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Synthesis of biologically active guaianolides with a trans-annulated lactone moiety

Schall, A. and Reiser, O. (2008) Synthesis of biologically active guaianolides with a trans-annulated lactone moiety. European Journal of Organic Chemistry (14), pp. 2353-2364.

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The biosynthetic pathways of sesquiterpene lactones are described in conjunction with recent developments in the total syntheses of various biologically active guaianolides. Different strategies towards the 5,7,5-membered ring system are highlighted. Oxidative diol cleavages, aldol reactions, and intramolecular cyclopropanations were used as key reactions to construct the racemic guaianolide core ...


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Item type:Article
Additional Information (public):Schall, Andreas; Reiser, Oliver
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Identification Number:
ISI:000256233400001Web of Science ID
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:5718
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