Bibliography of the Universität Regensburg

University of Regensburg (619)
- Chemistry and Pharmacy (619)
  - Institute of Pharmacy (619)
    - Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) (619)

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Number of items at this level: 619.

2024

Scheuerer, Simon, Motlova, Lucia, Schäker-Hübner, Linda, Sellmer, Andreas, Feller, Felix, Ertl, Fabian J., Koch, Pierre

, Hansen, Finn K., Barinka, Cyril and Mahboobi, Siavosh

(2024) Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability. European Journal of Medicinal Chemistry 276, p. 116676.

Schindler, Lisa (2024) Development of stabilized NTS₁R and CXCR4 PET ligands using Nω-carbamoylated arginines for label attachment. PhD, Universität Regensburg.

2023

Tropmann, Katharina

(2023) A Step Forward to Unravel Open Histamine H2 Receptor Questions: Synthesis and Biological Evaluation of Novel H2R Ligands Including Radio- and Fluorescence-Labeled Pharmacological Tools. PhD, Universität Regensburg.

Höring, Carina

(2023) Split-Luciferase Complementation and Molecular Dynamics Studies for the Mini-G Protein-Based Functional Characterization of GPCRs. PhD, Universität Regensburg.

Wirth, Ulrike, Erl, Julia, Azzam, Saphia, Hoering, Carina, Skiba, Michael, Singh, Ritu, Hochmuth, Kathrin, Keller, Max

, Wegener, Joachim

and König, Burkhard

(2023) Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance Analysis. Angewandte Chemie International Edition, e202215547.

Grätz, Lukas (2023) Luminescence-based methods for the investigation of ligand binding and GRK2 recruitment to GPCRs. PhD, Universität Regensburg.

Hoffelner, Beate Sandra, Andreev, Stanislav

, Plank, Nicole and Koch, Pierre

(2023) Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells. Pharmaceuticals 16 (2), p. 264.

2022

Grätz, Lukas, Müller, Christoph, Pegoli, Andrea

, Schindler, Lisa, Bernhardt, Günther

and Littmann, Timo (2022) Insertion of Nanoluc into the Extracellular Loops as a Complementary Method To Establish BRET-Based Binding Assays for GPCRs. ACS Pharmacology & Translational Science 5 (11), pp. 1142-1155.

Andreev, Stanislav

, Plank, Nicole, Schollmeyer, Dieter and Koch, Pierre

(2022) (S)-3-(3-((7-Ethynyl-9H-pyrimido[4,5-b]indol-4-yl)amino)piperidin-1-yl)propanenitrile. Molbank 2022 (3), M1437.

Konieczny, Adam (2022) Design, Synthesis and Pharmacological Characterization of Oligopeptidic and Non-Peptidic Neuropeptide Y Y4 Receptor Ligands. PhD, Universität Regensburg.

Andreev, Stanislav, Pantsar, Tatu, Tesch, Roberta, Kahlke, Niclas, El-Gokha, Ahmed, Ansideri, Francesco, Grätz, Lukas, Romasco, Jenny, Sita, Giulia, Geibel, Christian

, Lämmerhofer, Michael, Tarozzi, Andrea, Knapp, Stefan

, Laufer, Stefan A. and Koch, Pierre

(2022) Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. Journal of Medicinal Chemistry 65 (2), pp. 1283-1301. Fulltext not available.

Katsouri, Ilektra Petrina, Vandervelpen, Ebert Vinciane G., Gattor, Albert Owusu, Engelbeen, Sarah, El Sayed, Abdulrahman, Seitaj, Klejdia, Becerra, Eduardo Daniel Morales and Vanderheyden, Patrick M.L. (2022) Complex FFA1 receptor (in)dependent modulation of calcium signaling by free fatty acids. Biochemical Pharmacology 202, p. 115150. Fulltext not available.

2021

Bartole, Edith

(2021) Design, Synthesis and Characterization of Molecular Tools for the Histamine H3 and H4 Receptors – In Particular Radio- and Fluorescent Ligands. PhD, Universität Regensburg.

Höring, Carina

, Conrad, Marcus, Söldner, Christian A.

, Wang, Jinan

, Sticht, Heinrich

, Strasser, Andrea and Miao, Yinglong (2021) Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations. International Journal of Molecular Sciences 22 (18), pp. 1-21.

Buschmann, Jonas (2021) Synthesis and pharmacological characterization of argininamide-type neuropeptide Y (NPY) Y1 and Y2 receptor antagonists and synthesis of non-peptide potential NPY Y4 receptor ligands. PhD, Universität Regensburg.

Weinhart, Corinna G.

(2021) Synthesis and pharmacological characterization of
dibenzodiazepinone-type muscarinic M2-receptor
antagonists conjugated to fluorescent dyes or
small peptides. PhD, Universität Regensburg.

Antoni, Frauke

(2021) Design, Synthesis and Characterization of ABCG2 Inhibitors with a Focus on Water Solubility and Stability in Plasma. PhD, Universität Regensburg.

Hoffmeister, Helen, Fuchs, Andreas

, Komives, Elizabeth, Groebner‐Ferreira, Regina, Strobl, Laura, Nazet, Julian, Heizinger, Leonhard, Merkl, Rainer, Dove, Stefan and Längst, Gernot (2021) Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability. The FEBS Journal 288, pp. 4000-4023.

Tropmann, Katharina, Bresinsky, Merlin, Forster, Lisa, Mönnich, Denise, Buschauer, Armin

, Wittmann, Hans-Joachim, Hübner, Harald, Gmeiner, Peter, Pockes, Steffen

and Strasser, Andrea

(2021) Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists. Journal of Medicinal Chemistry 64 (12), pp. 8684-8709. Fulltext not available.

Reynders, Martin, Chaikuad, Apirat, Berger, Benedict‐Tilman, Bauer, Katharina, Koch, Pierre

, Laufer, Stefan, Knapp, Stefan and Trauner, Dirk (2021) Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angewandte Chemie International Edition 60 (37), pp. 20178-20183. Fulltext not available.

Weinhart, Corinna. G., Wifling, David, Schmidt, Maximilian. F., Neu, Eduard, Höring, Carina, Clark, Timothy, Gmeiner, Peter and Keller, Max (2021) Dibenzodiazepinone-type muscarinic receptor antagonists conjugated to basic peptides: Impact of the linker moiety and unnatural amino acids on M2R selectivity. European Journal of Medicinal Chemistry 213, p. 113159. Fulltext not available.

Konieczny, Adam, Conrad, Marcus, Ertl, Fabian J., Gleixner, Jakob, Gattor, Albert O., Grätz, Lukas, Schmidt, Maximilian F., Neu, Eduard, Horn, Anselm H. C., Wifling, David, Gmeiner, Peter, Clark, Timothy, Sticht, Heinrich and Keller, Max (2021) N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y4 Receptor Ligands Results in Picomolar Binding Constants. Journal of Medicinal Chemistry 64 (22), pp. 16746-16769. Fulltext not available.

Biselli, Sabrina, Bresinsky, Merlin, Tropmann, Katharina, Forster, Lisa

, Honisch, Claudia

, Buschauer, Armin, Bernhardt, Günther and Pockes, Steffen

(2021) Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R. European Journal of Medicinal Chemistry 214, p. 113190. Fulltext not available.

Littmann, Timo, Ozawa, Takeaki and Bernhardt, Günther

(2021) 7. Quantitative Determination and Imaging of Gαq Signaling in Live Cells via Split-Luciferase Complementation. In: Kim, Dung-Bae, (ed.) Live Cell Imaging: Methods and Protocols. Methods in Molecular Biology, 2274 (7). Humana, Springer Science+Business Media, LLC, part of Springer Nature 2021, New York, pp. 69-78. ISBN 978-1-0716-1257-6. Fulltext not available.

Eitel, Michael

, Zinad, Dhafer S.

, Schollmeyer, Dieter, Gross, Harald

and Koch, Pierre (2021) Selective mono-de-O-acetylation of the per-O-acetylated brasilicardin carbohydrate side chain. Carbohydrate Research 504, p. 108312. Fulltext not available.

2020

Höring, Carina

, Seibel, Ulla

, Tropmann, Katharina, Grätz, Lukas

, Mönnich, Denise

, Pitzl, Sebastian, Bernhardt, Günther

, Pockes, Steffen

and Strasser, Andrea (2020) A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes. International Journal of Molecular Sciences 21 (22), p. 8440.

Antoni, Frauke

, Wifling, David

and Bernhardt, Günther

(2020) Water-soluble inhibitors of ABCG2 (BCRP) – A fragment-based and computational approach. European Journal of Medicinal Chemistry, p. 112958. Fulltext not available.

Forster, Lisa

, Grätz, Lukas, Mönnich, Denise, Bernhardt, Günther and Pockes, Steffen (2020) A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors. International Journal of Molecular Sciences 21 (17), p. 6103.

Biselli, Sabrina (2020) Synthesis and Pharmacological Characterization of Subtype-Selective Ligands, Including Radio- and Fluorescence Labeled Ligands, for the Histamine H₂ Receptor. PhD, Universität Regensburg.

Littmann, Timo (2020) Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment. PhD, Universität Regensburg.

Pegoli, Andrea (2020) Dibenzodiazepinone-type mAChR ligands: radio- and fluorescence labeling enable unveiling of dualsteric M₂R binding and conjugation to short peptides as an avenue to highly selective M₂R ligands. PhD, Universität Regensburg.

Bartole, Edith, Grätz, Lukas, Littmann, Timo, Wifling, David

, Seibel, Ulla, Buschauer, Armin

and Bernhardt, Günther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors. Journal of Medicinal Chemistry 63 (10), pp. 5297-5311. Fulltext not available.

Buschmann, Jonas, Seiler, Theresa, Bernhardt, Günther, Keller, Max and Wifling, David (2020) Argininamide-type neuropeptide Y Y1 receptor antagonists: the nature of Nω-carbamoyl substituents determines Y1R binding mode and affinity. RSC Medicinal Chemistry 11 (2), pp. 274-282. Fulltext not available.

Gruber, Corinna G., Pegoli, Andrea, Müller, Christoph, Grätz, Lukas, She, Xueke and Keller, Max (2020) Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry 11 (7), pp. 823-832. Fulltext not available.

Andreev, Stanislav, Pantsar, Tatu

, El-Gokha, Ahmed, Ansideri, Francesco, Kudolo, Mark, Anton, Débora Bublitz, Sita, Giulia

, Romasco, Jenny, Geibel, Christian, Lämmerhofer, Michael

, Goettert, Márcia Ines, Tarozzi, Andrea, Laufer, Stefan A. and Koch, Pierre (2020) Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability. International Journal of Molecular Sciences 21 (21), p. 7823. Fulltext not available.

Biselli, Sabrina, Alencastre, Inês, Tropmann, Katharina, Erdmann, Daniela, Chen, Mengya, Littmann, Timo, Maia, André F.

, Gomez-Lazaro, Maria, Tanaka, Miho, Ozawa, Takeaki, Keller, Max, Lamghari, Meriem, Buschauer, Armin and Bernhardt, Günther (2020) Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS Medicinal Chemistry Letters 11 (8), pp. 1521-1528. Fulltext not available.

Konieczny, Adam, Braun, Diana, Wifling, David

, Bernhardt, Günther and Keller, Max (2020) Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist. Journal of Medicinal Chemistry 63 (15), pp. 8198-8215. Fulltext not available.

She, Xueke, Pegoli, Andrea, Gruber, Corinna G., Wifling, David

, Carpenter, Jessica, Hübner, Harald, Chen, Mengya, Wan, Jianfei, Bernhardt, Günther, Gmeiner, Peter

, Holliday, Nicholas D.

and Keller, Max (2020) Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor. Journal of Medicinal Chemistry 63 (8), pp. 4133-4154. Fulltext not available.

Antoni, Frauke, Bause, Manuel, Scholler, Matthias, Bauer, Stefanie, Stark, Simone Alexandra, Jackson, Scott M., Manolaridis, Ioannis, Locher, Kaspar P., König, Burkhard

, Buschauer, Armin and Bernhardt, Günther (2020) Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). European Journal of Medicinal Chemistry 191. Fulltext not available.

2019

Maschauer, Simone, Ott, Julian J.

, Bernhardt, Günther, Kuwert, Torsten, Keller, Max and Prante, Olaf (2019) 18F-labelled triazolyl-linked argininamides targeting the neuropeptide Y Y1R for PET Imaging of mammary carcinoma. Scientific Reports 9, p. 12990.

Pegoli, Andrea, Wifling, David

, Gruber, Corinna G., Xueke, She, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter

and Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type
Muscarinic Acetylcholine Receptor Ligands Determines M2R
Selectivity. Journal of Medicinal Chemistry 62, pp. 5358-5369. Fulltext not available.

Schindler, Lisa, Bernhardt, Günther

and Keller, Max

(2019) Modifications at Arg and Ile Give Neurotensin(8−13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS Medicinal Chemistry Letters 10 (6), pp. 960-965. Fulltext not available.

Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard

, Tränkle, Christian and Decker, Michael (2019) Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism. ChemMedChem 14 (14), pp. 1349-1358. Fulltext not available.

Łażewska, Dorota

, Mogilski, Szczepan, Hagenow, Stefanie

, Kuder, Kamil, Głuch-Lutwin, Monika

, Siwek, Agata

, Więcek, Małgorzata, Kaleta, Maria, Seibel, Ulla, Buschauer, Armin, Filipek, Barbara, Stark, Holger

and Kieć-Kononowicz, Katarzyna (2019) Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands. Bioorganic & Medicinal Chemistry 27 (7), pp. 1254-1262. Fulltext not available.

Wifling, David

, Pfleger, Christopher, Kaindl, Jonas, Ibrahim, Passainte, Kling, Ralf C., Buschauer, Armin, Gohlke, Holger and Clark, Timothy (2019) Basal Histamine H4Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif. Chemistry – A European Journal 25 (64), pp. 14613-14624. Fulltext not available.

Andreev, Stanislav, Pantsar, Tatu, Ansideri, Francesco, Kudolo, Mark, Forster, Michael, Schollmeyer, Dieter, Laufer, Stefan A.

and Koch, Pierre (2019) Design, Synthesis and Biological Evaluation of 7-Chloro-9H-pyrimido[4,5-b]indole-based Glycogen Synthase Kinase-3β Inhibitors. Molecules 24 (12), p. 2331. Fulltext not available.

Agnetta, Luca, Bermudez, Marcel

, Riefolo, Fabio

, Matera, Carlo

, Claro, Enrique

, Messerer, Regina, Littmann, Timo, Wolber, Gerhard

, Holzgrabe, Ulrike and Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. Journal of Medicinal Chemistry 62 (6), pp. 3009-3020. Fulltext not available.

Scharrenbroich, Jessica, Kaever, Volkhard, Dove, Stefan, Seifert, Roland and Schneider, Erich H. (2019) Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode. Naunyn-Schmiedeberg's Archives of Pharmacology 392 (2), pp. 199-208. Fulltext not available.

Stolwijk, J. A., Skiba, M., Kade, C., Bernhardt, G., Buschauer, Armin

, Hübner, H., Gmeiner, P. and Wegener, Joachim

(2019) Increasing the throughput of label-free cell assays to study the activation of G-protein-coupled receptors by using a serial agonist exposure protocol. Integrative Biology 11 (3), pp. 99-108. Fulltext not available.

Gergs, U.

, Bernhardt, Günther, Buchwalow, I. B., Edler, H., Fröba, J., Keller, Max, Kirchhefer, U., Köhler, F., Mißlinger, N., Wache, H. and Neumann, J. (2019) Initial Characterization of Transgenic Mice Overexpressing Human Histamine H2 Receptors. Journal of Pharmacology and Experimental Therapeutics 369 (1), pp. 129-141. Fulltext not available.

Lachmann, Daniel, Konieczny, Adam, Keller, Max and König, Burkhard

(2019) Photochromic peptidic NPY Y4-receptor ligands. Organic & Biomolecular Chemistry 17, pp. 2467-2478. Fulltext not available.

Heider, Fabian

, Pantsar, Tatu, Kudolo, Mark, Ansideri, Francesco, De Simone, Angela, Pruccoli, Letizia, Schneider, Taiane, Goettert, Marcia Inês, Tarozzi, Andrea, Andrisano, Vincenza, Laufer, Stefan A. and Koch, Pierre (2019) Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks. ACS Medicinal Chemistry Letters 10 (10), pp. 1407-1414. Fulltext not available.

Heider, Fabian

, Ansideri, Francesco, Tesch, Roberta, Pantsar, Tatu, Haun, Urs, Döring, Eva, Kudolo, Mark, Poso, Antti

, Albrecht, Wolfgang, Laufer, Stefan A.

and Koch, Pierre (2019) Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors. European Journal of Medicinal Chemistry 175, pp. 309-329. Fulltext not available.

Littmann, Timo, Buschauer, Armin and Bernhardt, Günther (2019) Split luciferase-based assay for simultaneous analyses of the ligand concentration- and time-dependent recruitment of β-arrestin2. Analytical Biochemistry 573, pp. 8-16. Fulltext not available.

Ibrahim, Passainte, Wifling, David

and Clark, Timothy

(2019) Universal Activation Index for Class A GPCRs. Journal of Chemical Information and Modeling 59 (9), pp. 3938-3945. Fulltext not available.

Bartole, Edith, Littmann, Timo, Tanaka, Miho, Ozawa, Takeaki, Buschauer, Armin

and Bernhardt, Günther (2019) [3H]UR-DEBa176: A 2,4-Diaminopyrimidine-Type Radioligand Enabling Binding Studies at the Human, Mouse, and Rat Histamine H4 Receptors. Journal of Medicinal Chemistry 62 (17), pp. 8338-8356. Fulltext not available.

2018

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin and Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (17179), pp. 1-10.

Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brain J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David

, Bernhardt, Günther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C.

, Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin and Wu, Beili (2018) Structural basis of ligand binding modes at the
neuropeptide Y Y1 receptor. Nature 556, pp. 520-524. Fulltext not available.

Dukorn, Stefanie (2018) Pharmacological tools for the NPY receptors: [³⁵S]GTPγS binding assays, luciferase gene reporter assays and labeled peptides. PhD, Universität Regensburg.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin

and Bernhardt, Günther

(2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (1), p. 17179.

Brox, Regine, Milanos, Lampros, Saleh, Noureldin

, Baumeister, Paul, Buschauer, Armin, Hofmann, Dagmar, Heinrich, Markus R., Clark, Timothy and Tschammer, Nuska (2018) Molecular Mechanisms of Biased and Probe-Dependent Signaling at CXC-Motif Chemokine Receptor CXCR3 Induced by Negative Allosteric Modulators. Molecular Pharmacology 93 (4), pp. 309-322. Fulltext not available.

Jackson, Scott M., Manolaridis, Ioannis, Kowal, Julia

, Zechner, Melanie, Taylor, Nicholas M. I.

, Bause, Manuel, Bauer, Stefanie, Bartholomaeus, Ruben, Bernhardt, Günther, König, Burkhard

, Buschauer, Armin, Stahlberg, Henning

, Altmann, Karl-Heinz and Locher, Kaspar P. (2018) Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nature Structural & Molecular Biology 25 (4), pp. 333-340. Fulltext not available.

Dolles, Dominik, Hoffmann, Matthias, Gunesch, Sandra, Marinelli, Oliviero, Möller, Jan

, Santoni, Giorgio, Chatonnet, Arnaud, Lohse, Martin J.

, Wittmann, Hans-Joachim, Strasser, Andrea, Nabissi, Massimo, Maurice, Tangui and Decker, Michael

(2018) Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles. Journal of Medicinal Chemistry 61 (4), pp. 1646-1663. Fulltext not available.

