Trägt Nikotin zur Krebsentstehung im oberen Aerodigestivtrakt bei?

DOI to cite this document:: 10.5283/epub.778

Kleinsasser, N. H. ; Sassen, A. W. ; Semmler, M. P. ; Staudenmaier, R. ; Harréus, U. A. ; Richter, E.

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Date of publication of this fulltext: 05 Aug 2009 13:24

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Abstract

It is accepted that nicotine in tobacco smoke causes addiction via nicotinic acetylcholine receptors in the central nervous system. For a long time, the tumorigenic potential of smoking was attributed to compounds other than nicotine. However, more recently data have accumulated which suggest that nicotine may add to the cancer risk by stimulating cellular growth via non-neuronal acetylcholine ...