Pollak, Nils (2005) Die Rolle von MIF (macrophage migration inhibitory factor) in der Sepsis-induzierten Immunparalyse. PhD, Universität Regensburg.
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Abstract (German)
Bei der Therapie der Sepsis durch Modulation des Immunsystems ist es von entscheidender Bedeutung, den genauen Immunstatus des Patienten zu kennen. Dies konnte auch im Tiermodell der Sepsis durch die Regulation des proinflammatorischen Proteins MIF nachgewiesen werden. So schützt die Neutralisation von MIF vor der Manifestation der Krankheit vor den Folgen eines septischen Schocks und verringert ...
Translation of the abstract (English)
Nosocomial infections in immune suppressed patients are a widespread problem in intensive care medicine. Such patients are highly susceptible to infections because their immune defenses are impaired and, therefore, unable to adequately combat invading microorganisms. To investigate the problem of sepsis-induced immune suppression we used a model in which mice developed sublethal peritonitis ...
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| Item type: | Thesis of the University of Regensburg (PhD) |
|---|---|
| Date: | 1 August 2005 |
| Referee: | Prof. Dr. Daniela Männel and Prof. Dr. Armin Buschauer |
| Date of exam: | 26 July 2005 |
| Institutions: | Medicine > Lehrstuhl für Immunologie Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) |
| Keywords: | Sepsis , Immunsuppression , Entzündung , Hospitalismus <Hygiene> , Tumor-Nekrose-Faktor , , sepsis , immunosuppression , inflammation , nosocomial infection , macrophage migration inhibitory factor |
| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences |
| Status: | Published |
| Refereed: | Yes, this version has been refereed |
| Created at the University of Regensburg: | Yes |
| Item ID: | 10332 |
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