI to cite this document:: 10.5283/epub.52314

Corbacioglu, Selim ; Topaloglu, Ozlem ; Aggarwal, Saurabh

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Date of publication of this fulltext: 25 May 2022 04:38

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Abstract

Background and Objectives Defibrotide is approved to treat severe veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) after haematopoietic cell transplantation in patients aged > 1 month in the European Union and for VOD/SOS with renal/pulmonary dysfunction post-haematopoietic cell transplantation in the United States. This meta-analysis estimated the incidence and risk of VOD/SOS ...