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Updating the probability of study success for combination therapies using related combination study data

URN to cite this document:
urn:nbn:de:bvb:355-epub-758684
DOI to cite this document:
10.5283/epub.75868
Graham, Emily ; Harbron, Chris ; Jaki, Thomas
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
(1MB)
Date of publication of this fulltext: 18 Mar 2025 10:06



Abstract

Combination therapies are becoming increasingly used in a range of therapeutic areas such as oncology and infectious diseases, providing potential benefits such as minimising drug resistance and toxicity. Sets of combination studies may be related, for example, if they have at least one treatment in common and are used in the same indication. In this setting, value can be gained by sharing ...

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