2017

Kuhn, Kilian (2017) Molecular Tools for the NPY Y₄ Receptor Derived from the C-Terminus of hPP and from Argininamide-type Y₁R Antagonists. PhD, Universität Regensburg.

Strasser, Andrea, Wittmann, Hans-Joachim and Seifert, Roland (2017) Binding kinetics and pathways of ligands to GPCRs. Trends in Pharmacological Sciences. (In Press) Fulltext not available.

Xueke, She (2017) Synthesis and pharmacological characterization of dibenzodiazepinone-type heterodimeric and fluorescently labeled muscarinic receptor ligands. PhD, Universität Regensburg.

Dessauer, Carmen W., Watts, Val J., Ostrom, Rennolds S., Conti, Marco, Dove, Stefan and Seifert, Roland (2017) International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. Pharmacological Reviews 69 (2), pp. 93-139. Fulltext not available.

Wan, Jianfei (2017) Synthesis and pharmacological characterization of homo- and hetero-dimeric compounds, targeting the hH₁R and/or hH₄R. PhD, Universität Regensburg.

Dukorn, Stefanie, Littmann, Timo, Keller, Max, Kuhn, Kilian K., Cabrele, Chiara

, Baumeister, Paul, Bernhardt, Günther and Buschauer, Armin (2017) Fluorescence- and radio-labeling of Lys4,Nle17,30hPP yields molecular tools for the NPY Y4 receptor. Bioconjugate Chemistry. Fulltext not available.

Keller, Max

, Maschauer, Simone, Brennauer, Albert, Tripal, Philipp, Koglin, Norman, Dittrich, Ralf, Bernhardt, Günther, Kuwert, Torsten, Wester, Hans-Jürgen, Buschauer, Armin

and Prante, Olaf (2017) Prototypic 18F-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma. ACS Medicinal Chemistry Letters 8, pp. 304-309. Fulltext not available.

Wittmann, Hans-Joachim and Strasser, Andrea (2017) Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions? Naunyn-Schmiedeberg's Archives of Pharmacology. (In Press) Fulltext not available.

Kuhn, Kilian K., Littmann, Timo, Dukorn, Stefanie, Tanaka, Miho, Keller, Max, Ozawa, Takeaki, Bernhardt, Günther and Buschauer, Armin

(2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS Omega 2 (7), pp. 3616-3631.

2016

Strasser, Andrea and Wittmann, Hans-Joachim (2016) Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands. In: Handbook of Experimental Pharmacology. (In Press) Fulltext not available.

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. PhD, Universität Regensburg.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, pp. 610-625. (In Press) Fulltext not available.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver

and Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), pp. 6045-6058. Fulltext not available.

Plank, Nicole (2016) Dimeric histamine H2 receptor agonists as molecular tools and genetically engineered HEK293T cells as an assay platform to unravel signaling pathways of hH1R and hH2R. PhD, Universität Regensburg.

Geyer, Roland, Nordemann, Uwe, Strasser, Andrea, Wittmann, Hans-Joachim and Buschauer, Armin (2016) Conformational restriction and enantioseparation increase potency and selectivity of cyanoguanidine-type histamine H4 receptor agonists. Journal of Medicinal Chemistry 59 (7), pp. 3452-3470. Fulltext not available.

Huber, Stefan (2016) Investigations on bendamustine esters as new antitumor agents and the role of ABCG2 as a surrogate marker of breast cancer initiating cells. PhD, Universität Regensburg.

Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter and Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget 7 (12), pp. 14259-14278. Fulltext not available.

Felixberger, Johannes (2016) Luciferase complementation for the determination of arrestin recruitment: Investigations at histamine and NPY receptors. PhD, Universität Regensburg.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2016) Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter

, Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[ b , f ][1,4]oxazepines and dibenzo[ b , e ]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H 1 R, H 4 R, 5-HT 2A R and other selected GPCRs. Pharmacological Research 113, pp. 610-625. Fulltext not available.

Obreque-Balboa, José-Esteban, Sun, Qiu, Bernhardt, Günther, König, Burkhard

and Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. European Journal of Medicinal Chemistry 109, pp. 124-133. Fulltext not available.

Dove, Stefan (2016) Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites. In: Seifert, Roland, (ed.) Non-canonical Cyclic Nucleotides. Handbook of Experimental Pharmacology, 238. Springer International Publishing, Cham, Switzerland, pp. 49-66. ISBN 978-3-319-52673-7 (online), 978-3-319-52671-3 (print). Fulltext not available.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine

, Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara

, Vanderheyden, Patrick, Gmeiner, Peter

and Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), pp. 1925-1945. Fulltext not available.

2015

Werner, Kristin, Kälble, Solveig, Wolter, Sabine, Schneider, Erich H., Buschauer, Armin, Neumann, Detlef and Seifert, Roland (2015) Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor. Naunyn Schmiedebergs Archives of Pharmacology 388 (10), pp. 1039-1052. Fulltext not available.

Keller, Max, Schindler, Lisa, Bernhardt, Günther and Buschauer, Armin (2015) Towards labeled argininamide-type NPY Y1 receptor antagonists: Identification of a favorable propionylation site in BIBO3304. Archiv der Pharmazie 348 (6), pp. 390-398. Fulltext not available.

Rothenhöfer, Martin, Grundmann, Marco, Bernhardt, Günther, Matysik, Frank-Michael and Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC–PAD) for the sensitive determination of hyaluronan oligosaccharides. Journal of Chromatography B 988 (C), pp. 106-115. Fulltext not available.

Wifling, David (2015) Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs. PhD, Universität Regensburg.

Wifling, David, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), pp. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther and Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), pp. 83-93. Fulltext not available.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios

, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea and Decker, Michael (2015) Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders. ChemMedChem 11 (12), pp. 1270-1283. Fulltext not available.

Orlando, Zoya, Lengers, Isabelle, Melzig, Matthias F., Buschauer, Armin, Hensel, Andreas and Jose, Joachim (2015) Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors. Molecules 20 (9), pp. 15449-15468.

Wittmann, Hans-Joachim and Strasser, Andrea (2015) Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics. Bioorganic & Medicinal Chemistry Letters 25, pp. 1259-1268. Fulltext not available.

Lübker, Carolin, Dove, Stefan, Tang, Wei-Jen, Bieber Urbauer, Ramona J., Moskovitz, Jackob, Urbauer, Jeffrey L. and Seifert, Roland (2015) Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins 7 (7), pp. 2598-2614.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), pp. 3957-3969. Fulltext not available.

Huber, Stefan, Huettner, Johannes Philip, Hacker, Kristina, Bernhardt, Günther, König, Jörg and Buschauer, Armin (2015) Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells. PLoS One 10 (7), PLoSe0133743.

Beermann, Silke, Bernhardt, Guenther, Seifert, Roland, Buschauer, Armin and Neumann, Detlef (2015) Histamine H1- and H4-receptor signaling cooperatively regulate MAPK activation. Biochemical Pharmacology 98 (3), pp. 432-439. Fulltext not available.

Strasser, Andrea and Buschauer, Armin (2015) Histaminrezeptoren. Pharmakon 3 (2), pp. 109-116. Fulltext not available.

Radons, Jürgen, Falk, Werner and Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, pp. 15-20. Fulltext not available.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea, Bernhardt, Günther, Buschauer, Armin and Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), pp. 3970-3990. Fulltext not available.

Lübker, Carolin, Bieber-Urbauer, Ramona J., Moskovitz, Jackob, Dove, Stefan, Weisemann, Jasmin, Fedorova, Maria, Urbauer, Jeffrey L. and Seifert, Roland (2015) Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Biochemical Pharmacology 93 (2), pp. 196-209. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Schneider, Erich H. and Seifert, Roland (2015) Modulation of GPCRs by monovalent cations and anions. Naunyn-Schmiedeberg's Archives of Pharmacology 388, pp. 363-380. Fulltext not available.

Wifling, David, Löffel, Karolin, Nordemann, Uwe, Strasser, Andrea, Bernhardt, Günther, Dove, Stefan, Seifert, Roland and Buschauer, Armin (2015) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology 172, pp. 785-798. Fulltext not available.

Kaczor, Agnieszka, Guixa-Gonzalez, Ramon, Carrio, Pau, Poso, Antti, Dove, Stefan, Pastor, Manuel and Selent, Jana (2015) Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors. Molecular Informatics 34 (4), pp. 246-255. Fulltext not available.

Keller, Max, Weiss, Stefan, Hutzler, Christoph, Kuhn, Kilian K., Mollereau, Catherine, Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), pp. 8834-8849. Fulltext not available.

Huber, Stefan, Antoni, Frauke, Schickaneder, Christian, Schickaneder, Helmut, Bernhardt, Günther and Buschauer, Armin (2015) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC. Journal of Pharmaceutical and Biomedical Analysis 104, pp. 137-143. Fulltext not available.

Reinartz, Michael T., Kälble, Solveig, Littmann, Timo, Ozawa, Takeaki, Dove, Stefan, Kaever, Volkhard, Wainer, Irving W. and Seifert, Roland (2015) Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn-Schmiedeberg's archives of pharmacology 388 (1), pp. 51-65. Fulltext not available.

Untergehrer, Monika, Bücherl, Daniel, Wittmann, Hans-Joachim, Strasser, Andrea, Heilmann, Jörg and Jürgenliemk, Guido (2015) Structure-dependent deconjugation of flavonoid glucuronides by human beta-glucuronidase - in vitro and in silico analyses. Planta Med. 81 (12/13), pp. 1182-1189. Fulltext not available.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin and Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), pp. 707-716. Fulltext not available.

2014

Cuboni, Serena, Devigny, Christian, Hoogeland, Bastiaan, Strasser, Andrea, Pomplun, Sebastian, Hauger, Barbara, Höfner, Georg, Wanner, Klaus, Eder, Matthias, Buschauer, Armin, Holsboer, Florian and Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry 57 (22), pp. 9473-9479. Fulltext not available.

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors. PhD, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Thiele, Karinna Marie (2014) Charakterisierung Gαi3-gendefizienter Mauslinien. PhD, Universität Regensburg.

Meyer, Carolin (2014) Synthesis and structure-activity relationships of inhibitors of bacterial hyaluronidase: An approach to obtain compounds with drug-like properties. PhD, Universität Regensburg.

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), pp. 3-17.

Dove, Stefan, Danker, Kerstin Yvonne, Stasch, Johannes-Peter, Kaever, Volkhard and Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), pp. 598-607. Fulltext not available.

Bauer, Stefanie (2014) Quinoline carboxamides as modulators of Breast Cancer Resistance Protein (ABCG2): Investigations on potency, selectivity, mechanism of action, cytotoxicity, stability and drug-like properties. PhD, Universität Regensburg.

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. PhD, Universität Regensburg.

Pollinger, Klaus, Hennig, Robert, Bauer, Stefanie, Breunig, Miriam, Tessmar, Joerg, Buschauer, Armin, Witzgall, Ralph and Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319. Fulltext not available.

Wolter, Sabine, Dove, Stefan, Golombek, Marina, Schwede, Frank and Seifert, Roland (2014) N4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo. Naunyn-Schmiedeberg's archives of pharmacology 387 (12), pp. 1163-1175. Fulltext not available.

Werner, Kristin, Neumann, Detlef, Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), pp. 519-526. Fulltext not available.

Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2014) Sodium binding to hH3R and hH4R - a molecular modelling study. Journal of Molecular Modeling 20, p. 2394. Fulltext not available.

Geyer, Roland, Kaske, Melanie, Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88. Fulltext not available.

Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81. Fulltext not available.

2013

Schickaneder, Helmut, Buschauer, Armin, Bernhardt, Günther, Schickaneder, Christian, Limmert, Michael, Huber, Stefan, Lubbe, Mathias and Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof. Fulltext not available.

Sadek, Bassem, Alisch, Rudi, Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9. Fulltext not available.

Schreeb, Annemarie, Łażewska, Dorota, Dove, Stefan, Buschauer, Armin, Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564. Fulltext not available.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322. Fulltext not available.

Berlicki, Lukasz, Kaske, Melanie, Gutierrez-Abad, Raquel, Bernhardt, Günther, Illa, Ona, Ortuño, Rosa, Cabrele, Chiara, Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431. Fulltext not available.

Textor, Christian (2013) Small molecules as inhibitors of streptococcal hyaluronidase: a computer-assisted and multicomponent synthesis approach. PhD, Universität Regensburg.

Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie, Ochoa Puentes, Cristian, Sun, Qiu, Bause, Manuel, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), pp. 1773-1778. Fulltext not available.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. PhD, Universität Regensburg.

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. PhD, Universität Regensburg.

Brunskole Hummel, Irena, Kälble, Solveig, Burhenne, Heike, Reinartz, Michael T., Schwede, Frank, Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Hamberger, Janina (2013) Characterization of mammalian hyaluronidase-2 activity and identification of inhibitors of Streptococcal hyaluronan lyase. PhD, Universität Regensburg.

Ochoa-Puentes, Cristian, Bauer, Stefanie, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), pp. 393-396. Fulltext not available.

Pluym, Nikola, Baumeister, Paul, Keller, Max, Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593. Fulltext not available.

Seifert, Roland, Strasser, Andrea, Schneider, Erich H., Neumann, Detlef, Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Buschauer, Armin, Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32. Fulltext not available.

Seifert, Roland and Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), pp. 200-212. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, pp. 4443-4457. Fulltext not available.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. PhD, Universität Regensburg.

Bodensteiner, Julian, Baumeister, Paul, Geyer, Roland, Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-4055.

2012

Ertel, Miriam, Bernhardt, Günther, Nink, Jörg and Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems. Fulltext not available.

Memminger, Martin, Keller, Max, Lopuch, Miroslaw, Pop, Nathalie, Bernhardt, Günther, von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan, Hübner, Harald, Buschauer, Armin, Sanna, Fabrizio, Argiolas, Antonio, Melis, Maria Rosaria and Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154. Fulltext not available.

Rothenhöfer, Martin, Scherübl, Rosmarie, Bernhardt, Günther, Heilmann, Jörg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, pp. 169-77. Fulltext not available.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. PhD, Universität Regensburg.

Reher, Till M., Neumann, Detlef, Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203. Fulltext not available.

Seifert, Roland and Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak, Krzysztof and Lough, W. John and Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, pp. 274-293. ISBN 9781420092387. Fulltext not available.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160. Fulltext not available.

Göttle, Martin, Dove, Stefan and Seifert, Roland (2012) Bacillus anthracis edema factor substrate specificity: evidence for new modes of action. Toxins 4 (7), pp. 505-535.

Grundmann, Marco, Rothenhöfer, M., Bernhardt, Günther, Buschauer, Armin and Matysik, Frank-Michael (2012) Fast counter-electroosmotic capillary electrophoresis-time-of-flight mass spectrometry of hyaluronan oligosaccharides. Analytical and Bioanalytical Chemistry : Anal. Bioanal. Chem. 402, pp. 2617-2623. Fulltext not available.

Posavec, Damir, Zabel, Manfred, Bogner, Udo, Bernhardt, Günther and Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), pp. 7062-7069.

Taha, Hesham, Dove, Stefan, Geduhn, Jens, König, Burkhard, Shen, Yuequan, Tang, Wei-Jen and Seifert, Roland (2012) Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 monoand bis-(M)ANT-substituted nucleoside 5′-triphosphates. Naunyn-Schmiedeberg's Archives of Pharmacology (385), pp. 57-68. Fulltext not available.

Appl, Heidrun, Holzammer, Tobias, Dove, Stefan, Haen, Ekkehard, Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170. Fulltext not available.

Bernat, Viachaslau, Heinrich, Markus, Baumeister, Paul, Buschauer, Armin and Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), pp. 1481-1489. Fulltext not available.

Seifert, Roland and Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), pp. 343-351. Fulltext not available.

Keller, Max, Bhadbhade, Mohan M. and Read, Roger W. (2012) Two dibenzodiazepinone molecules with dissimilar dimeric associations and apparent different tautomeric forms. Acta Crystallogr. C 68 (6), o240-o246. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, pp. 3439-3444. Fulltext not available.

2011

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. PhD, Universität Regensburg.

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. PhD, Universität Regensburg.

Pluym, Nikola (2011) Application of the guanidine–acylguanidine bioisosteric approach to NPY Y2 receptor antagonists: bivalent, radiolabeled and fluorescent pharmacological tools. PhD, Universität Regensburg.

Birnkammer, Tobias (2011) Highly potent and selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships of mono- and bivalent ligands. PhD, Universität Regensburg.

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. PhD, Universität Regensburg.

Brunskole, Irena, Strasser, Andrea, Seifert, Roland and Buschauer, Armin (2011) Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation. Naunyn-Schmiedeberg's Archives of Pharmacology 384 (3), pp. 301-317. Fulltext not available.

Braun, Stephan, Botzki, Alexander, Salmen, Sunnhild, Textor, Christian, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. European Journal of Medicinal Chemistry 46 (9), pp. 4419-4429. Fulltext not available.

Pluym, Nikola, Brennauer, Albert, Keller, Max, Ziemek, Ralf, Pop, Nathalie, Bernhardt, Günther and Buschauer, Armin (2011) Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists. ChemMedChem 6 (9), pp. 1727-1738. Fulltext not available.

Posavec, Damir (2011) Adjustment of the decay kinetics of photogenerated endoperoxides embedded in various carrier materials aiming at medical applications. PhD, Universität Regensburg.

Geyer, Roland and Buschauer, Armin (2011) Synthesis and histamine H3 and H4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. Archiv der Pharmazie 344 (12), pp. 775-785. Fulltext not available.

Keller, Max, Bernhardt, Günther and Buschauer, Armin (2011) [3H]UR-MK136 - a highly potent and selective radioligand for neuropeptide Y Y1 receptors. ChemMedChem 6 (9), pp. 1566-1571. Fulltext not available.

Pop, Nathalie, Igel, Patrick, Brennauer, Albert, Cabrele, Chiara, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2011) Functional reconstitution of human neuropeptide Y (NPY) Y2 and Y4 receptors in Sf9 insect cells. Journal of Receptors and Signal Transduction 31 (4), pp. 271-285. Fulltext not available.

Keller, Max, Erdmann, Daniela, Teng, Shangjun, Pop, Nathalie, Pluym, Nikola, Bernhardt, Günther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878. Fulltext not available.

Schnell, David, Brunskole, Irena, Ladova, Katerina, Schneider, Erich H., Igel, Patrick, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2011) Expression and functional properties of canine, rat and murine histamine H4-receptors in Sf9 insect cells. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (5), pp. 457-470. Fulltext not available.

Seifert, Roland, Schneider, Erich H., Dove, Stefan, Brunskole, Irena, Neumann, Detlef, Strasser, Andrea and Buschauer, Armin (2011) Paradoxical stimulatory effects of the “standard” histamine H4-receptor antagonist JNJ7777120: The H4-receptor joins the club of 7TM receptors exhibiting functional selectivity. Molecular Pharmacology 79 (4), pp. 631-638. Fulltext not available.

Geduhn, Jens, Dove, Stefan, Shen, Yuequan, Tang, Wei-Jen, König, Burkhard and Seifert, Roland (2011) Bis-Halogen-Anthraniloyl-Substituted Nucleoside 5'-triphosphates as Potent and Selective Inhibitors of Bordetella pertussis CyaA. The Journal of pharmacology and experimental therapeutics 336 (1), pp. 104-115. Fulltext not available.

Silva, Maria Elena, Heim, Ralf, Strasser, Andrea, Elz, Sigurd and Dove, Stefan (2011) Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor. Journal of computer-aided molecular design 25 (1), pp. 51-66. Fulltext not available.

