Proprotein Convertase Subtilisin/Kexin Type 9 Induction in COVID-19 Is Poorly Associated with Disease Severity and Cholesterol Levels

URN to cite this document:: urn:nbn:de:bvb:355-epub-590407
DOI to cite this document:: 10.5283/epub.59040

Mester, Patricia ; Amend, Pablo ; Schmid, Stephan

; Wenzel, Jürgen J.

; Höring, Marcus

; Liebisch, Gerhard

; Krautbauer, Sabrina ; Müller, Martina ; Buechler, Christa

; Pavel, Vlad

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 03 Sep 2024 08:02

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Abstract

SARS-CoV-2 infection was shown to induce proprotein convertase subtilisin/kexin type 9 (PCSK9) plasma levels in sepsis. Here, we investigate the association between serum PCSK9 levels and disease severity. PCSK9 was measured in serum of 55 controls, 40 patients with moderate and 60 patients with severe COVID-19 disease. Serum PCSK9 was elevated in moderate COVID-19 compared to controls and ...