Identification of the Centrifugation-Caused Paralytic Impact on Neutrophils

URN to cite this document:: urn:nbn:de:bvb:355-epub-777804
DOI to cite this document:: 10.5283/epub.77780

Pehl, Sophie ; Hundhammer, Tobias ; Rimboeck, Julia

; Kraus, Richard Felix

; Heckscher, Simon ; Kellermeier, Fabian ; Gruber, Michael

; Wittmann, Sigrid

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 18 Sep 2025 12:38

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Abstract

To investigate granulocytes under laboratory conditions, centrifugation steps are typically required for the isolation of neutrophil granulocytes from whole blood. However, only a few studies to date have addressed the direct effects of centrifugation itself on the functional state of neutrophils. This study aims to elucidate the mechanisms that contribute to the modification of granulocytes ...