Drug Repurposing by Tumor Tissue Editing

URN to cite this document:: urn:nbn:de:bvb:355-epub-526065
DOI to cite this document:: 10.5283/epub.52606

Lüke, Florian

; Harrer, Dennis Christoph ; Pantziarka, Pan

; Pukrop, Tobias

; Ghibelli, Lina ; Gerner, Christopher

; Reichle, Albrecht

; Heudobler, Daniel

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Date of publication of this fulltext: 14 Jul 2022 08:11

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Abstract

The combinatory use of drugs for systemic cancer therapy commonly aims at the direct elimination of tumor cells through induction of apoptosis. An alternative approach becomes the focus of attention if biological changes in tumor tissues following combinatory administration of regulatorily active drugs are considered as a therapeutic aim, e.g., differentiation, transdifferentiation induction, ...