Erdmann, Daniela (2011) Histamine H2- and H3-receptor antagonists: Synthesis and characterization of radiolabelled and fluorescent pharmacological tools. PhD, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, pp. 1910-1918. Fulltext not available.

Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland and Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299. Fulltext not available.

Posavec, Damir, Dorsch, Andre, Bogner, Udo, Bernhardt, Guenther and Nagl, Stefan (2011) Polyvinyl butyral nanobeads: preparation, characterization, biocompatibility and cancer cell uptake. Microchimica acta 173 (3-4), pp. 391-399. Fulltext not available.

Ochoa Puentes, Cristian, Höcherl, Peter, Kühnle, Matthias, Bauer, Stefanie, Kürger, Kira, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). Bioorganic & Medicinal Chemistry Letters 21 (12), pp. 3654-3657. Fulltext not available.

Weiss, Stefan, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2011) Synthesis and characterization of DMAP-Modified NPY Y1 receptor antagonists as acyl-transfer catalysts. Collection of Czechoslovak chemical communications 76 (6), 763 -780. Fulltext not available.

2010

Igel, Patrick, Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199. Fulltext not available.

Pop, Nathalie (2010) Development of functional assays for human neuropeptide Y (Y1,2,4,5) receptors exploiting GTPase activity and (bio)luminescence as readout. PhD, Universität Regensburg.

Höcherl, Peter (2010) New tariquidar-like ABCB1 modulators in cancer chemotherapy:
Preclinical pharmacokinetic, pharmacodynamic investigations and computational studies. PhD, Universität Regensburg.

Hild, Wolfgang, Pollinger, Klaus, Caporale, Andrea, Cabrele, Chiara, Keller, Max, Pluym, Nicola, Buschauer, Armin

, Rachel, Reinhard

, Tessmar, Joerg, Breunig, Miriam and Goepferich, Achim

(2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672. Fulltext not available.

Ghorai, Prasanta, Kraus, Anja, Birnkammer, Tobias, Geyer, Roland, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176. Fulltext not available.

Kühnle, Matthias (2010) Experimental therapy and detection of glioblastoma: investigation of nanoparticles, ABCG2 modulators and optical imaging of intracerebral xenografts. PhD, Universität Regensburg.

Dayoub, Rania (2010) Expression and regulation of liver regeneration associated protein ALR under patho-physiological conditions. PhD, Universität Regensburg.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, pp. 333-341. Fulltext not available.

Kleinmaier, Roland, Igel, Patrick, Keller, Max, Buschauer, Armin and Gschwind, Ruth M. (2010) Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key. J. Am. Chem. Soc. 132 (32), pp. 11223-11233. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, pp. 1307-1318. Fulltext not available.

Schneider, Erich H., Schnell, David, Strasser, Andrea, Dove, Stefan and Seifert, Roland (2010) Impact of the DRY Motif and the Missing "Ionic Lock" on Constitutive Activity and G-Protein Coupling of the Human Histamine H-4 Receptor. Journal of Pharmacology and Experimental Therapeutics 333 (2), pp. 382-392. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, pp. 759-769. Fulltext not available.

Weiss, Stefan, Keller, Max, Bernhardt, G., Buschauer, Armin and König, Burkhard (2010) N(G)-Acyl-argininamides as NPY Y (1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. Bioorganic & Medicinal Chemistry (18), pp. 6292-6304. Fulltext not available.

2009

Mosandl, Johannes (2009) Radiochemical and luminescence-based binding and functional assays for human histamine receptors using genetically engineered cells. PhD, Universität Regensburg.

Igel, Patrick, Geyer, Roland, Straßer, Andrea, Dove, Stefan, Seifert, Roland and Buschauer, Armin (2009) Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists. Journal of Medicinal Chemistry 52 (20), pp. 6297-6313. Fulltext not available.

Keller, Max, Teng, Shangjun, Bernhardt, Günther and Buschauer, Armin (2009) Bivalent argininamide-type neuropeptide Y Y1 antagonists do not support the hypothesis of receptor dimerisation. ChemMedChem 4 (10), pp. 1733-1745. Fulltext not available.

Memminger, Martin (2009) Synthesis and characterization of subtype-selective estrogen receptor ligands and their application as pharmacological tools - Cross-talk between estrogen and NPY Y1 receptors in human breast cancer cells. PhD, Universität Regensburg.

Igel, Patrick, Schneider, Erich, Schnell, David, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2009) N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. Journal of Medicinal Chemistry 52 (8), pp. 2623-2627. Fulltext not available.

Kraus, Anja, Ghorai, Prasanta, Birnkammer, Tobias, Schnell, David, Elz, Sigurd, Seifert, Roland, Dove, Stefan, Bernhardt, Günther and Buschauer, Armin (2009) N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists. ChemMedChem 4 (2), pp. 232-240. Fulltext not available.

Igel, Patrick, Schnell, David, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2009) Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand. ChemMedChem 4 (2), pp. 225-231. Fulltext not available.

Kühnle, Matthias, Egger, Michael, Müller, Christine, Mahringer, Anne, Bernhardt, Günther, Fricker, Gert, König, Burkhard and Buschauer, Armin (2009) Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry 52 (4), pp. 1190-1197. Fulltext not available.

Keller, Max (2009) Guanidine-acylguanidine bioisosteric approach to address peptidergic receptors: pharmacological and diagnostic tools for the NPY Y1 receptor and versatile building blocks based on arginine substitutes. PhD, Universität Regensburg.

Igel, Patrick (2009) Synthesis and structure-activity relationships of NG-acylated arylalkylguanidines and related compounds as histamine receptor ligands: searching for selective H4R agonists. PhD, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, pp. 25-37. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Ciossek, Thomas, Baer, Thomas, Maier, Thomas and Beckers, Thomas (2009) Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases. Journal of medicinal chemistry 52 (8), pp. 2265-79. Fulltext not available.

Seifert, Roland and Dove, Stefan (2009) Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities. Mol. Pharmacol. 75 (1), pp. 13-18. Fulltext not available.

Taha, H. M., Schmidt, J., Göttle, M., Suryanarayana, S., Shen, Y., Tang, W.-J., Gille, A., Geduhn, Jens, König, Burkhard, Dove, Stefan and Seifert, Roland (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. Mol. Pharmacol. 75 (3), pp. 693-703. Fulltext not available.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), pp. 1061-1075. Fulltext not available.

2008

Keller, Max, Pop, Nathalie, Hutzler, Christoph, Beck-Sickinger, Annette G., Bernhardt, Günther and Buschauer, Armin (2008) Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. Journal of Medicinal Chemistry 51 (24), pp. 8168-8172. Fulltext not available.

Ghorai, Prasanta, Kraus, Anja, Keller, Max, Götte, Carsten, Igel, Patrick, Schneider, Erich, Schnell, David, Bernhardt, Günther, Dove, Stefan, Zabel, Manfred, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2008) Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists. Journal of Medicinal Chemistry 51 (22), pp. 7193-7204. Fulltext not available.

Weiss, Stefan, Keller, Max, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y(1) receptor antagonists. Bioorganic & Medicinal Chemistry 16 (22), pp. 9858-9866. Fulltext not available.

Kraus, Anja (2008) Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships. PhD, Universität Regensburg.

Spickenreither, Martin (2008) Inhibitors of bacterial and mammalian hyaluronidases: design, synthesis and structure-activity relationships with focus on human enzymes. PhD, Universität Regensburg.

Vogel, Susanne, Kaufmann, Doris, Pojarová, Michaela, Müller, Christine, Pfaller, Tobias, Kühne, Sybille, Bednarski, Patrick J. and Angerer, Erwin von (2008) Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. Bioorganic & Medicinal Chemistry 16 (12), pp. 6436-6447. Fulltext not available.

Kutta, Roger J., Hofinger, Edith S. A., Preuss, Hendrik, Bernhardt, Günther and Dick, Bernhard (2008) Blue-light induced interaction of LOV domains from Chlamydomonas reinhardtii. Chembiochem : a European journal of chemical biology 9 (12), pp. 1931-1938. Fulltext not available.

Hubensack, Martina, Müller, Christine, Höcherl, Höcherl, Fellner, Stephan, Spruss, Thilo, Bernhardt, Günther and Buschauer, Armin (2008) Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. Journal of Cancer Research and Clinical Oncology 134 (5), pp. 597-607. Fulltext restricted.

Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2008) Frontiers in medicinal chemistry in Regensburg. ChemMedChem 3 (8), pp. 1181-1184. Fulltext not available.

Hofinger, Edith S. A., Hoechstetter, Julia, Oettl, Martin, Bernhardt, Günther and Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. Glycoconjugate Journal 25 (2), pp. 101-109. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim and Seifert, Roland (2008) Ligand-specific contribution of the N-terminus and E2-loop to pharmacological properties of the histamine H1-receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 326 (3), pp. 783-791. Fulltext not available.

Dai, Jisen, Jian, Jinlong, Bosland, Maarten, Frenkel, Krystyna, Bernhardt, Günther and Huang, Xi (2008) Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status. Breast (Edinburgh, Scotland) 17 (2), pp. 172-179. Fulltext not available.

Bernhardt, Günther, Biersack, Bernhard, Bollwein, Susanne, Schobert, Rainer and Zoldakova, Miroslava (2008) Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells. Chemistry & biodiversity 5 (8), pp. 1645-1659. Fulltext not available.

2007

Kiewitz, Sebastian Donatus (2007) Structural investigations of the Id helix-loop-helix dimerization domain. PhD, Universität Regensburg.

Göttle, Martin, Dove, Stefan, Steindel, Phillip, Shen, Yuequan, Tang, Wei-Jen, Geduhn, Jens, König, Burkhard and Seifert, Roland (2007) Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides. Molecular Pharmacology 72 (3), pp. 526-535.

Preuß, Hendrik (2007) Species-selective interactions of histamine H2 receptors with guanidine-type agonists: molecular modelling, site-directed mutagenesis and pharmacological analysis. PhD, Universität Regensburg.

Müller, Christine (2007) New approaches to the therapy of glioblastoma: investigations on RNA interference, kinesin Eg5 and ABCB1/ABCG2 inhibition. PhD, Universität Regensburg.

Colombo, Noemi (2007) Synthesis and conformational analysis of polypeptides related to the inhibitor of the DNA binding and cell differentiation Id2. PhD, Universität Regensburg.

Svobodová, Jaroslava (2007) Id3, inhibitor of DNA binding and cell differentiation: synthesis and conformational analysis of the full-length protein and its truncated analogues. PhD, Universität Regensburg.

Hofinger, Edith (2007) Recombinant expression, purification and characterization of human hyaluronidases. PhD, Universität Regensburg.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors. Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 983-995.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity. Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 975-982.

Strasser, Andrea and Wittmann, Hans-Joachim (2007) Analysis of the activation mechanism of the guinea-pig histamine H1-receptor. J Comput Aided Mol Des : Journal of computer aided molecular design 21, pp. 499-509. Fulltext not available.

Kaufmann, Doris, Pojarová, Michaela, Vogel, Susanne, Liebl, Renate, Gastpar, Robert, Gross, Dietmar, Nishino, Tsuyuki, Pfaller, Tobias and Angerer, Erwin von (2007) Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells. Bioorganic & medicinal chemistry 15 (15), pp. 5122-36. Fulltext not available.

Brennauer, Albert, Keller, Max, Freund, Matthias, Bernhardt, Günther and Buschauer, Armin (2007) Decomposition of 1-(w-aminoalkanoyl)guanidines under alkaline conditions. Tetrahedron Letters 48 (39), pp. 6996-6999. Fulltext not available.

Ziemek, Ralf, Schneider, Erich, Kraus, Anja, Cabrele, Chiara, Beck-Sickinger, Annette G., Bernhardt, Günther and Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. Journal of Receptors and Signal Transduction 27 (4), pp. 217-233. Fulltext not available.

Xie, Sheng-Xue, Schalkhausser, Fabian, Ye, Qi-Zhuang, Seifert, Roland and Buschauer, Armin (2007) Effects of Impromidine- and Arpromidine-Derived Guanidines on Recombinant Human and Guinea Pig Histamine H₁ and H₂ Receptors. Archiv der Pharmazie 340 (1), pp. 9-16.

Zimmermann, Jochen and Angerer, Erwin von (2007) Estrogenic and antiestrogenic activities of 2,4-diphenylfuran-based ligands of estrogen receptors α and β. The Journal of Steroid Biochemistry and Molecular Biology 104 (3-5), pp. 259-268. Fulltext not available.

Mahboobi, Siavosh, Uecker, A., Cénac, C., Sellmer, A., Eichhorn, E., Elz, Sigurd, Böhmer, F.-D. and Dove, Stefan (2007) Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones. Bioorganic & medicinal chemistry 15 (5), pp. 2187-2197. Fulltext not available.

Müller, Christine, Gross, Dietmar, Sarli, Vasiliki, Gartner, Michael, Giannis, Athanassios, Bernhardt, Günther and Buschauer, Armin (2007) Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology 59 (2), pp. 157-164. Fulltext not available.

Hofinger, Edith S. A., Bernhardt, Günther and Buschauer, Armin (2007) Kinetics of Hyal1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction. Glycobiology 17 (9), pp. 963-971. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2007) LigPath: A module for predictive calculation of a ligands pathway into a receptor - application to the gpH1-receptor. J Mol Model : Journal of molecular modeling 13, pp. 209-218. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Spruss, Thilo, Maucher, Anton, Angerer, Erwin von, Schiller, Claus D., Schneider, Martin R., Gust, Ronald and Schönenberger, Helmut (2007) Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies. Journal of Cancer Research and Clinical Oncology 133 (3), pp. 153-167. Fulltext not available.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264. Fulltext restricted.

Hofinger, Edith S. A., Spickenreither, Martin, Oschmann, Jan, Bernhardt, Günther, Rudolph, Rainer and Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors. Glycobiology 17 (4), pp. 444-453. Fulltext not available.

Schobert, Rainer, Bernhardt, Günther, Biersack, Bernhard, Bollwein, Susanne, Fallahi, Magid, Grotemeier, Antje and Hammond, Geoffrey L. (2007) Steroid conjugates of dichloro(6-aminomethylnicotinate)platinum(II): effects on DNA, sex hormone binding globulin, the estrogen receptor, and various breast cancer cell lines. ChemMedChem 2 (3), pp. 333-342. Fulltext not available.

Schneider, Erich, Keller, Max, Brennauer, Albert, Hoefelschweiger, Bianca K., Gross, Dietmar, Wolfbeis, Otto S., Bernhardt, Günther and Buschauer, Armin (2007) Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist. ChemBioChem 8 (16), pp. 1981-1988. Fulltext restricted.

Egger, Michael, Li, Xuqin, Müller, Christine, Bernhardt, Günther, Buschauer, Armin and König, Burkhard (2007) Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter. European Journal of Organic Chemistry 2007 (16), pp. 2643-2649. Fulltext not available.

Pojarová, Michaela, Kaufmann, Doris, Gastpar, Robert, Nishino, Tsuyuki, Reszka, Przemyslaw, Bednarski, Patrick J. and Angerer, Erwin von (2007) [(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. Bioorganic & medicinal chemistry 15 (23), pp. 7368-7379. Fulltext not available.

2006

Brennauer, Albert (2006) Acylguanidines as bioisosteric groups in argininamide-type neuropeptide Y Y1 and Y2 receptor antagonists: synthesis, stability and pharmacological activity. PhD, Universität Regensburg.

Schulz, Berta (2006) Untersuchungen zur Opsonin-Aktivität von CRP, SAP, A-beta42 und SAA und deren Rolle bei der Schaumzellbildung. PhD, Universität Regensburg.

Ghorai, Prasanta (2006) Arpromidine-related acylguanidines: synthesis and structure-activity relationships of a new class of guanidine-type histamine H2 receptor agonists with reduced basicity. PhD, Universität Regensburg.

Gross, Dietmar (2006) New approaches to the chemotherapy of glioblastoma: investigations on doxorubicin nanoparticles, inhibition of PDGF receptors and kinesin Eg5, with emphasis on confocal laser-scanning microscopy. PhD, Universität Regensburg.

Ziemek, Ralf (2006) Development of binding and functional assays for the neuropeptide Y Y 2 and Y 4 receptors. PhD, Universität Regensburg.

Grandl, Margot (2006) Influence of E-LDL and Ox-LDL on the metabolism of ApoE, cholesterol, sphingolipids and glycosphingolipids as well as on the raft-composition in human macrophages. PhD, Universität Regensburg.

Zimmermann, Jochen (2006) Furan- and pyran-based heterocycles as subtype-selective ligands of the estrogen receptor. Synthesis and biological characterisation. PhD, Universität Regensburg.

Xie, Sheng-Xue, Kraus, Anja, Ghorai, Prasanta, Ye, Qi-Zhuang, Elz, Sigurd, Buschauer, Armin and Seifert, Roland (2006) N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors. Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268. Fulltext restricted.

Wabnitz, Tobias C., Rizzo, Simona, Götte, Carsten, Buschauer, Armin, Benincori, Tiziana and Reiser, Oliver (2006) Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles. Tetrahedron Letters 47 (22), pp. 3733-3736. Fulltext not available.

Schifferer, Rainer (2006) Charakterisierung des zellulären Lipideffluxes von primären, humanen Fibroblasten und Monozyten/Makrophagen. PhD, Universität Regensburg.

Braun, Stephan (2006) New inhibitors of bacterial hyaluronidase - synthesis and structure-activity relationships. PhD, Universität Regensburg.

Xie, Sheng-Xue, Ghorai, Prasanta, Ye, Qi-Zhuang, Buschauer, Armin and Seifert, Roland (2006) Probing Ligand-Specific Histamine H1- and H2-Receptor
Conformations with NG-Acylated Imidazolylpropylguanidines. The Journal of Pharmacology and Experimental Therapeutics 317 (1), pp. 139-146. Fulltext restricted.

Schneider, Erich, Mayer, Matthias, Ziemek, Ralf, Li, Liantao, Hutzler, Christoph, Bernhardt, Günther and Buschauer, Armin (2006) A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes. ChemBioChem 7 (9), pp. 1400-1409. Fulltext not available.

Rigden, Daniel J., Botzki, Alexander, Nukui, Masatoshi, Mewbourne, R. Brandon, Lamani, Ejvis, Braun, Stephan, von Angerer, Erwin, Bernhardt, Günther, Dove, Stefan, Buschauer, Armin and Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology 16 (8), pp. 757-765. Fulltext not available.

Ziemek, Ralf, Brennauer, Albert, Schneider, Erich, Cabrele, Chiara, Beck-Sickinger, Annette G., Bernhardt, Günther and Buschauer, Armin (2006) Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands. European Journal of Pharmacology 551 (1-3), pp. 10-8. Fulltext not available.

Spickenreither, Martin, Braun, Stephan, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. Bioorganic & Medicinal Chemistry Letters 16 (20), pp. 5313-5316. Fulltext not available.

Mahboobi, Siavosh, Uecker, A., Sellmer, A., Cénac, C., Höcher, H., Pongratz, H., Hufsky, H., Trümpler, A., Sicker, M., Heidel, F., Fischer, T., Stocking, C., Elz, Sigurd, Böhmer, F.-D. and Dove, Stefan (2006) Novel bis-(1H-indol-2-yl)-methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase. Journal of Medicinal Chemistry 49 (11), pp. 3101-3115. Fulltext not available.

Gross, Dietmar, Bernhardt, Günther and Buschauer, Armin (2006) Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: selective tyrosine kinase inhibitors lack antiproliferative activity. Journal of Cancer Research and Clinical Oncology 132 (9), pp. 589-599. Fulltext not available.

