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Interprofessional Therapeutic Drug Monitoring of Carbapenems Improves ICU Care and Guideline Adherence in Acute-on-Chronic Liver Failure

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Schmid, Stephan ; Koch, ChiarA ; Zimmermann, Katharina ; Buttenschoen, Jonas ; Mehrl, Alexander ; Pavel, Vlad ; Schlosser-Hupf, Sophie ; Fleischmann, Daniel ; Krohn, Alexander ; Schilling, Tobias ; Müller, Martina ; Kratzer, Alexander
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Date of publication of this fulltext: 21 Dec 2023 13:19


(1) Background: Acute-on-chronic liver failure (ACLF) is a severe, rapidly progressing disease in patients with liver cirrhosis. Meropenem is crucial for treating severe infections. Therapeutic drug monitoring (TDM) offers an effective means to control drug dosages, especially vital for bactericidal antibiotics like meropenem. We aimed to assess the outcomes of implementing TDM for meropenem ...


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