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The effects of nitric oxide on coagulation and inflammation in ex vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

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Malfertheiner, Maximilian V. ; Garrett, Ashlen ; Passmore, Margaret ; Haymet, Andrew B. ; Webb, Richard I. ; Von Bahr, Viktor ; Millar, Jonathan E. ; Schneider, Bailey A. ; Obonyo, Nchafatso G. ; Black, Debra ; Bouquet, Mahe ; Bartnikowski, Nicole ; Suen, Jacky Y. ; Fraser, John F.
Date of publication of this fulltext: 25 Jul 2023 07:44

This publication is part of the DEAL contract with Wiley.


Background Extracorporeal life support (ECLS) has extensive applications in managing patients with acute cardiac and pulmonary failure. Two primary modalities of ECLS, cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), include several similarities in their composition, complications, and patient outcomes. Both CPB and ECMO pose a high risk of thrombus formation and ...


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