Xie, Sheng-Xue, Petrache, Georgiana, Schneider, Erich, Ye, Qi-Zhuang, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine. Bioorganic & Medicinal Chemistry Letters 16 (15), pp. 3886-3890. Fulltext not available.

2005

Maa Bared, Salim (2005) Identification and characterization of ABCA1-interactive proteins and their relevance to atherosclerosis. PhD, Universität Regensburg.

Hoechstetter, Julia (2005) Characterisation of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae. Investigations on the effect of pH on hyaluronan degradation and preclinical studies on the adjuvant administration of the enzymes in cancer chemotherapy. PhD, Universität Regensburg.

Pollak, Nils (2005) Die Rolle von MIF (macrophage migration inhibitory factor) in der Sepsis-induzierten Immunparalyse. PhD, Universität Regensburg.

Hubensack, Martina (2005) Approaches to overcome the blood-brain barrier in the chemotherapy of primary and secondary brain tumors: Modulation of P-glycoprotein 170 and targeting of the transferrin receptor. PhD, Universität Regensburg.

Hantschel, Markus (2005) Durchflusszytometrische Analysen zur Expression des Hitzeschockproteins Hsp70 auf der Zelloberfläche von kolorektalen Primärtumoren und hepatischen Metastasen, Magenkarzinomen, Bronchialkarzinomen, Kopf-Hals-Tumoren und akuten myeloischen Leukämien. PhD, Universität Regensburg.

Zimmermann, Jochen, Liebl, Renate and Angerer, Erwin von (2005) 2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha. The Journal of Steroid Biochemistry and Molecular Biology 94 (1-3), pp. 57-66. Fulltext not available.

Bouchal, Jan, Baumforth, Karl R. N., Sváchová, Michaela, Murray, Paul G., Angerer, Erwin von and Kolár, Zdenek (2005) Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines. The Journal of pharmacy and pharmacology 57 (1), pp. 83-92. Fulltext not available.

Botzki, Alexander, Salmen, Sunnhild, Bernhardt, Günther, Buschauer, Armin and Dove, Stefan (2005) Structure-Based Design Of Bacterial Hyaluronan Lyase Inhibitors,. QSAR & Combinatorial Science 24 (4), pp. 458-469. Fulltext not available.

Salmen, Sunnhild, Hoechstetter, Julia, Käsbauer, Christian, Paper, Dieter H., Bernhardt, Günther and Buschauer, Armin (2005) Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae. Planta Med. 71, pp. 727-732. Fulltext not available.

Gust, Ronald, Niebler, Karlheinz and Schönenberger, Helmut (2005) [N-Ethyl- and [N,N'-Diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II): Structure and Cytotoxic/Estrogenic Activity in Breast Cancer Cells. Journal of Medicinal Chemistry 48 (23), pp. 7132-7144. Fulltext not available.

2004

Wieser, Carsten (2004) Herpesvirus saimiri basierte Vektoren für die somatische Gentherapie der Rheumatoiden Arthritis. PhD, Universität Regensburg.

Botzki, Alexander (2004) Structure-based design of hyaluronidase inhibitors. PhD, Universität Regensburg.

Kießling, Stephan, Müller-Newen, Gerhard, Leeb, Sandra N., Hausmann, Martin, Rath, Heiko C., Strater, Jörn, Spottl, Tanja, Schlottmann, Klaus, Grossmann, Johannes, Montero-Julian, F. A., Schölmerich, Jürgen, Andus, Tilo, Buschauer, Armin, Heinrich, Peter C. and Rogler, Gerhard (2004) Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells. The Journal of Biological Chemistry 279 (11), pp. 10304-10315. Fulltext not available.

Salmen, Sunnhild (2004) Inhibitors of bacterial and mammalian hyaluronidase - Synthesis and structure-activity relationships. PhD, Universität Regensburg.

Walter, Georg, Liebl, Renate and Angerer, Erwin von (2004) 2-phenylindole sulfamates: inhibitors of steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology 88 (4-5), pp. 409-420. Fulltext not available.

Bernhardt, Günther, Brunner, Henri, Gruber, Nick, Lottner, Christian, Pushpan, Simi K., Tsuno, Takashi and Zabel, Manfred (2004) Carboplatin derivatives with superior antitumor activity compared to the parent compound. Inorganica Chimica Acta 357 (15), pp. 4452-4466. Fulltext not available.

Dittmar, Michael, Kiourkenidis, Georgios, Horn, Markus, Bollwein, Susanne and Bernhardt, Günther (2004) Cerebral ischemia, matrix metalloproteinases, and TNF-alpha: MMP inhibitors may act not exclusively by reducing MMP activity. Stroke 35 (7), e338-e340. Fulltext not available.

Lottner, Christian, Knuechel, Ruth, Bernhardt, Günther and Brunner, Henri (2004) Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(II) conjugates. Cancer letters 203 (2), pp. 171-180. Fulltext not available.

Gürtler, Ulrich, Fuchs, Peter, Stangelmayer, Achim, Bernhardt, Günther, Buschauer, Armin and Spruss, Thilo (2004) Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion. Archiv der Pharmazie 33 (12), pp. 672-681. Fulltext not available.

Lottner, Christian, Knuechel, Ruth, Bernhardt, Günther and Brunner, Henri (2004) Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells. Cancer letters 215 (2), pp. 167-177. Fulltext not available.

Botzki, Alexander, Rigden, Daniel J., Braun, Stephan, Nukui, Masatoshi, Salmen, Sunnhild, Hoechstetter, Julia, Bernhardt, Günther, Dove, Stefan, Buschauer, Armin and Jedrzejas, Mark J. (2004) L-ascorbic acid-6-hexadecanoate, a potent hyaluronidase inhibitor: X-ray structure and molecular modeling of enzyme-inhibitor complexes. The Journal of Biological Chemistry 279 (44), pp. 45990-45997. Fulltext not available.

Dove, Stefan (2004) Picolinic Acids as Inhibitors of Dopamine b-Monooxygenase: QSAR and Putative Binding Site. Archiv der Pharmazie 337 (12), pp. 645-653. Fulltext not available.

Walter, Georg, Liebl, Renate and Angerer, Erwin von (2004) Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells. Archiv der Pharmazie 337 (12), pp. 634-644. Fulltext not available.

Dove, Stefan, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H_2 Receptor Ligands,. Mini-Rev. Med. Chem. 4 (9), pp. 941-954. Fulltext not available.

Brennauer, Albert, Dove, Stefan and Buschauer, Armin (2004) 18. Structure-Activity Relationships of Nonpeptide Neuropeptide Y Receptor Antagonists. In: Michel, M. C., (ed.) Neuropeptide Y and Related Peptides. Handbook of Experimental Pharmacology, 162 (18). Springer, Heidelberg, pp. 505-546. ISBN 978-3-540-40581-8. Fulltext not available.

Walter, Georg, Liebl, Renate and Angerer, Erwin von (2004) Synthesis and biological evaluation of stilbene-based pure estrogen antagonists. Bioorganic & Medicinal Chemistry Letters 14 (18), pp. 4659-4663. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruß, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), pp. 335-348. Fulltext not available.

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruss, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. Archiv der Pharmazie 337 (6), pp. 349-359. Fulltext not available.

2003

Hähnel, Viola (2003) Die transkriptionelle Regulation der Toll-like Rezeptoren (TLR2, TLR3 und TLR4) in mononukleären Phagozyten. PhD, Universität Regensburg.

Graichen, Florian (2003) Neuropeptid Y Y1-Rezeptorantagonisten der Argininamid-Reihe: Entwicklung von Synthesemethoden an polymeren Trägern und Strategien zur Herstellung von Radioliganden. PhD, Universität Regensburg.

Stopfer, Peter (2003) Biologische Wirkungen der Aktivierung des Lymphotoxin-beta-Rezeptors. PhD, Universität Regensburg.

Heinz, Sven (2003) Identification and characterization of genes with specific expression in dendritic cells. PhD, Universität Regensburg.

Parker, Steven L., Parker, Michael S., Buschauer, Armin and Balasubramaniam, Ambikaipakan (2003) Ligand internalization by cloned neuropeptide Y Y5 receptors excludes Y2 and Y4 receptor-selective peptides. European Journal of Pharmacology 474 (1), pp. 31-42. Fulltext not available.

Li, Liantao, Mayer, Matthias, Schneider, Erich, Schreiber, Elvira, Bernhardt, Günther, Peng, Shiqi and Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. Arch Pharm (Weinheim) 336 (12), pp. 585-590. Fulltext not available.

Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther, Elz, Sigurd and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine,. Bioorganic & Medicinal Chemistry Letters 13 (10), 0960-894. Fulltext not available.

Böhmer, F. D., Karagyozov, L., Uecker, A., Serve, H., Botzki, A., Mahboobi, Siavosh and Dove, Stefan (2003) A single amino acid exchange inverts susceptibility of related receptor tyrosine kinases for the ATP-site inhibitor STI-571. The Journal of Biological Chemistry 278 (7), pp. 5148-5155. Fulltext not available.

Oettl, Martin, Hoechstetter, Julia, Asen, Iris, Bernhardt, Günther and Buschauer, Armin (2003) Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations. European Journal of Pharmaceutical Sciences 18 (3-4), pp. 267-277. Fulltext not available.

Seifert, Roland, Wenzel-Seifert, Katharina, Bürckstümmer, Tilmann, Pertz, Heinz H., Schunack, Walter, Dove, Stefan, Buschauer, Armin and Elz, Sigurd (2003) Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor,. Journal of Pharmacology and Experimental Therapeutics 305, pp. 1104-1115. Fulltext not available.

Bart, Karl-Christian, Bernhardt, Günther, Brunner, Henri and Lottner, Christian (2003) Preparation of novel, water-soluble porphyrin platinum amine compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases. Fulltext not available.

Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,. Bioorganic & Medicinal Chemistry Letters 13 (7), pp. 1245-1248. Fulltext not available.

Klein, Michael, Zabel, Manfred, Bernhardt, Günther and König, Burkhard (2003) Tetrahydroxy 10-membered cyclic enediynes. The Journal of organic chemistry 68 (24), pp. 9379-9383. Fulltext not available.

Radons, Jürgen, Dove, Stefan, Neumann, D., Altmann, R., Botzki, Alexander, Martin, M. U. and Falk, Werner (2003) The IL-1 receptor accessory protein TIR domain: analysis of putative interaction sites by in-vitro mutagenesis and molecular modeling. The Journal of Biological Chemistry 278 (49), pp. 49145-49153. Fulltext not available.

2002

Mayer, Matthias (2002) Entwicklung fluorimetrischer Methoden zur Bestimmung der Affinität und Aktivität von Liganden G-Protein-gekoppelter Rezeptoren an intakten Zellen. PhD, Universität Regensburg.

Kießling, Stephan (2002) Funktionelle Untersuchungen zur Expression des Interleukin-11 Rezeptors alpha in humanen Kolonepithelzellen. PhD, Universität Regensburg.

Parker, S. L., Parker, M. S., Lundell, I., Balasubramaniam, A., Buschauer, Armin, Kane, J. K., Yalcin, A. and Berglund, M. M. (2002) Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling. Regulatory Peptides 107 (1-3), pp. 49-62. Fulltext not available.

Mahboobi, Siavosh, Teller, S., Pongratz, H., Hufsky, H., Sellmer, A., Botzki, Alexander, Uecker, A., Beckers, T., Baasner, S., Schächtele, C., Überall, F., Kassack, M. U., Dove, Stefan and Böhmer, F.-D. (2002) Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. Journal of Medicinal Chemistry 45 (5), pp. 1002-1018. Fulltext not available.

Vogelhuber, Werner, Spruß, Thilo, Bernhardt, Günther, Buschauer, Armin and Göpferich, Achim (2002) Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,. International Journal of Pharmaceutics 238 (1-2), pp. 111-121. Fulltext not available.

Bernhardt, Günther, Beckenlehner, Karin, Spruss, Thilo, Schlemmer, Richard, Reile, Herta and Schönenberger, Helmut (2002) Establishment and Characterization of New Murine Breast Cancer Cell Lines. Archiv der Pharmazie 335 (2), pp. 55-68. Fulltext not available.

Bernhardt, Günther, Beckenlehner, Karin, Spruss, Thilo, Schlemmer, Richard, Reile, Herta and Schönenberger, Helmut (2002) Establishment and characterization of new murine breast cancer cell lines. Archiv der Pharmazie 335 (2-3), pp. 55-68. Fulltext not available.

Lottner, Christian, Bart, Karl-Christian, Bernhardt, Günther and Brunner, Henri (2002) Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity. Journal of medicinal chemistry 45 (10), pp. 2064-2078. Fulltext not available.

Weiss, Thomas S.

, Bernhardt, Günther, Buschauer, Armin, Thasler, Wolfgang E., Dolgner, Doris, Zirngibl, Hubert and Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,. International Journal of Colorectal Disease 17 (6), pp. 381-387. Fulltext not available.

Lottner, Christian, Bart, Karl-Christian, Bernhardt, Günther and Brunner, Henri (2002) Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents. Journal of medicinal chemistry 45 (10), pp. 2079-2089. Fulltext not available.

Golob, Thomas, Liebl, Renate and Angerer, Erwin von (2002) Sulfamoyloxy-substituted 2-phenylindoles: antiestrogen-based inhibitors of the steroid sulfatase in human breast cancer cells. Bioorganic & Medicinal Chemistry 10 (12), pp. 3941-3953. Fulltext not available.

Bouchal, Jan, Kolár, Zdenek, Mad'arová, Jana, Hlobilková, Alice and Angerer, Erwin von (2002) The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP. Biochemical Pharmacology 63 (6), pp. 1177-81. Fulltext not available.

Fellner, Stephan, Bauer, Björn, Miller, David S., Schaffrick, Martina, Fankhänel, Martina, Spruß, Thilo, Bernhardt, Günther, Graeff, Claudia, Färber, Lothar, Gschaidmeier, Harald, Buschauer, Armin and Fricker, Gert (2002) Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. The Journal of Clinical Investigation 110 (9), pp. 1309-1318.

2001

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther, Gust, Ronald and Schönenberger, Helmut (2001) 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties. Archiv der Pharmazie 334 (4), pp. 125-137. Fulltext not available.

Dove, Stefan (2001) Alignment of molecules by weighted field fit considering active shape. In: Höltje, H.-D. and Sippl, W., (eds.) Rational Approaches to Drug Design - 13th European Symposium on QSAR. J. R. Prous Science, S. A., Barcelona, Philadelphia, 316 - 322. Fulltext not available.

Dove, Stefan (2001) Arzneistoffe aus dem Computer – Modellierung molekularer Schlüssel für biologische Schlösser. Blick in die Wissenschaft (Forschungsmagazin Univ. Regensburg) 13, pp. 22-26. Fulltext not available.

Schuster, Andreas, Götte, Carsten, Bernhardt, Günther and Buschauer, Armin (2001) Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods,. Chirality 13 (6), pp. 285-293. Fulltext not available.

Kelley, Melissa T., Bürckstümmer, Tilmann, Wenzel-Seifert, Katharina, Dove, Stefan, Buschauer, Armin and Seifert, Roland (2001) Distinct interaction of human and guinea pig histamine H_2-Receptor with guanidine-type agonists,. Molecular Pharmacology 60 (6), pp. 1210-1225. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2001) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound. Archiv der Pharmazie 334 (10), pp. 309-317. Fulltext not available.

Bischoff, Andrea, Püttmann, Kristina, Kötting, Annette, Moser, Christiane, Buschauer, Armin and Michel, Martin C. (2001) Limited signal transduction repertoire of human Y_5 neuropeptide Y receptors expressed in HEC-B cells. Peptides 22 (3), pp. 387-394. Fulltext not available.

Vogelhuber, W., Rutunno, P., Magni, E., Gazzaniga, A., Spruss, Thilo, Bernhardt, Günther, Buschauer, Armin and Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), pp. 75-88. Fulltext not available.

Wenzel-Seifert, Katharina, Kelley, Melissa T., Buschauer, Armin and Seifert, Roland (2001) Similar apparent constitutive activity of human histamine H_2-receptor fused to long and short splice variants of Gsa,. Journal of Pharmacology and Experimental Therapeutics 299 (3), pp. 1013-1020. Fulltext not available.

Meiers, S., Kemény, M., Weyand, U., Gastpar, R., Angerer, E. von and Marko, D. (2001) The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. Journal of Agricultural and Food Chemistry 49 (2), pp. 958-962. Fulltext not available.

2000

Zabel, Manfred, Breu, Josef, Rau, Franz, Range, Klaus-Jürgen, Krey, Volker, Uffrecht, Anka and Buschauer, Armin (2000) Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists. Acta Crystallographica Section C 56, pp. 250-251. Fulltext not available.

Golob, T., Biberger, C., Walter, G. and Angerer, E. von (2000) Antiestrogenic activities of 3,8-dihydroxy-6,11-dihydrobenzo[a]carbazoles with sulfur-containing side chains. Archiv der Pharmazie 333 (9), pp. 305-311. Fulltext not available.

Moser, Christiane, Bernhardt, Günther, Michel, J., Schwarz, H. and Buschauer, Armin (2000) Cloning and functional expression of the hNPY Y_5 receptor in human endometrial cancer (HEC-1B) cells. Can J. Physiol. Pharmacol 78, pp. 134-142. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F1 mice. Archiv der Pharmazie 333 (12), pp. 404-414. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process. Archiv der Pharmazie 333 (2-3), pp. 69-71. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice. Archiv der Pharmazie 333 (12), pp. 397-403. Fulltext not available.

Buschauer, Armin, Bernhardt, Günther and Dove, Stefan (2000) NPY-Rezeptoren als Zielstrukturen für neue Arzneistoffe. Pharmazeutische Zeitung 24, pp. 11-18. Fulltext not available.

Dove, Stefan, Michel, Martin C., Knieps, Sebastian and Buschauer, Armin (2000) Pharmacology and quantitative structure-activity relationships of imidazolylpropylguanidines with mepyramine-like substructures as non-peptide neuropeptide Y Y_1 receptor antagonists,. Can. J. Physiol. Pharmacol 78, pp. 108-115. Fulltext not available.

Aiglstorfer, Iris, Hendrich, Ingo, Moser, Christiane, Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2000) Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,. Bioorganic & Medicinal Chemistry Letters 10 (14), pp. 1597-1600. Fulltext not available.

Gust, Ronald, Faderl, Michael and Schönenberger, Helmut (2000) [Aqua-1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine] sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring 3. Investigation of breast cancer inhibiting properties. Journal of cancer research and clinical oncology 126 (11), pp. 647-654. Fulltext not available.

1999

Meister, A., Bernhardt, Günther, Christoffel, V. and Buschauer, Armin (1999) Antispasmodic Activity of Thymus vulgaris, Extract on the Isolated Guinea-Pig Trachea: Discrimination Between Drug and Ethanol Effects. Planta Med 1999, pp. 512-516. Fulltext not available.

Moser, Christiane, Bernhardt, Günther and Buschauer, Armin (1999) Efficient Transfection of Human Endometrial Cancer (HEC-1B) Cells with FuGENE^TM 6 Transfection Reagent. biochemica 1/1999, pp. 26-27. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Kuhr, S. and Popp, A. (1999) Homo-arcyriaflavin: The synthesis of ring-expanded arcyriaflavin analogs. The Journal of Organic Chemistry 64 (22), pp. 8130-8137. Fulltext not available.

Dove, Stefan and Buschauer, Armin (1999) Improved Alignment by Weighted Field Fit in CoMFA of Histamine H_2 Receptor Agonistic Imidazolylpropylguanidines. Quant. Struct.-Act. Relat. 18 (4), pp. 329-341. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Kuhr, S. and Pongratz, Herwig (1999) Synthesis of arcyriarubine regioisomers by Pd(0)-catalysis or via lithiated indole derivatives - conformational analysis by semiempirical and X-ray methods. Pharmazie 54 (11), pp. 820-827. Fulltext not available.

