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An improved diffusion/compartmental model for transdermal drug delivery from a matrix-type device

Göpferich, Achim and Lee, Geoffrey (1991) An improved diffusion/compartmental model for transdermal drug delivery from a matrix-type device. International Journal of Pharmaceutics 71 (3), pp. 237-243.

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Abstract

A mathematical model is presented for the description of transdermal drug delivery from a matrix-type delivery device. The model is partly diffusional and partly compartmental in nature. The matrix and stratum corneum are both considered to be diffusion layers, connected to a three-compartment model representing the viable epidermis/dermis, plasma, and peripheral tissues. The diffusion equation ...

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Item type:Article
Date:1991
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:TRANSDERMAL DRUG DELIVERY; POLYMER MATRIX; MODEL
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:8514
Owner only: item control page

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