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Clinical Outcome and Quality of Life of Multimodal Treatment of Extracranial Arteriovenous Malformations: The APOLLON Study Protocol

Schmidt, Vanessa F. ; Masthoff, Max ; Vielsmeier, Veronika ; Seebauer, Caroline T. ; Cangir, Özlem ; Meyer, Lutz ; Mükke, Antje ; Lang, Werner ; Schmid, Axel ; Sporns, Peter B. ; Brill, Richard ; Wohlgemuth, Walter A. ; da Silva, Natascha Platz Batista ; Seidensticker, Max ; Schinner, Regina ; Küppers, Julia ; Häberle, Beate ; Haubner, Frank ; Ricke, Jens ; Zenker, Martin ; Kimm, Melanie A. ; Wildgruber, Moritz



Abstract

Purpose Arteriovenous malformations (AVMs) as rare diseases are diagnostically and therapeutically challenging. Due to the limited evidence regarding treatment outcome, prospective data are needed on how different treatment regimens affect outcome. The aims of this prospective trial are to determine effectiveness, safety, and clinical outcome of multimodal treatment in patients with extracranial ...

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