Gust, Ronald, Heinrich, Heike, Krauser, Rudolf and Schönenberger, Helmut (1999) [Meso- and rac-1,2-bis(4-fluorophenyl)ethylenediamine]chloro[sulfinylbis(methane)-S]platinum(II) chloride new water soluble platinum complexes with high anti-breast cancer activities. Inorganica chimica acta 285 (2), pp. 184-189. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl) ethylenediamine]dichloroplatinum(II), a compound with a specific activity on hormone-sensitive breast cancers--evidence for a diethylstilbestrol-like mode of action. Archiv der Pharmazie 332 (2), pp. 59-69. Fulltext not available.

Bernhardt, Günther, Koch, Marion, Spruss, Thilo, Gust, Ronald, Krauser, Rudolf, Schlemmer, Richard, Hollstein, Michael, Lux, Franz and Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] sulfatoplatinum(II)--pharmacokinetic studies. Archiv der Pharmazie 332 (6), pp. 195-200. Fulltext not available.

1998

Biberger, C. and Angerer, E. von (1998) 1-Benzyl-2-phenylindole- and 1,2-diphenylindole-based antiestrogens. Estimation of agonist and antagonist activities in transfection assays. The Journal of Steroid Biochemistry and Molecular Biology 64 (5-6), pp. 277-285. Fulltext not available.

Leichtl, S. and Angerer, E. von (1998) 2-Phenylbenzo[b]thiophene-based antiestrogens with mammary tumor inhibiting activity. Archiv der Pharmazie 331 (9), pp. 283-289. Fulltext not available.

Schuster, Andreas, Bernhardt, Günther, Eibler, Ernst, Buschauer, Armin and Hesselink, Willy (1998) Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with HPLC and CZE. Journal of Chromatography A 793 (1), pp. 77-90. Fulltext not available.

Schulze, Frank R., Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part I. Pharmacological hybrids with pheniramine- and roxatidine-like substructures ,. European Journal of Pharmaceutical Sciences 6, pp. 177-186. Fulltext not available.

Wolf, Cornelia, Schulze, Frank R., Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part II. Pharmacological hybrids with pheniramine- and tiotidine-like substructures,. European Journal of Pharmaceutical Sciences 6 (3), pp. 187-196. Fulltext not available.

Dove, Stefan (1998) Computermethoden im Arzneimitteldesign. In: Lehner, L. and Braungart, G. and Hitzenberger, L., (eds.) Multimedia in Lehre und Forschung. Gabler Edition Wissenschaft. Gabler Verlag, Deutscher Universitäts-Verlag, Wiesbaden, 75 - 88. ISBN 3-8244-6602-3. Fulltext not available.

Mayer, Klaus K., Dove, Stefan, Pongratz, Herwig, Ertan, M. and Wiegrebe, Wolfgang (1998) Electron impact induced fragmentation of 4-aryl-4,6,7,8-tetrahydro-1H,3H-quinazolinone-2,5-diones. Heterocycles 48 (6), pp. 1169-1183. Fulltext not available.

Pillwein, Konrad, Fuiko, R., Slavc, I., Czech, T., Hawliczek, G., Bernhardt, Günther, Nirnberger, Gunther and Koller, U. (1998) Hyaluronidase additional to standard chemotherapy improves outcome for children with malignant brain tumors. Cancer Letters (Shannon, Ireland) 131 (1), pp. 101-108. Fulltext not available.

Dove, Stefan and Buschauer, Armin (1998) Imidazolylpropylguanidines as histamine H_2 receptor agonists: 3D-QSAR of a large series. Pharm. Acta Helv. 73 (3), pp. 145-155. Fulltext not available.

Gastpar, R., Goldbrunner, M., Marko, D. and Angerer, E. von (1998) Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. Journal of Medicinal Chemistry 41 (25), pp. 4965-4972. Fulltext not available.

Aiglstorfer, Iris, Uffrecht, Anka, Geßele, K., Moser, Christiane, Schuster, Andreas, Merz, S., Malawska, B., Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (1998) NPY Y_1 antagonists: structure-activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures. Regul. Pept. 75, pp. 75-76. Fulltext not available.

Muckenschnabel, I., Bernhardt, Günther, Spruß, Thilo and Buschauer, Armin (1998) Pharmacokinetics and tissue distribution of bovine testicular hyaluronidase and vinblastine in mice: an attempt to optimize the mode of adjuvant hyaluronidase administration in cancer chemotherapy. Cancer Letters 131 (1), pp. 71-84. Fulltext not available.

Muckenschnabel, Ingo, Bernhardt, Günther, Spruß, Thilo, Dietl, Barbara and Buschauer, Armin (1998) Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers. Cancer Letters 131, pp. 13-20. Fulltext not available.

Gust, Ronald, Schnurr, Beate, Krauser, Rudolf, Bernhardt, Günther, Koch, Marion, Schmid, Beate, Hummel, Evelyn and Schönenberger, Helmut (1998) Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. Journal of Cancer Research and Clinical Oncology 124 (11), pp. 585-597. Fulltext not available.

Schuster, Andreas, Bollwein, Susanne, Uffrecht, Anka, Krey, Volker, Götte, Carsten, Bernhardt, Günther and Buschauer, Armin (1998) Stereochemical Investigations on Intermediates for the Synthesis of Histamine H_2 Receptor Agonists and Neuropeptide Y Y_1 Antagonists: Chiral Separation of Phenyl(pyridyl)alkanoic Acids by HPLC and CE. Sci. Pharm 66, pp. 263-278. Fulltext not available.

Gust, Ronald, Krauser, Rudolf, Schmid, Beate and Schönenberger, Helmut (1998) Synthesis and antitumor activity of [1,2-bis(4-fluorophenyl)ethylenediamine][dicarboxylato]platinum(II) complexes. Archiv der Pharmazie 331 (1), pp. 27-35. Fulltext not available.

1997

Muckenschnabel, I., Bernhardt, Günther, Spruß, Thilo and Buschauer, Armin (1997) A versatile HPLC method for the measurement of melphalan tailored to the optimization of hyperthermic isolated limb perfusion,. Eur. J. Pharm. Sci. 5, pp. 129-137. Fulltext not available.

Märkl, Gottfried, Stiegler, J., Kreitmeier, Peter, Burgemeister, Thomas, Kastner, F. and Dove, Stefan (1997) Configurational and conformational isomeric antiaromatic [28]tetraoxaporphyrinoids(4.2.4.2) and aromatic [26]tetraoxaporphyrin(4.2.4.2) dications. A new type of molecular dynamics in macrocyclic systems. Helvetica Chimica Acta 80 (1), pp. 14-42. Fulltext not available.

Schuster, Andreas, Bernhardt, Günther and Buschauer, Armin (1997) Determination of the arpromidine-type histamine H2-receptor agonist N1-[3-(3,4-difluorophenyl)-3-(2-pyridyl)propyl]-N2-[3-(1H-imidazol-4-yl)propyl]guanidine and corresponding N3-alkoxycarbonylguanidines by HPLC and CE. Eur. J. Pharm. Sci. 5, pp. 79-88. Fulltext not available.

Weiss, Thomas S.

, Bernhardt, Günther, Buschauer, Armin, Jauch, Karl-Walter and Zirngibl, Hubert (1997) High-resolution RP HPLC analysis of polyamines and their monoacetyl conjugates by fluorescence detection after derivatization with N-hydroxy-succinimidyl 6-quinolinyl carbamate. Anal. Biochem 247, pp. 294-304. Fulltext not available.

Goldbrunner, M., Loidl, G., Polossek, T., Mannschreck, A. and Angerer, E. von (1997) Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives. Journal of Medicinal Chemistry 40 (22), pp. 3524-3533. Fulltext not available.

Buschauer, Armin (1997) Pharmakotherapie der Tuberkulose: Wirkmechanismen und Resistenzen,. Pharm. Ztg. 142, pp. 209-223. Fulltext not available.

Dove, Stefan and Buschauer, Armin (1997) Stepwise leave-one-isomer-out Free-Wilson approaches as preprocessing tools in QSAR analysis of racemates. Quant. Struct.-Act. Relat. 16, pp. 11-19. Fulltext not available.

Müller, Manfred, Knieps, Sebastian, Geßele, Karin, Dove, Stefan, Bernhardt, Günther and Buschauer, Armin (1997) Synthesis and neuropeptide Y Y1 receptor antagonistic activity of N,N-disubstituted w -guanidino- and w -aminoalkanoic acid amides. Arch. Pharm. - Pharm. Med. Chem. (Weinheim) 330, pp. 333-342. Fulltext not available.

Gust, Ronald, Gelbcke, Michael, Angermaier, Bernhard, Bachmann, Helmut, Krauser, Rudolf and Schönenberger, Helmut (1997) The stereoselectivity of antitumor active [1,2-diamino-1-phenylpropane]dichloroplatinum(II) complexes. Inorganica chimica acta 264 (1-2), pp. 145-160. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Bednarski, P. J., Kuhr, S., Burgemeister, Thomas and Schollmeyer, D. (1997) X-Ray Crystal Structure of Woodinine and Conformational Analysis by Means of Semiempirical and 1H-NMR Methods. Journal of Natural Products-Copublished with the Am. Soc. of Pharmacognosy 60 (6), pp. 587-591. Fulltext not available.

1996

Biberger, C. and Angerer, E. von (1996) 2-Phenylindoles with sulfur containing side chains. Estrogen receptor affinity, antiestrogenic potency, and antitumor activity. The Journal of Steroid Biochemistry and Molecular Biology 58 (1), pp. 31-43. Fulltext not available.

Gust, Ronald, Krauser, Rudolf, Schmid, Beate and Schönenberger, Helmut (1996) Breast cancer inhibiting diastereomeric diacetato[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) derivatives: synthesis and studies on the relationship between reactivity and antitumor activity. Inorganica chimica acta 250 (1-2), pp. 203-218. Fulltext not available.

Spruss, Thilo and Bernhardt, Günther (1996) Chemosensitivity of malignant melanoma models: long-term complete remission after regional hyaluronidase/vinblastine therapy. In: Arnold, Wolfgang, (ed.) Immunodeficient Animals: Models for Cancer Research. Contributions to Oncology, 51. , pp. 145-150. Fulltext not available.

Lux, Franz, Hollstein, Michael, Reile, Herta, Bernhardt, Günther and Schönenberger, Helmut (1996) Discrepancy between cytotoxicity, platinum accumulation, and DNA platination in MCF-7 breast cancer cells treated with diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and cisplatin. Biological Trace Element Research 53 (1-3), pp. 113-128. Fulltext not available.

Hafner, F., Holler, E. and Angerer, E. von (1996) Effect of growth factors on estrogen receptor mediated gene expression. The Journal of Steroid Biochemistry and Molecular Biology 58 (4), pp. 385-393. Fulltext not available.

Angerer, Erwin von (1996) Entwicklungsstrategien fur Arzneistoffe zur Therapie hormonabhangiger Tumoren. Pharmazie in unserer Zeit 25 (2), pp. 74-84. Fulltext not available.

Muckenschnabel, Ingo, Bernhardt, Günther, Spruß, Thilo and Buschauer, Armin (1996) Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice. Cancer Chemother. Pharmacol 38, pp. 88-94. Fulltext not available.

Knieps, Sebastian, Dove, Stefan, Michel, Martin C., Rottmeier, Karin, Wernet, W., Bernhardt, Günther and Buschauer, Armin (1996) w -Phenyl-w -(2-pyridyl)alkyl-substituted bisguanidines are moderate neuropeptide Y antagonists. Pharm. Pharmacol. Lett. 6, pp. 27-30. Fulltext not available.

1995

Mokrosz, M. J., Strekowski, L., Kosak, W. X., Duszynska, B., Bojarski, A. J., Klodzinska, A., Czarny, A., Cegla, M. T., Deren-Wesolek, A., Chojnacka-Wojcik, E., Dove, Stefan and Mokrosz, J. L. (1995) 4,6-Di(heteroaryl)-2-(N-methylpiperazino)pyrimidines as New, Potent 5-HT2A Receptor Ligands: A Verification of the Topographic Model. Archiv der Pharmazie 328 (9), pp. 659-666. Fulltext not available.

Glaß, D., Buschauer, Armin, Tenor, H., Bartel, S., Will-Shahab, L. and Krause, E.-G. (1995) 4-(4-Guanidinobenzoyl)-2-imidazolones and related compounds: Phosphodiesterase inhibitors and novel cardiotonics with combined histamine H2 receptor agonist and PDE III inhibitor activity. Arch. Pharm. (Weinheim) 328, pp. 709-719. Fulltext not available.

Hagelüken, Astrid, Burde, Rahel, Nürnberg, Bernd, Harhammer, Rainer, Buschauer, Armin and Seifert, Roland (1995) Cationic-amphiphilic arpromidine-derived guanidines and a histamine trifluoromethyl-toluidide derivative may activate pertussis toxin-sensitive G-proteins by a receptor-independent mechanism. Naunyn Schmiedeberg's Arch. Pharmacol. 351, pp. 305-308. Fulltext not available.

Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt H., Schertl, Sabine and Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the "third generation platinum complex" [(+/-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie 328 (9), pp. 645-653. Fulltext not available.

Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt-Heinz, Schertl, Sabine and Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the $\"$ third generation platinum complex $\"$ [(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie (Weinheim, Germany) 328 (9), pp. 645-653. Fulltext not available.

Coruzzi, Gabriela, Adami, Maristella, Pozzoli, Cristina, Buschauer, Armin and Bertaccini, Giulio (1995) Different activities of impromidine and related phenyl-(pyridylalkyl)guanidines at cardiac and gastric H_2 receptors. Inflamm. Res. 44 (Supl.), pp. 108-109. Fulltext not available.

Dove, Stefan, Kühne, R. and Schunack, W. (1995) H1 agonistic 2-heteroaryl and 2-phenylhistamines: CoMFA and possible receptor binding sites. In: Sanz, F. and Giraldo, J. and Manaut, F., (eds.) QSAR and Molecular Modelling: Concepts, Computational Tools and Biological Applications. J. R. Prous Science Publ., Barcelona, 427 - 432. Fulltext not available.

Felix, Stefan B., Buschauer, Armin and Baumann, Gert (1995) Haemodynamic profile of new H_2-receptor agonists in congestive heart failure. European Journal Of Clinical Investigation 25 (Suppl.), pp. 42-46. Fulltext not available.

Spruß, Thilo, Bernhardt, Günther, Schönenberger, Helmut and Schiess, Wilfried (1995) Hyaluronidase significantly enhances the efficacy of regional vinblastine chemotherapy of malignant melanoma. Journal of cancer research and clinical oncology 121 (4), pp. 193-202. Fulltext not available.

Knieps, Sebastian, Michel, Martin C., Dove, Stefan and Buschauer, Armin (1995) Non-peptide neuropeptide Y antagonists derived from the histamine H_2 agonist arpromidine: Role of the guanidine group. Bioorg. Med. Chem. Lett. 5, pp. 2065-2070. Fulltext not available.

Angerer, E. von, Biberger, C. and Leichtl, S. (1995) Studies on heterocycle-based pure estrogen antagonists. Annals of the New York Academy of Sciences 761, pp. 176-191. Fulltext not available.

Buschauer, Armin, Mohr, Rainer and Schunack, Walter (1995) Synthesis and histamine H_2-receptor antagonist activity of 4-(1-pyrazolyl)butanamides, guanidinopyrazoles, and related compounds. Arch. Pharm. (Weinheim) 328, pp. 349-358. Fulltext not available.

Gust, Ronald and Schönenberger, Helmut (1995) Third generation antitumor platinum(II) complexes of the [1-(fluoro/difluorophenyl)-2-phenylethylenediamine]platinum(II) type. Archiv der Pharmazie 328 (7-8), pp. 595-603. Fulltext not available.

1994

Angerer, E. von, Biberger, C., Holler, E., Koop, R. and Leichtl, S. (1994) 1-Carbamoylalkyl-2-phenylindoles: relationship between side chain structure and estrogen antagonism. The Journal of Steroid Biochemistry and Molecular Biology 49 (1), pp. 51-62. Fulltext not available.

Mahboobi, Siavosh, Grothus, Götz and von Angerer, Erwin (1994) 3-Substituierte 2-Phenylindole: Synthese und biologische Eigenschaften. Archiv der Pharmazie 327 (8), pp. 481-492. Fulltext not available.

Meyer, T., Koop, R., Angerer, E. von, Schönenberger, H. and Holler, E. (1994) A rapid luciferase transfection assay for transcription activation effects and stability control of estrogenic drugs in cell cultures. Journal of Cancer Research and Clinical Oncology 120 (6), pp. 359-364. Fulltext not available.

Maucher, A. and Angerer, E. von (1994) Antitumour activity of coumarin and 7-hydroxycoumarin against 7,12-dimethylbenz[a]anthracene-induced rat mammary carcinomas. Journal of cancer research and clinical oncology 120 (8), pp. 502-504. Fulltext not available.

Angerer, E. von, Kager, M. and Maucher, A. (1994) Antitumour activity of coumarin in prostate and mammary cancer models. Journal of Cancer Research and Clinical Oncology 120 Suppl, S14-S16. Fulltext not available.

Rixen, D., Neugebauer, E., Lechleuthner, A., Buschauer, Armin, Nagelschmidt, M., Thoma, S. and Rink, A. (1994) Beneficial effect of H_2-agonism and H_1-antagonism in rat endotoxic shock ? Shock 2, pp. 47-52. Fulltext not available.

Angerer, S. von, Seidl, E., Mannschreck, A., Angerer, E. von and Wiegrebe, Wolfgang (1994) Dibenzo[a,f]quinolizines: syntheses and cytostatic activity in estrogen-sensitive tumor cells. Anti-cancer drug design 9 (1), pp. 25-40.

Horn, D. W., Vollmer, G., Angerer, E. von and Schneider, M. R. (1994) Effect of the nonsteroidal antiestrogen ZK 119.010 on growth and metastasis of the EnDA endometrial carcinoma. International journal of cancer. Journal international du cancer 58 (3), pp. 426-429. Fulltext not available.

Beck, E., Hofmann, M., Bernhardt, Günther, Jäger, W., Wildt, L. and Lang, N. (1994) In vitro activity of immunoconjugates between cisplatin and an anti-CA125 monoclonal antibody on ovarian cancer cell lines. Cell biophysics 24-25, pp. 163-173. Fulltext not available.

Kleine-Tebbe, Jörg, Josties, C., Frank, G., Stalleicken, D., Buschauer, Armin and Schunack, Walter (1994) Inhibition of IgE- and non-IgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H_1-antagonist, desethoxycarbonyl-loratadine. J. Allergy Clin. Immunol. 93, pp. 494-500. Fulltext not available.

Baumann, Gert, Buschauer, Armin and Felix, Stefan B. (1994) Mögliche therapeutische Bedeutung sarkolemmaler Histamin-H_2-Rezeptoren bei Herzinsuffizienz: Hämodynamische Effekte neuer H_2-Agonisten. In: Greiling, H., (ed.) Pathobiochemie, Molekularbiologie und moderne Diagnostik kardiovaskulärer Erkrankungen. Springer, Berlin Heidelberg, pp. 104-115. Fulltext not available.

