Rapid quantification of murine bile acids using liquid chromatography-tandem mass spectrometry

URN to cite this document:: urn:nbn:de:bvb:355-epub-597188
DOI to cite this document:: 10.5283/epub.59718

Hermeling, Sven ; Plagge, Johannes

; Krautbauer, Sabrina ; Ecker, Josef

; Burkhardt, Ralph

; Liebisch, Gerhard

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 02 Dec 2024 09:57

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Abstract

Interest in bile acids (BAs) is growing due to their emerging role as signaling molecules and their association with various diseases such as colon cancer and metabolic syndrome. Analyzing BAs requires chromatographic separation of isomers, often with long run times, which hinders BA analysis in large studies. Here, we present a high-throughput method based on liquid chromatography-tandem mass ...