Therapeutic drug monitoring of piperacillin: Agreement between quantitative nuclear magnetic resonance spectroscopy and liquid chromatography with tandem mass spectrometry

URN to cite this document:: urn:nbn:de:bvb:355-epub-771572
DOI to cite this document:: 10.5283/epub.77157

Dejaco, Alexander

; Paal, Michael ; Gruber, Michael

; Drettwan, Diana ; Marquardt, Christian ; Helou, Michael ; Wagner, Tobias ; Kees, Martin G.

; Graf, Bernhard M. ; Barthelmes, Dominic

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 16 Jul 2025 06:09

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Abstract

Background: In clinical practice, therapeutic drug monitoring (TDM) typically relies on specialized immunoassays or chromatography-based methods. These approaches require drug-specific setups and are limited to batch measurements, which can restrict their availability. Recent advances in quantitative nuclear magnetic resonance spectroscopy (qNMR) have made it suitable for rapid and reliable ...