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Hintschich, Constantin A. ; Fischer, René ; Hummel, Thomas ; Wenzel, Jürgen J. ; Bohr, Christopher ; Vielsmeier, Veronika

Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection

Article

Hintschich, Constantin A. , Fischer, René, Hummel, Thomas, Wenzel, Jürgen J. , Bohr, Christopher and Vielsmeier, Veronika (2022) Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection. PLOS ONE 17 (3), e02656866.

DOI to cite this document: 10.5283/epub.52935


Abstract

Olfactory and gustatory disorders are prominent symptoms of acute COVID-19. Although both senses recover in many patients within weeks to months, persistency has been described in up to 60%. However up to now most reports on the course of chemosensitive disorders after COVID-19 are not based on psychophysical testing but only on subjective patients' ratings. In this study we assessed both ...

Olfactory and gustatory disorders are prominent symptoms of acute COVID-19. Although both senses recover in many patients within weeks to months, persistency has been described in up to 60%. However up to now most reports on the course of chemosensitive disorders after COVID-19 are not based on psychophysical testing but only on subjective patients' ratings. In this study we assessed both olfaction and gustation using psychophysical tests eight months after COVID-19. Validated psychophysical testing revealed hyposmia in 18% and hypogeusia in even 32% of 303 included patients. This shows that olfactory and especially gustatory disorders have to be seen as important chronic symptoms post-COVID-19. The high prevalence of gustatory dysfunction indicates that gustatory function does not recover or might even deteriorate in the months following the acute infection.



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Details

Item typeArticle
Journal or Publication TitlePLOS ONE
PublisherPLOS
Open Access TypeGold (with APC)
Place of PublicationSAN FRANCISCO
Volume17
Number of Issue or Book Chapter3
Page Rangee02656866
Date23 March 2022
Date of publication29 Sep 2022 06:35
InstitutionsMedicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number
ValueType
10.1371/journal.pone.0265686DOI
KeywordsCHEMICAL SENSES; TASTE; COVID-19; SMELL;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgPartially
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-529358
Item ID52935

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