Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping

URN to cite this document:: urn:nbn:de:bvb:355-epub-530951
DOI to cite this document:: 10.5283/epub.53095

Jurek, Benjamin

; Denk, Lucia ; Schäfer, Nicole ; Salehi, Mohammad Saied

; Pandamooz, Sareh ; Haerteis, Silke

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 21 Oct 2022 17:41

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Abstract

Oxytocin (OXT) is a neuropeptide that has been associated with neurological diseases like autism, a strong regulating activity on anxiety and stress-related behavior, physiological effects during pregnancy and parenting, and various cellular effects in neoplastic tissue. In this study, we aimed to unravel the underlying mechanism that OXT employs to regulate cell-cell contacts, spheroid ...