Collagen sandwich culture affects intracellular polyamine levels of human hepatocytes

URN to cite this document:: urn:nbn:de:bvb:355-epub-589931
DOI to cite this document:: 10.5283/epub.58993

Weiss, Thomas S.

; Jahn, B. ; Cetto, M. ; Jauch, K. W. ; Thasler, W. E.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Aug 2024 07:15

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Abstract

Abstract Extracellular matrices, like collagen layers, play an important role in preventing dedifferentiation of hepatocytes in long-term culture experiments. It has also been shown that polyamines are crucial for cell growth and liver differentiation – regeneration. Primary cultured hepatocytes with their low mitotic activity might be a valuable tool in studying the role of polyamines in ...