Franke, R., Dove, Stefan and Gruska, A. (1994) Physicochemical properties and drug action: alternative QSAR methods. In: Kouronnakis, P. N. and Rekka, E., (eds.) Advanced Drug Design and Development, a Medicinal Chemistry Approach. Ellis Horwood Series in Pharmaceutical Technology. Ellis Horwood, London, 43 - 97. ISBN 0-13-336793-2. Fulltext not available.

Schulze, Frank R., Alisch, Rudi A., Buschauer, Armin and Schunack, Walter (1994) Synthese und kombinierte H_1-/H_2-antagonistische Aktivität von Mepyramin- Pheniramin- und Cyclizin-Derivaten mit Cyanoguanidin-, Harnstoff- und Nitroethendiamin-Partialstrukturen. Arch. Pharm. (Weinheim) 327, pp. 455-462. Fulltext not available.

Maucher, A., Angerer, E. von, Hampl, R. and Stárka, L. (1994) The activity of epitestosterone in hormone dependent prostate tumour models. Endocrine regulations 28 (1), pp. 23-29. Fulltext not available.

1993

Maucher, A. and Angerer, E. von (1993) Antiproliferative activity of casodex (ICI 176.334) in hormone-dependent tumours. Journal of cancer research and clinical oncology 119 (11), pp. 669-674. Fulltext not available.

Spruß, Thilo, Bernhardt, Günther, Schönenberger, Helmut and Engel, Jürgen (1993) Antitumour activity of miltefosine alone and after combination with platinum complexes on MXT mouse mammary carcinoma models. Journal of cancer research and clinical oncology 119 (3), pp. 142-149.

Dove, Stefan and Schönenberger, Helmut (1993) Computer modelling of estrogenic transcriptional activation can account for different types of dose-response curves of estrogens. The Journal of Steroid Biochemistry and Molecular Biology 46 (2), pp. 163-176. Fulltext not available.

Kritzenberger, J., Bernhardt, Günther, Gust, Ronald, Pistor, Petra, Schönenberger, Helmut and Yersin, Hartmut (1993) Dichlorobis(cycloalkylamine)platinum(II) complexes. Structure activity relationship on the human MDA-MB-231 breast cancer cell line. Monatshefte fuer Chemie 124 (5), pp. 587-604.

Buschauer, Armin (1993) Diuretika - eine chemisch-pharmakologische Betrachtung. Pharm. Ztg. 138, pp. 177-188. Fulltext not available.

Stinner, B., Hasse, C., Lorenz, Wilfried, Alisch, Rudi, Schulze, Frank, Sitter, H., Lüdke, U., Buschauer, Armin and Schunack, Walter (1993) Effects of drugs combining H_1 and H_2 receptor antagonist activity on histamine release and life threatening anaphylactoid reactions in pigs. Agents Actions 38, Specia, C286-C288. Fulltext not available.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Dove, Stefan and Schönenberger, Helmut (1993) Estrogenic activity: An example of considering effectuation models in biological data interpretation and QSAR. In: Wermuth, C. G., (ed.) Trends in QSAR and Molecular Modelling. ESCOM, Leiden, 554 - 555. ISBN 978-90-72199-13-3. Fulltext not available.

Maucher, A., Kager, M. and Angerer, E. von (1993) Evaluation of the antitumour activity of coumarin in prostate cancer models. Journal of cancer research and clinical oncology 119 (3), pp. 150-154. Fulltext not available.

Franke, Rainer and Buschauer, Armin (1993) Interaction terms in Free-Wilson analysis: A QSAR of histamine H_2-agonists. In: Wermuth, C. G., (ed.) Trends in QSAR and Molecular Modelling 92. Escom, Leiden, pp. 160-162. Fulltext not available.

Hollstein, Michael, Lux, Franz, Reile, Herta, Bernhardt, Günther and Schönenberger, Helmut (1993) NAA of platinated DNA after treatment of cancer cells with new platinum complexes. Fulltext not available.

Angerer, Erwin von (1993) Platinum complexes with specific activity against hormone-dependent tumors. In: Keppler, Bernhard K., (ed.) Metal complexes in cancer chemotherapy. VHC, Weinheim, pp. 73-83. ISBN 1-560-81216-8; 3-527-28425-7. Fulltext not available.

Meyer, Thomas, Goehl, Jonas, Hohenberger, Werner, Christl, Claudia, Bernhardt, Günther, Spruss, Thilo and Schönenberger, Helmut (1993) The choice of cytostatic in hyperthermic isolated limb perfusion. Chemosensitivity testing on five human melanoma cell lines. Chirurgisches Forum fuer Experimentelle und Klinische Forschung, pp. 89-94. Fulltext not available.

1992

Angerer, Erwin von and Erber, Sebastian (1992) 3-Alkyl-2-phenylbenzo[b]thiophenes: nonsteroidal estrogen antagonists with mammary tumor inhibiting activity. The Journal of steroid biochemistry and molecular biology 41 (3-8), pp. 557-562. Fulltext not available.

Polossek, T., Ambros, R., Angerer, S. von, Brandl, G., Mannschreck, A. and Angerer, E. von (1992) 6-Alkyl-12-formylindolo[2,1-a]isoquinolines. Syntheses, estrogen receptor binding affinities, and stereospecific cytostatic activity. Journal of Medicinal Chemistry 35 (19), pp. 3537-3547. Fulltext not available.

Reile, Herta, Bernhardt, Günther, Koch, Marion, Schönenberger, Helmut, Hollstein, Michael and Lux, Franz (1992) Chemosensitivity of human MCF-7 breast cancer cells to diastereoisomeric diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and specific platinum accumulation. Cancer chemotherapy and pharmacology 30 (2), pp. 113-122.

Bernhardt, Günther, Müller, Richard, Gust, Ronald, Reile, Herta, Keller, Christoph, Spruss, Thilo and Schönenberger, Helmut (1992) Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Archiv der Pharmazie 325 (2), pp. 93-99.

Kager, M., Spruss, T., Schneider, M. R. and Angerer, E. von (1992) Dunning R3327-G prostate carcinoma of the rat: an appropriate model for drug evaluation. Journal of cancer research and clinical oncology 118 (5), pp. 334-338. Fulltext not available.

Grimm, Daniela, Hofstädter, Ferdinand, Bauer, Johann, Spruss, Thilo, Steinbach, Pia, Bernhardt, Günther and Menze, Rita (1992) Establishment and characterization of a human papillary thyroid carcinoma cell line with oxyphilic differentiation (ONCO-DG 1). Virchows Archiv. B, Cell pathology including molecular pathology 62 (2), pp. 97-104.

DiZio, J. P., Carlson, K. E., Bannochie, C. J., Welch, M. J., Angerer, E. von and Katzenellenbogen, J. A. (1992) Estrogen platinum-diamine complexes: preparation of a non-steroidal estrogen platinum-diamine complex labeled with platinum-191 and a study of its binding to the estrogen receptor in vitro and its tissue distribution in vivo. The Journal of steroid biochemistry and molecular biology 42 (3-4), pp. 363-373. Fulltext not available.

Buschauer, Armin and Baumann, Gert (1992) H_2-Agonisten des Arpromidin-Typs: Neue potentielle Arzneistoffe zur Behandlung der Herzinsuffizienz. In: Hirschelmann, R., (ed.) Entzündung und verwandte Reaktionen - Neue Erkenntnisse, neue Wirkstoffe. Jenapharm, Jena, pp. 192-203. Fulltext not available.

Baumann, Gert, Buschauer, Armin and Felix, Stefan B. (1992) Hemodynamic profile of arpromidine and its F_2-substituted derivatives in comparison to impromidine in congestive heart failure. Agents Actions Special Co, C329-C332. Fulltext not available.

Bungardt, Edwin, Buschauer, Armin, Moser, Ulrich, Schunack, Walter, Lambrecht, Günter and Mutschler, Ernst (1992) Histamine H_1-receptors mediate vasodilation in guinea-pig ileum resistance vessels: Characterization by the use of computer-assisted videomicroscopy and new selective agonists. Eur. J. Pharmacol. 221, pp. 91-98. Fulltext not available.

Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter (1992) Histamine analogues: imidazolylalkylguanidines, synthesis and in vitro pharmacology. European Journal of Medicinal Chemistry 27, pp. 27-32. Fulltext not available.

Seifert, Roland, Höer, Ariane, Offermann, Stefan, Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Seifert, Roland, Höer, Ariane, Schwaner, Ingo and Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, pp. 235-241.

Beckenlehner, Karin, Bannke, Silke, Spruss, Thilo, Bernhardt, Günther, Schönenberger, Helmut and Schiess, Wilfried (1992) Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo. Journal of cancer research and clinical oncology 118 (8), pp. 591-596.

Hirschfeld, Jürgen, Buschauer, Armin, Elz, Sigurd, Schunack, Walter, Ruat, Martial, Traiffort, Elisabeth and Schwartz, Jean-Charles (1992) Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H_2-receptor. Journal of Medicinal Chemistry 35, pp. 2231-2238. Fulltext not available.

Klein-Tebbe, Jörg, Buschauer, Armin, Friese, Andrea, Schunack, Walter and Kunkel, G. (1992) Modulation of IgE-mediated histamine release from human leukocytes by a new class of histamine H_2-agonists. Agents Actions 35, pp. 185-191. Fulltext not available.

Michel, Martin C. and Buschauer, Armin (1992) Neuropeptide Y and its antagonists. Drugs Fut. 17, pp. 39-45. Fulltext not available.

Franke, Rainer and Buschauer, Armin (1992) Quantitative structure-activity relationships in histamine H_2-agonists related to impromidine and arpromidine. European Journal of Medicinal Chemistry 27, pp. 443-448. Fulltext not available.

Bernhardt, Günther, Reile, Herta, Birnböck, Herbert, Spruss, Thilo and Schönenberger, Helmut (1992) Standardized kinetic microassay to quantify differential chemosensitivity on the basis of proliferative activity. Journal of cancer research and clinical oncology 118 (1), pp. 35-43.

Buschauer, Armin, Friese-Kimmel, Andrea, Baumann, Gert and Schunack, Walter (1992) Synthesis and histamine H_2 agonistic activity of arpromidine analogues: replacement of the pheniramine-like moiety by non-heterocyclic groups. European Journal of Medicinal Chemistry 27, pp. 321-330. Fulltext not available.

Buschauer, Armin, Lachenmayr, Friedhelm and Schunack, Walter (1992) Synthesis and histamine H_2-receptor activity of heterocyclic impromidine analogues. Pharmazie 47, pp. 86-91. Fulltext not available.

Angerer, E. von, Birnböck, H., Kager, M. and Maucher, A. (1992) The effect of a combination of zindoxifene and cisplatin on Dunning R3327-G prostatic carcinomas of the rat. Journal of cancer research and clinical oncology 118 (5), pp. 339-343. Fulltext not available.

Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter (1992) The effect of lipophilic substituents on the H_2-histaminergic activity of some close analogues of impromidine. Arch. Pharm. (Weinheim) 325, pp. 471-476. Fulltext not available.

Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter (1992) Zur Synthese von (Z)- und (E)-3-(1H-imidazol-4-yl)-2-propenamin und einigen 3-(1H-Imidazol-4-yl)propanaminen. Liebigs Ann. Chem. 1992, pp. 317-322. Fulltext not available.

Bernhardt, Günther, Gust, Ronald, Reile, Herta, vom Orde, Hans Dieter, Müller, Richard, Keller, Christoph, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas, Mannschreck, Albrecht, Range, Klaus-Jürgen and Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. II. Synthesis and preliminary testing of the enantiomeric complexes. Journal of cancer research and clinical oncology 118 (3), pp. 201-208.

Bernhardt, Günther, Gust, Ronald, Reile, Herta, vom Orde, Hans Dieter, Müller, Richard, Keller, Christoph, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas, Mannschreck, Albrecht, Range, Klaus Jürgen and Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line. Journal of cancer research and clinical oncology 118 (3), pp. 209-215.

1991

Bernhardt, Günther, Reile, Herta, Spruss, Thilo, Koch, Marion, Gust, Ronald, Schönenberger, Helmut, Hollstein, Michael, Lux, Franz and Engel, Jürgen (1991) D-17446. Drugs of the Future 16 (10), pp. 899-903.

Erber, S., Ringshandl, R. and Angerer, E. von (1991) 2-Phenylbenzo[b]furans: relationship between structure, estrogen receptor affinity and cytostatic activity against mammary tumor cells. Anti-cancer drug design 6 (5), pp. 417-426. Fulltext not available.

Knebel, N. G. and Angerer, E. von (1991) 2-Phenylindole-linked [2-(aminoalkyl)pyridine]dichloroplatinum(II): complexes with a selective action on estrogen receptor positive mammary tumors. Journal of Medicinal Chemistry 34 (7), pp. 2145-2152. Fulltext not available.

Schiller, C. D., Angerer, E. von and Schneider, M. R. (1991) 6,7-Dihydro-4H-indolones: synthesis and biological properties. Archiv der Pharmazie 324 (10), pp. 767-771. Fulltext not available.

Dove, Stefan and Franke, R. (1991) Activity data decomposition - levels, methods and principles. In: Silipo, C., (ed.) QSAR: Rational approaches in the design of bioactive compounds. Pharmacochemistry library, 16. Elsevier, Amsterdam, 37 - 40. ISBN 0-444-88839-X. Fulltext not available.

Brunner, Henri, Nerl, Georg, Angerer, Erwin von and Knebel, Norbert (1991) Antitumoraktive Platin(II)-Komplexe mit substituierten 2-Aminomethylpyridin-Liganden. Archiv der Pharmazie 324 (10), pp. 779-784. Fulltext not available.

Alisch, Rudi, Schulze, Frank, Buschauer, Armin and Schunack, Walter (1991) Arylalkylaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Schweizer Patentanmeldung 02193/91-6 (22.07.1991). Fulltext not available.

Spruß, Thilo, Bernhardt, Günther, Schickaneder, Edith and Schönenberger, Helmut (1991) Different response of murine and human mammary tumour models to a series of diastereoisomeric [1,2-bis(difluorophenyl) ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 117 (5), pp. 435-443. Fulltext not available.

Schneider, M. R., Schiller, C. D., Humm, A. and Angerer, E. von (1991) Effect of zindoxifene on experimental prostatic tumours of the rat. Journal of cancer research and clinical oncology 117 (1), pp. 33-36. Fulltext not available.

Bernhardt, Günther, Spruss, Thilo and Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, pp. 24-28.

Klein-Tebbe, Jörg, Schramm, J., Bolz, M., Gagné, H., Josties, C., Lipp, Ralph, Friese, Andrea, Stark, Holger, Zingel, Volkmar, Buschauer, Armin and Fricker, Gert (1991) Influence of histamine H_1, H_2, and H_3 agonists and antagonists on IgE mediated histamine release from human basophils. In: Ring, J. and Przbilla, B., (eds.) New Trends in Allergy III. Springer, Berlin Heidelberg, pp. 152-157. Fulltext not available.

Altman, Janina, Castrillo, Thais, Beck, Wolfgang, Bernhardt, Günther and Schönenberger, Helmut (1991) Metal complexes with biologically important ligands. 62. Platinum(II) complexes of 3-(2-aminoethoxy)estrone and -estradiol. Inorganic Chemistry 30 (21), pp. 4085-4088.

Dove, Stefan and Franke, R. (1991) Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. I. Equilibrium models and parameters of ß-adrenergic effectuation. Quantitative structure activity relationships 10 (1), pp. 16-22. Fulltext not available.

Dove, Stefan and Franke, R. (1991) Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. II. Estimation and QSAR of agonistic potency and receptor affinity in a series of ß-adrenergic phenethanolamines. Quantitative structure activity relationships 10 (1), pp. 23-31. Fulltext not available.

Nishino, Y., Schneider, M. R., Michna, H. and Angerer, E. von (1991) Pharmacological characterization of a novel oestrogen antagonist, ZK 119010, in rats and mice. The Journal of endocrinology 130 (3), pp. 409-414. Fulltext not available.

Ruat, Martial, Traiffort, E., Bouthenet, M. L., Pollard, H., Moreau, J., Schwartz, Jean-Charles, Martinez-Mir, I., Palacios, J. M., Hirschfeld, Jürgen, Buschauer, Armin, Schunack, Walter, Tertiuk, W. and Ganellin, C. Robin (1991) Reversible and irreversible labelling of H_1- and H_2-receptors using novel [^125I]probes. Agents Actions Suppl. 33, pp. 123-144. Fulltext not available.

Buschauer, Armin and Baumann, Gert (1991) Structure-activity relationships of histamine H_2-agonists, a new class of positive inotropic drugs. Agents Actions Suppl. 33, pp. 231-256. Fulltext not available.

Büyüktimkin, Servet, Buschauer, Armin and Schunack, Walter (1991) Synthese und H_1/H_2-antihistaminische Wirkung w-[2-Aryl-2,3-dihydro-4(1H)-chinazolinon-1-yl]alkyl-substituierter Harnstoffe und Cyanoguanidine. Arch. Pharm. (Weinheim) 324, pp. 291-295. Fulltext not available.

Buschauer, Armin, Lachenmayr, Friedhelm and Schunack, Walter (1991) Synthesis and histamine H_2-agonistic activity of ring-substituted phenyl analogues of impromidine. Pharmazie 46, pp. 841-845. Fulltext not available.

Dove, Stefan (1991) Theoretische Methoden in der Wirkstofforschung - Möglichkeiten und Grenzen. Medicamentum 32, pp. 196-205. Fulltext not available.

Felix, Stefan B., Buschauer, Armin and Baumann, Gert (1991) Therapeutic value of H_2-receptor stimulation in congestive heart failure. Hemodynamic effects of BU-E-76, BU-E-75 and arpromidine (BU-E-50) in comparison to impromidine. Agents Actions Suppl. 33, pp. 257-269. Fulltext not available.

Reile, Herta, Spruß, Thilo, Bernhardt, Günther, Müller, Richard, Gust, Ronald and Schönenberger, Helmut (1991) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia. Archiv der Pharmazie 324 (7), pp. 405-409.

Neugebauer, Edmund and Buschauer, Armin (1991) Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels zur Behandlung des Sepsis-Syndroms, des Sepsis-like Syndroms und des septischen Schocks. Deutsche Patentanmeldung P 41 19 696.1 (14.6.1991); Offenlegungsschrift DE 41 19 696 A 1 (17.12.1992); PCT Internat. Veröffentlichung WO 92/22295 (23.12.1992). Fulltext not available.

1990

Angerer, E. von, Knebel, N., Kager, M. and Ganss, B. (1990) 1-(aminoalkyl)-2-phenylindoles as novel pure estrogen antagonists. Journal of medicinal chemistry 33 (9), pp. 2635-2640. Fulltext not available.

Erber, Sebastian and Angerer, Erwin von (1990) 2-phenylindole-linked nitroimidazoles as potential radiosensitizers for estrogen receptor positive tumors. Archiv der Pharmazie 323 (9), pp. 591-594. Fulltext not available.

Schiller, Claus D., Schneider, Martin R. and Angerer, Erwin von (1990) 3-(Cyclohexenonyl)-4-(4-hydroxyphenyl)-hexanes: antiandrogenes derived from the estrogen hexestrol. Archiv der Pharmazie 323 (7), pp. 417-420. Fulltext not available.

Mörsdorf, Peter, Engler, Heidrun, Schickaneder, Helmut, Buschauer, Armin, Schunack, Walter and Baumann, Gert (1990) Cardiohistaminergics - new developments in histamine H_2-agonists. Drugs of the Future 15, pp. 919-933. Fulltext not available.

Burde, Rahel, Buschauer, Armin and Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, pp. 455-461.

Reile, Herta, Birnböck, Herbert, Bernhardt, Günther, Spruß, Thilo and Schönenberger, Helmut (1990) Computerized determination of growth kinetic curves and doubling times from cells in microculture. Analytical biochemistry 187 (2), pp. 262-267.

