Reg3α concentrations at day of allogeneic stem cell transplantation predict outcome and correlate with early antibiotic use

URN to cite this document:: urn:nbn:de:bvb:355-epub-545168
DOI to cite this document:: 10.5283/epub.54516

Weber, Daniela ; Weber, Markus

; Meedt, Elisabeth ; Ghimire, Sakhila ; Wolff, Daniel

; Edinger, Matthias ; Poeck, Hendrik ; Hiergeist, Andreas

; Gessner, André

; Ayuk, Francis ; Roesler, Wolf ; Wölfl, Matthias ; Kraus, Sabrina ; Zeiser, Robert ; Bertrand, Hannah ; Bader, Peter ; Ullrich, Evelyn

; Eder, Matthias

; Gleich, Sigrun ; Young, Rachel ; Herr, Wolfgang ; Levine, John E. ; Ferrara, James L. M. ; Holler, Ernst

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Date of publication of this fulltext: 24 Jul 2023 07:20

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Abstract

Intestinal microbiome diversity plays an important role in the pathophysiology of acute gastrointestinal (GI) graft-versus-host disease (GVHD) and influences the outcome of patients after allogeneic stem cell transplantation (ASCT). We analyzed clinical data and blood samples taken preconditioning and on the day of ASCT from 587 patients from 7 German centers of the Mount Sinai Acute GVHD ...