Development of a Novel Homogeneous Liposome-Based One-Step Assay for SARS-CoV-2 Antibody Detection in Human Serum Based on Fluorescent Liposomes and Complement Activity

URN to cite this document:: urn:nbn:de:bvb:355-epub-781219
DOI to cite this document:: 10.5283/epub.78121

Reiner, Christina ; Hoecherl, Kilian ; Einhauser, Sebastian

; Streif, Simon

; Spitzenberg, Clemens

; Konrad, Johannes

; Neckermann, Patrick

; Breunig, Miriam

; Pauly, Diana

; Wagner, Ralf

; Baeumner, Antje J.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 10 Nov 2025 15:21

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Abstract

Monitoring antibodies in patient serum enables the diagnosis of infectious and chronic diseases, the assessment of an individual’s immune status, and possible protection against infection and could thus be a ubiquitous tool for pandemic preparedness and personalized medicine. Advancing from the traditional enzyme-linked immunosorbent assay (ELISA), a homogeneous assay format was developed that ...