Meindl, Wolfgang, Friese-Kimmel, Andrea, Lachenmayr, Friedhelm, Buschauer, Armin and Schunack, Walter (1990) Der Einfluß von Agonisten und Antagonisten des Histamin-H_1- und H_2-Rezeptors auf das Wachstum von Mycobacterium tuberculosis H 37 Ra. Arch. Pharm. (Weinheim) 323, pp. 267-272. Fulltext not available.

Stein, R. C., Dowsett, M., Cunningham, D. C., Davenport, J., Ford, H. T., Gazet, J. C., Angerer, E. von and Coombes, R. C. (1990) Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study. British journal of cancer 61 (3), pp. 451-453. Fulltext not available.

Bednarski, P. J., Gust, R., Spruss, T., Knebel, N., Otto, A., Farbel, M., Koop, R., Holler, E., Angerer, E. von and Schönenberger, H. (1990) Platinum compounds with estrogen receptor affinity. Cancer treatment reviews 17 (2-3), pp. 221-231. Fulltext not available.

Ruat, Martial, Traiffort, Elisabeth, Bouthenet, M. L., Schwartz, Jean-Charles, Hirschfeld, Jürgen, Buschauer, Armin and Schunack, Walter (1990) Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H_2-receptor. Proc. Natl. Acad. Sci. USA 87, pp. 1658-1662. Fulltext not available.

Birnböck, H. and Angerer, E. von (1990) Sulfate derivatives of 2-phenylindoles as novel steroid sulfatase inhibitors. An in vitro study on structure-activity-relationship. Biochemical pharmacology 39 (11), pp. 1709-1713. Fulltext not available.

Erber, S., Birnböck, H. and Angerer, E. von (1990) Synthesis and biological properties of a 1-(6-aziridinylhexyl)-2-phenylindole, a potential fluorescence label for estrogen receptors. Archiv der Pharmazie 323 (8), pp. 459-463. Fulltext not available.

Reile, Herta, Spruß, Thilo, Müller, Richard, Gust, Ronald, Bernhardt, Günther, Schönenberger, Helmut and Engel, Jürgen (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes, III: Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 323 (5), pp. 301-306.

Reile, Herta, Müller, Richard, Gust, Ronald, Laske, Reiner, Krischke, Walter, Bernhardt, Günther, Spruss, Thilo, Jennerwein, Margaretha, Engel, Jürgen and Seeber, Siegfried (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line. Archiv der Pharmazie 323 (3), pp. 133-140.

vom Orde, Hans Dieter, Reile, Herta, Müller, Richard, Gust, Ronald, Bernhardt, Günther, Spruß, Thilo, Schönenberger, Helmut, Burgemeister, Thomas and Mannschreck, Albrecht (1990) Tumor-inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. V. Synthesis and evaluation of enantiomeric [1,2-bis-(4-fluorophenyl)ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 116 (5), pp. 434-438.

Müller, Richard, Gust, Ronald, Bernhardt, Günther, Keller, Christoph, Schönenberger, Helmut, Seeber, Siegfried, Osieka, Reinhardt, Eastman, Alan and Jennerwein, Margaretha (1990) [DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. Journal of cancer research and clinical oncology 116 (3), pp. 237-244.

1989

Dove, Stefan (1989) Beiträge zu quantitativen Struktur-Wirkungs-Beziehungen und zur Entwicklung von Modellen der Ligand-Rezeptor-Wechselwirkung von ß-Agonisten und -Antagonisten. Habilitation, Akademie der Wissenachften der DDR. Fulltext not available.

Knebel, N., Schiller, C. D., Schneider, M. R., Schönenberger, H. and Angerer, E. von (1989) Carrier mediated action of platinum complexes on estrogen receptor positive tumors. European journal of cancer & clinical oncology 25 (2), pp. 293-299. Fulltext not available.

Buschauer, Armin (1989) Entwicklung neuer positiv inotroper Arzneistoffe: Suche nach einem Digitalisersatz. Pharm. Ztg. Wiss. 2/134, pp. 3-16. Fulltext not available.

Buschauer, Armin, Schunack, Walter, Arrang, Jean-Michel and Garbarg, Monique (1989) Histamine Receptors. In: Williams, M. and Glennon, R. A. and Timmermans, P. B. M. W. M., (eds.) Receptor Pharmacology and Function. Series Clinical Pharmacology (series Ed. M. Weiner), 13. Marcel Dekker Inc., New York, pp. 293-347. Fulltext not available.

Burde, Rahel, Seifert, Roland, Buschauer, Armin and Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, pp. 671-678.

Angerer, E. von, Birnböck, H. and Knebel, N. (1989) Platinum complexes with a selective action on estrogen receptor-positive mammary tumors. Anti-cancer drug design 4 (1), pp. 21-35. Fulltext not available.

Dove, Stefan and Franke, R. (1989) Some Problems of the Interpretation of Receptorologic Data in QSAR Work. In: Fauchere, J. L., (ed.) QSAR: Quantitative Structure-Activity Relationships in Drug Design. Progress in clinical and biological research, 291. A. R. Liss Inc., New York, 31 - 35. ISBN 0-8451-5141-X. Fulltext not available.

Büyüktimkin, Servet, Buschauer, Armin and Schunack, Walter (1989) Synthese und pharmakologische Aktivität von 2-Aryl-1-((3-(imidazol-4-yl)propyl)guanidinoalkyl)-2,3-dihydro-4(1H)-chinazolinonen. Arch. Pharm. 322, pp. 115-118. Fulltext not available.

Buschauer, Armin (1989) Synthesis and in vitro pharmacology of arpromidine and related Phenylpyridylalkylguanidines, a potential new class of positive inotropic drugs. J. Med. Chem. 32, pp. 1963-1970. Fulltext not available.

Pawlowski, Maciej, Buschauer, Armin and Schunack, Walter (1989) Synthesis of Some 9-(Aminoalkyl)-6,7-dihydropyrimido[2,1-f]purine-2,4,8-(1H,3H,9H)-triones. Arch. Pharm. (Weinheim) 322, pp. 447-449. Fulltext not available.

Mueller, Richard, Gust, Ronald, Jennerwein, Margaretha, Reile, Herta, Laske, Reiner, Krischke, Walter, Bernhardt, Günther, Spruss, Thilo, Engel, Juergen and Schönenberger, Helmut (1989) Tumor inhibiting [1,2-bis(fluorophenylethylenediamine]platinum(II) complexes. Part I. Synthesis. European Journal of Medicinal Chemistry 24 (4), pp. 341-348.

Baumann, Gert, Buschauer, Armin, Permanetter, Bernhard and Schunack, Walter (1989) Wiederherstellung der b_1-adrenergen Ansprechbarkeit bei Patienten mit Myokardinsuffizienz. In: Löllgen, H. and Just, H. and Meinertz, T., (eds.) Katecholamine in der Notfall- und Intensivmedizin. Perimed Verlag, Erlangen, pp. 28-42. Fulltext not available.

Buschauer, Armin (1989) Zur Synthese primärer w-Phenyl-w-pyridylalkylamine. Arch. Pharm. (Weinheim) 322, pp. 165-171. Fulltext not available.

1988

Bernhardt, Günther, Disteche, A., Jaenicke, Rainer, Koch, B., Lüdemann, Hans-Dietrich and Stetter, Karl Otto (1988) EFFECT OF CARBON-DIOXIDE AND HYDROSTATIC-PRESSURE ON THE PH OF CULTURE MEDIA AND THE GROWTH OF METHANOGENS AT ELEVATED-TEMPERATURE. Applied Microbiology and Biotechnology 28 (2), pp. 176-181.

Mohr, R., Buschauer, Armin and Schunack, Walter (1988) Basisch substituierte Aryloxyalkylguanidine und Analoge mit H_2-antagonistischer Wirkung. Arch. Pharm. (Weinheim) 321, pp. 221-227. Fulltext not available.

Elz, Sigurd, Kimmel, Ursula, Buschauer, Armin and Schunack, Walter (1988) Halogenderivate von N-[3-(Imidazol-4-yl)propyl]-N'-(2-phenylthioalkyl)guanidinen. Sci. Pharm. 56, pp. 229-234. Fulltext not available.

Bernhardt, Günther, Jaenicke, Rainer, Lüdemann, Hans-Dietrich, König, Helmut and Stetter, Karl Otto (1988) High Pressure Enhances the Growth Rate of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus without Extending Its Temperature Range. Applied and environmental microbiology 54 (5), pp. 1258-1261.

Buschauer, Armin (1988) Imidazolylalkylguanidine mit Diaryl-Partialstrukturen. Sci. Pharm. 56, pp. 81-88. Fulltext not available.

Baumann, Gert, Buschauer, Armin, Permanetter, Bernhard and Schunack, Walter (1988) Neue Aspekte zur Therapie der Myokardinsuffizienz. Inn. Med. 15 (Sonder, pp. 30-38. Fulltext not available.

Buschauer, Armin (1988) Phenoxy- and Phenylthioalkylguanidines - Synthesis and in vitro Pharmacology. Eur. J. Med. Chem. 23, pp. 1-6. Fulltext not available.

Knebel, N. and Angerer, E. von (1988) Platinum complexes with binding affinity for the estrogen receptor. Journal of medicinal chemistry 31 (9), pp. 1675-1679. Fulltext not available.

Jaenicke, Rainer, Bernhardt, Günther, Lüdemann, Hans-Dietrich and Stetter, Karl Otto (1988) Pressure-Induced Alterations in the Protein Pattern of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus. Applied and environmental microbiology 54 (10), pp. 2375-2380.

Bercher, H., Dove, Stefan, Ramanauskas, J. J., Repcyte, M. A., Gruendling, J., Gruska, A. and Grisk, A. (1988) Quantitative structure-activity studies on 2-alkylaminoethoxy-1,4-benzodioxanes with local anesthetic activity. Wissenschaftliche Zeitschrift der Ernst-Moritz-Arndt-Universität Greifswald, Medizinische Reihe 37 (2-3), pp. 35-37. Fulltext not available.

Büyüktimkim, Nadir and Buschauer, Armin (1988) Separation and Determination of some Amino Acid Ester Enantiomers on TLC after Derivatization with Activated (S)-(+)-Naproxen. J. Chromatogr. 450, pp. 281-283. Fulltext not available.

Buschauer, Armin (1988) Synthese positiv inotroper Substanzen: Aryloxyalkylguanidine. Arch. Pharm. (Weinheim) 321, pp. 281-285. Fulltext not available.

Buschauer, Armin (1988) Synthese positiv inotroper Substanzen: Imidazolylpropylguanidine mit Pyridin-Partialstruktur,. Arch. Pharm. (Weinheim) 321, pp. 415-418. Fulltext not available.

Büyüktimkin, Servet, Buschauer, Armin and Schunack, Walter (1988) Synthese von 1-(Aminoalkyl)-2-aryl-2,3-dihydro-4(1H)-chinazolinonen. Arch. Pharm. (Weinheim) 321, pp. 833-834. Fulltext not available.

Keller, Frank, Buschauer, Armin and Schunack, Walter (1988) Synthese, Racemattrennung und pharmakologische Wirkung chiraler H_2-Antagonisten vom Aminomethylphenoxypropylamin-Typ. Pharm. Ztg. Wiss. 1/113, pp. 48-55. Fulltext not available.

1987

Angerer, E. von and Strohmeier, J. (1987) 2-Phenylindoles. Effect of N-benzylation on estrogen receptor affinity, estrogenic properties, and mammary tumor inhibiting activity. Journal of medicinal chemistry 30 (1), pp. 131-136. Fulltext not available.

Schneider, M. R., Angerer, E. von, Höhn, W. and Sinowatz, F. (1987) Antitumor activity of antiestrogenic phenylindoles on experimental prostate tumors. European journal of cancer & clinical oncology 23 (7), pp. 1005-1015. Fulltext not available.

Buschauer, Armin (1987) Arylmethylthioalkylguanidin-Derivate, Synthese und pharmakologische Wirkung. Arzneim.-Forsch. 37, pp. 1008-1012. Fulltext not available.

Birnböck, H., Ringshandl, R. and Angerer, E. von (1987) Chromatographic analysis of the new antiestrogen zindoxifene and its metabolites in biological material. Journal of chromatography 414 (1), pp. 235-241. Fulltext not available.

Mörsdorf, Peter, Schickaneder, Helmut, Pfahlert, Volker, Engler, Heidrun, Buschauer, Armin and Schunack, Walter (1987) Guanidin-Carbonsäureester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung 37 26 381.1 (7.8.1987). , Deutsche Offenlegungsschrift DE 37 26 381 (8.2.1989); EP 0 302 164 (8.2.1989). Fulltext not available.

Bernhardt, Günther, Jaenicke, Rainer and Lüdemann, Hans-Dietrich (1987) High-Pressure Equipment for Growing Methanogenic Microorganisms on Gaseous Substrates at High Temperature. Applied and environmental microbiology 53 (8), pp. 1876-1879.

Baumann, Gert, Permanetter, Bernhard, Buschauer, Armin, Wirtzfeld, Alexander and Schunack, Walter (1987) Mögliche Bedeutung einer kardialen H_2-Rezeptor Stimulation bei Katecholamin-refraktärem Myokardversagen unterschiedlicher Ätiologie. In: Brisse, B. and Bender, F., (eds.) Autonome Innervation des Herzens - Myokardiale Hypoxie. Steinkopff-Verlag, Darmstadt, pp. 183-194. Fulltext not available.

Buschauer, Armin (1987) Synthese und pharmakologische Wirkung substituierter Imidazolylalkyl- und Thiazolylalkylguanidine. Arzneim.-Forsch. 37, pp. 1003-1007. Fulltext not available.

Buschauer, Armin (1987) Synthese von N-Benzoyl- und N-Methansulfonyl-diphenylimidocarbonat. Arch. Pharm. (Weinheim) 320, pp. 377-378. Fulltext not available.

Strohmeier, J. and Angerer, E. von (1987) Synthesis and estrogen receptor affinity of 2,3-diarylindoles. Archiv der Pharmazie 320 (5), pp. 407-417. Fulltext not available.

1986

Buschauer, Armin, Schickaneder, Helmut, Elz, Sigurd, Schunack, Walter, Szelenyi, Istvan, Baumann, Gert and Ahrens, K.-H. (1986) Guanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 35 12 084.3 (2.4.1985), Offenlegungsschrift DE 35 12 084 A. Fulltext not available.

Mohr, Rainer, Buschauer, Armin and Schunack, Walter (1986) 1,3,5-Triazin-2,4-diamine und -2,4,6-triamine mit H2-antagonistischer Wirkung. Arch. Pharm. (Weinheim) 319, pp. 878-885. Fulltext not available.

Schickaneder, Helmut, Mörsdorf, Peter, Buschauer, Armin, Schunack, Walter, Engler, Heidrun, Vergin, Hartmut and Ahrens, K.-H. (1986) 1,4-Dihydropyridinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 36 21 104.4 (24.6.1986), Offenlegungsschrift DE 36 21 104 A 1 (7.1.1988).. Fulltext not available.

Angerer, Erwin von and Prekajac, Jelica (1986) Benzo[a]carbazole derivatives. Synthesis, estrogen receptor binding affinities, and mammary tumor inhibiting activity. Journal of medicinal chemistry 29 (3), pp. 380-386. Fulltext not available.

Dove, Stefan, Koch, A. and Franke, R. (1986) Comparative QSAR Studies in a Series of 4-(Imidazol-2'-yl)phenoxypropanolamines and Pyrid-2-yloxypropanolamines with Antihypertensive, Vasodilating and ß-Blocking Properties. Acta Pharmaceutica Jugoslavica 36 (2), pp. 119-128. Fulltext not available.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. PhD, Regensburg, Universität.

Buschauer, Armin, Schunack, Walter, Baumann, Gert and Ahrens, K.-H. (1986) Neue Imidazolylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 36 31 334.3 (15.9.1986), Offenlegungsschrift DE 36 31 334 A1 (17.3.1988).. Fulltext not available.

Schneider, M. R., Angerer, E. von, Prekajac, J. and Brade, W. P. (1986) Studies on the mammary tumor-inhibiting effects of diethylstilbestrol and its mono- and diphosphate. Journal of cancer research and clinical oncology 111 (2), pp. 110-114. Fulltext not available.

Buschauer, Armin, Krämer, Irene and Schunack, Walter (1986) Synthese und H_2-antagonistische Wirkung 3-(3-piperidinomethyl-phenoxy)propyl-substituierter Kohlensäurederivate und Analoge. Arch. Pharm. (Weinheim) 319, pp. 434-443. Fulltext not available.

1985

Angerer, Erwin von, Prekajac, Jelica and Schneider, Martin R. (1985) D-15413. Drugs of the future 12 (4), pp. 1023-1026. Fulltext not available.

Angerer, Erwin von, Engel, Jürgen, Schneider, Martin R. and Sherdrick, W. (1985) D-16726. Drugs of the future 10 (4), pp. 281-285. Fulltext not available.

Buschauer, Armin (1985) 4-Aminopyrimidine mit H2-antihistaminischer Aktivität. Pharm. Ztg. Sci. Ed. 130, pp. 2067-2070. Fulltext not available.

Dove, Stefan, Coats, E., Scharfenberg, P. and Franke, R. (1985) 7-Substituted 4-Hydroxychinoline-3-carboxylic Acids as Inhibitors of Dehydrogenase Enzymes and of the Respiration of Ehrlich Ascites Tumor Cells: Multivariate Analysis and Quantitative Structure-Activity Relationships for Polar Substitutens. Journal of Medicinal Chemistry 28 (4), pp. 447-451. Fulltext not available.

Buschauer, Armin, Schickaneder, Helmut, Schunack, Walter, Szelenyi, Istvan and Ahrens, K.-H. (1985) Arylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 35 28 214.2 (6.8.1985), Offenlegungsschrift DE 35 28 214 (12.2.1987). Fulltext not available.

Barth, A., Neubert, K., Schwarz, G., Fischer, G., Dove, Stefan and Franke, R. (1985) Enzymatic Hydrolyses of Alanyl-alanine-anilides by Dipeptidyl Peptidase IV. In: Seydel, J. K., (ed.) QSAR and Strategies in the Design of Bioactive Compounds - Proceedings of the 5th European Symposium on QSAR. Verlag Chemie, Weinheim, 318 - 321. ISBN 3-527-26306-3; 0-89573-433-8. Fulltext not available.

Buschauer, Armin, Schickaneder, Helmut, Schunack, Walter, Szelenyi, Istvan and Ahrens, Kurt-Henning (1985) Heteroarylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 35 28 215.0 (6.8.1985), Offenlegungsschrift DE 35 28 215 (12.2.1987). Fulltext not available.

Schunack, Walter, Buschauer, Armin, Büyüktimkim, Servet, Dziuron, Peter, Elz, Sigurd, Gerhardt, Günter, Lebenstedt, Ernst, Lennartz, Hans-Gerd, Schwarz, Siegfried, Spitzhoff, Margrit and Steffens, Robert (1985) 2. Histamine agonists - chemistry and structure-activity relationships. In: Dahlbom, R. and Nilsson, J. L. G., (eds.) VIIIth International Symposium on Medicinal Chemistry. Swedish Pharmaceutical Press, Stockholm, pp. 169-182. Fulltext not available.

Strohmeier, J. and Angerer, E. von (1985) Hydroxy-3-(hydroxyphenyl)indoles. Relationship between structure and estrogen receptor affinity. Archiv der Pharmazie 318 (5), pp. 421-431. Fulltext not available.

Buschauer, Armin, Schickaneder, Helmut, Schunack, Walter, Elz, Sigurd, Szelenyi, Istvan, Baumann, Gert and Ahrens, K.-H. (1985) Imidazolylalkylguanidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung 85 114 205.9 (12.11.1985), Eur. Pat. Appl. EP 0 199 845 (5.11.1986). Fulltext not available.

Buschauer, Armin and Schunack, Walter (1985) Isocimetidin und Analoge. Arzneim.-Forsch. 35, pp. 1223-1224. Fulltext not available.

Buschauer, Armin, Postius, S., Szelenyi, Istvan and Schunack, Walter (1985) Isohistamine und Homologe als Bausteine von H_2-Antagonisten. Arzneim.-Forsch. 35, pp. 1025-1029. Fulltext not available.

Dove, Stefan, Kühne, R. and Franke, R. (1985) On the Application of Principal Component and Factor Analysis in QSAR Work. In: Tichy, M., (ed.) QSAR in Toxicology and Xenobiochemistry - Proceedings of a Symposium. Pharmacochem. Library, 8. Elsevier, Amsterdam, pp. 277-286. Fulltext not available.

Schwarz, G., Michel, H.-J. and Dove, Stefan (1985) Quantitative Struktur-Wirkungs-Analyse von Phosphorsäurephenylesterdiamid-Derivaten mittels Hauptkomponentenanalyse. Speziell Agrochemie : Forschung 85 (3), pp. 1-8. Fulltext not available.

Hartmann, R. W. (1985) TETRAMETHYLHES. Drugs of the Future 10, pp. 48-49. Fulltext not available.

Angerer, E. von, Prekajac, J., Schneider, M. R. and Berger, M. R. (1985) The inhibitory effect of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) on estrogen-dependent mammary tumors. Journal of cancer research and clinical oncology 110 (3), pp. 216-220. Fulltext not available.

Angerer, E. von, Prekajac, J. and Berger, M. (1985) The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors. European journal of cancer & clinical oncology 21 (4), pp. 531-537. Fulltext not available.

1984

Buschauer, Armin and Schunack, Walter (1984) (8,9-Dihydro-7H-imidazo[1,2-c][1,3]diazepin-H)-one, -5(6H)-thione und -5(6H)-ylidencyanamide. J. Heterocycl. Chem. 21, pp. 753-757. Fulltext not available.

Angerer, E. von, Prekajac, J. and Strohmeier, J. (1984) 2-Phenylindoles. Relationship between structure, estrogen receptor affinity, and mammary tumor inhibiting activity in the rat. Journal of medicinal chemistry 27 (11), pp. 1439-47. Fulltext not available.

Buschauer, Armin, Sattler, Hans-Joachim and Schunack, Walter (1984) 7,8-Dihydroimidazo[1,2-c]pyrimidin-5(6H)-one, -5(6H)-thione und -5(6H)-ylidencyanamide. Chem. Ber. 117, pp. 2597-2614. Fulltext not available.

Angerer, Erwin von, Holler, Eggehard, Schönenberger, Helmut and Schönenberger, Reinhard (1984) Antineoplastic drugs. In: Smith, Donald F., (ed.) Handbook of stereoisomers: Therapeutic drugs. CRC Press, Boca Raton, pp. 247-284. ISBN 0-8493-3421-7. Fulltext not available.

Meindl, Wolfgang R., Angerer, Erwin von, Schönenberger, Helmut and Ruckdeschel, Gotthard (1984) Benzylamines: synthesis and evaluation of antimycobacterial properties. Journal of medicinal chemistry 27 (9), pp. 1111-1118. Fulltext not available.

Lüdemann, Hans-Dietrich, Bernhardt, Günther, Jaenicke, Rainer, Koenig, Helmut and Stetter, Karl Otto (1984) Biomolecules are unstable under "black smoker" conditions. Naturwissenschaften 71 (11), pp. 583-586. Fulltext not available.

Angerer, Erwin von (1984) Development of new drugs for endocrine tumour chemotherapy. Cancer treatment reviews 11 Suppl A, pp. 147-153. Fulltext not available.

Wappes, B., Jennerwein, M., Angerer, E. von, Schönenberger, H., Engel, J., Berger, M. and Wrobel, K. H. (1984) Dichloro[1,2-bis(4-hydroxyphenyl)ethylenediamine]platinum(II) complexes: an approach to develop compounds with a specific effect on the hormone-dependent mammary carcinoma. Journal of medicinal chemistry 27 (10), pp. 1280-1286. Fulltext not available.

Angerer, Erwin von (1984) Entwicklung neuer endokrin wirksamer Tumorchemotherapeutika. In: Seeber, Siegfried and Osieka, Reinhardt and Sack, H. and Schönenberger, Helmut, (eds.) Das Resistenzproblem bei der Chemo- und Radiotherapie maligner Tumoren: Grundlagen und Klinik. Beiträge zur Onkologie, 18. Karger, Basel, pp. 83-92. ISBN 3-8055-3801-4. Fulltext not available.

Buschauer, Armin, Wegner, Kurt and Schunack, Walter (1984) Isohistamine. Arch. Pharm. (Weinheim) 317, pp. 9-14. Fulltext not available.

Franke, R., Streich, W.-J. and Dove, Stefan (1984) On the Evaluation of Structural Activity Patterns. In: Seydel, J. K., (ed.) QSAR and Strategies in the Design of Bioactive Compounds - Proceedings of the 5th European Symposium on QSAR. VCH, Weinheim, 30 - 38. ISBN 3-527-26306-3; 0-89573-433-8. Fulltext not available.

Dove, Stefan, Franke, R. and Oehme, P. (1984) QSAR in DBH-Blocking and Hypotensive Fusaric Acid Derivatives. In: Kuchar, M., (ed.) QSAR in Design of Bioactive Compounds - Proceedings of the First International Telesymposium on Medicinal Chemistry. J. R. Prous Int. Publ., Barcelona, 117 - 134. Fulltext not available.

Weidhase, R., Welker, P., Neubert, K., Dove, Stefan, Yoshimoto, T., Tsuru, D. and Barth, A. (1984) Similarities of the substrate cleavage catalyzed by proline specific endopeptidase and dipeptidyl peptidase IV. Pharmazie 39 (12), pp. 835-837. Fulltext not available.

Wappes, B., Jennerwein, M., Angerer, E. von, Engel, J., Schönenberger, H., Brunner, H., Schmidt, M., Berger, M., Schmähl, D. and Seeber, S. (1984) The tumor-inhibiting effect of isomeric dichloro(diphenylethylenediamine)platinum(II) complexes. Journal of cancer research and clinical oncology 107 (1), pp. 15-20. Fulltext not available.

1983

Angerer, Erwin von and Prekajac, Jelica (1983) 2-(Hydroxyphenyl)indoles: a new class of mammary tumor-inhibiting compounds. Journal of Medicinal Chemistry 26 (1), pp. 113-116. Fulltext restricted.

Buschauer, Armin, Wegner, Kurt and Schunack, Walter (1983) 1,n-Bis(2-imidazolyl)alkane. Arch. Pharm. (Weinheim) 316, pp. 515-520. Fulltext not available.

Angerer, Erwin von and Prekajac, Jelica (1983) 2-(Hydroxyphenyl)indoles: a new class of mammary tumor inhibiting compounds. Journal of medicinal chemistry 26 (1), pp. 113-116. Fulltext not available.

Oehlke, J., Schrötter, E., Dove, Stefan, Schick, H. and Niedrich, H. (1983) Darstellung einiger 4- und 5-substituierter Pyridin-2-Carbonsäuren als Fusarsäureanaloga. Pharmazie 38 (9), pp. 591-594. Fulltext not available.

Elz, Sigurd, Buschauer, Armin, Dräger, M. and Schunack, Walter (1983) Darstellung, Eigenschaften und Kristallstruktur der N-[2-(4,5,6,7-Tetrahydro-2-benzimidazolyl)ethyl]phthalamidsäure. Z. Naturforsch. 38b, pp. 1203-1207. Fulltext not available.

Buschauer, Armin and Schunack, Walter (1983) Die Struktur des N(pi)-Methylisohistamins - Eine Richtigstellung. Arch. Pharm. (Weinheim) 316, pp. 891-894. Fulltext not available.

Franke, R., Kühne, R. and Dove, Stefan (1983) Drug Design. Dependence of hydrophobicity on solvent and structure. In: Dearden, John C., (ed.) Quantitative Approaches to Drug Design. Pharmacochemistry library, 6. Elsevier, Amsterdam, 15 - 32. ISBN 0-444-42200-5. Fulltext not available.

Oehlke, J., Schrötter, E., Piesche, L., Dove, Stefan and Niedrich, H. (1983) Kupfer-Komplexbildungskonstanten einiger Fusarsäureanaloga. Pharmazie 38 (9), pp. 624-628. Fulltext not available.

Franke, R., Schwarz, G., Dove, Stefan, Dietrich, A. and Klinger, W. (1983) Multivariate Struktur-Wirkungs-Analyse (QSWA) für Enzyminduktoren: Polychlorierte Biphenyle. Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriumsdiagnostik 122 (5), pp. 459-464. Fulltext not available.

1982

Angerer, Erwin von (1982) Effect of N,N'-diethyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines on the DMBA-induced mammary carcinoma of the rat. Journal of Medicinal Chemistry 25 (11), pp. 1374-1377. Fulltext restricted.

Angerer, Erwin von, Egginger, Guenter, Kranzfelder, Gerhard, Bernhauer, Horst and Schönenberger, Helmut (1982) N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N'-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines. Syntheses and evaluation of their mammary tumor inhibiting activity. Journal of Medicinal Chemistry 25 (7), pp. 832-837. Fulltext restricted.

Schneider, M. R., Angerer, E. von, Schönenberger, H., Michel, R. T. and Fortmeyer, H. P. (1982) 1,1,2-triphenylbut-1-enes: relationship between structure, estradiol receptor affinity, and mammary tumor inhibiting properties. Journal of medicinal chemistry 25 (9), pp. 1070-7. Fulltext not available.

Kranzfelder, G., Hartmann, R. W., Angerer, E. von, Schönenberger, H. and Bogden, A. E. (1982) 3,4-bis(3'-hydroxyphenyl)hexane--a new mammary tumor-inhibiting compound. Journal of cancer research and clinical oncology 103 (2), pp. 165-180. Fulltext not available.

Schneider, Martin R., von Angerer, Erwin and Schönenberger, Helmut (1982) 5-Acetoxy-2-(3-acetoxyphenyl)-3-ethyl-1-methyl-1H-indene: a new mammary tumor inhibiting compound. European journal of medicinal chemistry 17 (3), pp. 245-248. Fulltext not available.

Meindl, Wolfgang, von Angerer, Erwin, Ruckdeschel, Gotthard and Schönenberger, Helmut (1982) Antimykobakterielle N-Alkylbenzylamine: Synthese und Testung von 4-Aminomethyl-2-hydroxy-benzoesaure und Homologen

Antimycobacterial N-alkylbenzylamines: synthesis and testing of 4-aminomethyl-2-hydroxybenzoic acid and its homologs. Archiv der Pharmazie 315 (11), pp. 941-946. Fulltext not available.

Buschauer, Armin, Wegner, Kurt and Schunack, Walter (1982) Basisch substituierte Cimetidin-Analoge. Eur. J. Med. Chem. - Chim. Ther. 17, pp. 505-508. Fulltext not available.

Dove, Stefan, Franke, Rainer, Kern, Edgar, Schuster, Gottfried, Kochmann, Werner and Steinke, Walter (1982) Diskriminanzanalytische Untersuchungen zur antiphytoviralen Aktivität einer Serie substituierter 1,3,5-Triazine. Wissenschaftliche Zeitschrift der Karl-Marx-Universität Leipzig, Math.-Naturwiss. Reihe 31 (4), pp. 313-320. Fulltext not available.

Angerer, Erwin von (1982) Effect of N,N'-diethyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines on the 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of the rat. Journal of medicinal chemistry 25 (11), pp. 1374-1377. Fulltext not available.

Angerer, Erwin von, Egginger, Guenter, Kranzfelder, Gerhard, Bernhauer, Horst and Schönenberger, Helmut (1982) N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: syntheses and evaluation of their mammary tumor inhibiting activity. Journal of medicinal chemistry 25 (7), pp. 832-837. Fulltext not available.

Buschauer, Armin, Sattler, Hans-Joachim and Schunack, Walter (1982) Synthese von 2-(2-Aminoethyl)-4-hydroxymethyl-imidazol. Arch. Pharm. (Weinheim) 315, pp. 563-566. Fulltext not available.

1981

Dove, Stefan, Kühne, R. and Franke, R. (1981) Hauptkomponentenanalyse von Verteilungskoeffizienten. Aus dem wissenschaftlichen Leben der Pädagogischen Hochschule "N. K. Krupskaja" Halle, S. 1/2, pp. 1-8. Fulltext not available.

Bernhardt, Günther, Rudolph, Rainer and Jaenicke, Rainer (1981) Reassociation of lactic dehydrogenase from pig heart studied by cross-linking with glutaraldehyde. Zeitschrift fuer Naturforschung, C Journal of Biosciences 36C (9-10), pp. 772-777. Fulltext not available.

Schneider, M. R., Kranzfelder, G., Angerer, E. von, Schönenberger, H., Metzler, M., Michel, R. T., Fortmeyer, H. P. and Ruckdeschel, G. (1981) The tumor-inhibiting effect of diethylstilbestrol-3,4-oxide. Journal of cancer research and clinical oncology 100 (3), pp. 247-254. Fulltext not available.

1980

Hartmann, Rolf W., Kranzfelder, Gerhard, Angerer, Erwin von and Schönenberger, Helmut (1980) Antiestrogens. Synthesis and evaluation of mammary tumor inhibiting activity of 1,1,2,2-tetraalkyl-1,2 -diphenylethanes. Journal of medicinal chemistry 23 (8), pp. 841-8. Fulltext not available.

Kranzfelder, G., Schneider, M., von Angerer, E. and Schönenberger, H. (1980) Entwicklung neuer Antiostrogene vom Typ des 3,3'-Dihydroxy-alpha, beta-diathylstilbens und ihre Prufung am DMBA-induzierten, hormonabhangigen Mammacarcinom der SD-Ratte. Journal of cancer research and clinical oncology 97 (2), pp. 167-186. Fulltext not available.

Schneider, Martin, Angerer, Erwin von, Kranzfelder, Gerhard and Schönenberger, Helmut (1980) Mammatumorhemmende Antiöstrogene vom Typ des 3,3'-Dihydroxy-alpha, beta-dialkylstilbens. Archiv der Pharmazie 313 (11), pp. 919-925. Fulltext not available.

Angerer, E. von, Kranzfelder, G., Taneja, A. K. and Schönenberger, H. (1980) N,N'-Dialkylbis(dichlorophenyl)ethylenediamines and -imidazolidines: relationship between structure and estradiol receptor affinity. Journal of medicinal chemistry 23 (12), pp. 1347-1350. Fulltext not available.

Streich, W.-J., Dove, Stefan and Franke, R. (1980) On the Rational Selection of Test Series. I. Principal Component Analysis Combined with Multidimensional Mapping (PCMM Method). Journal of Medicinal Chemistry 23 (12), pp. 1452-1456. Fulltext not available.

Dove, Stefan, Streich, J. and Franke, R. (1980) On the Rational Selection of Test Series. II. Two-Dimensional Mapping of Intraclass Correlation Matrices (TMIC Method). Journal of Medicinal Chemistry 23 (12), pp. 1456-1459. Fulltext not available.

Dove, Stefan, Franke, R. and Kühne, R. (1980) Principal Component Analysis of Partition Coefficients in Different Solvent Systems. In: Knoll, J. and Darvas, F., (eds.) Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Advance in pharmacological research and practice. 3. congress of the Hungarian Pharmacological Soc., 3. Pergamon, Oxford, 247 - 255. ISBN 0080263887; 978-0080263885. Fulltext not available.

Franke, R., Barth, A., Dove, Stefan and Laass, W. (1980) Quantitative Structure-Activity Relationships (QSAR) in Piperidinoacetanilides for Different Biological Effects - Some General Aspects. Pharmazie 35 (3), pp. 181-184. Fulltext not available.

Franke, R., Streich, W.-J. and Dove, Stefan (1980) Sample Selection Methods. In: Knoll, J. and Darvas, F., (eds.) Chemical Structure - Biological Actvity Relationships: Quantitative Approaches. ADVANCES IN PHARMACOLOGICAL RESEARCH AND PRACTICE : PROCEEDINGS OF THE 3RD CONGRESS OF THE HUNGARIAN PHARMACOLOGICAL SOCIETY, BUDAPEST, 1979, 3. Akademiai Kiado, Budapest, 153 - 157. ISBN 963-05-2368-X. Fulltext not available.

Angerer, Erwin von, Taneja, Ashok K., Ringshandl, Richard and Schönenberger, Helmut (1980) Thermolyse ortho-chlorsubstituierter 1,2-Diarylethylendiamine. Liebigs Annalen der Chemie 1980 (3), pp. 409-415. Fulltext restricted.

1979

Dove, Stefan, Franke, R., Mndshojan, O. L., Shkuljev, W. A. and Chashakjan, L. W. (1979) Discriminant-Analytical Investigation on the Structural Dependence of Hyperglycemic and Hypoglycemic Activity in a Series of Substituted ortho-Toluolsulphonylthioureas and ortho-Toluolsulphonylureas. Journal of Medicinal Chemistry 22 (1), pp. 90-95. Fulltext not available.

Franke, R., Dove, Stefan and Kühne, R. (1979) Hydrophobicity and Hydrophobic Interactions I. On the Physical Nature of Aromatic Hydrophobic Substituent Constants. European journal of medicinal chemistry 14 (4), pp. 363-372. Fulltext not available.

Franke, R., Vasilev, G. N. and Dove, Stefan (1979) Relationships between Structure and Cytotoxicity of Thiourea Derivatives. Doklady Bolgarskoj Akademii Nauk (Sofia) 32 (3), pp. 369-375. Fulltext not available.

1978

Dove, Stefan (1978) Zur Anwendung einiger multivariater Verfahren auf spezielle Probleme der quantitativen Struktur-Wirkungs-Analyse. PhD, Martin-Luther-Universität Halle. Fulltext not available.

Dove, Stefan and Franke, R. (1978) Discriminant Analysis and QSAR Work. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandlungen der Akademie der Wisenschaften der DDR, 2N. Akademie-Verlag, Berlin, 257 - 262. Fulltext not available.

Dove, Stefan and Franke, R. (1978) Einige Probleme beim Einsatz der Hauptkomponentenanalyse in der QSWA. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandlungen der Akademie der Wissenschaften der DDR, 2N. Akademie-Verlag, Berlin, 321 - 326. Fulltext not available.

Laass, W., Eichler, G., Dove, Stefan, Vogt, W. E., Franke, R. and Vahle, H. (1978) First experience in the use of factor analysis on the choice of variables for regression analysis in QSAR. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandl. der AdW der DDR, 2N. Akademie-Verlag, Berlin, 267 - 271. Fulltext not available.

Rösner, T., Dove, Stefan, Schönfelder, D., Franke, R., Unger, S. and Jentsch, W. (1978) Use of a complex classification system in pattern recognition problems for the determination of structure-activity relations. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandl. der AdW der DDR, 2N. Akademie-Verlag, Berlin, 273 - 282. Fulltext not available.

1977

Dove, Stefan and Franke, R. (1977) Möglichkeiten des Einsatzes der Hauptkomponentenanalyse bei der Untersuchung von Struktur-Wirkungs-Beziehungen. Kongreß- und Tagungsberichte der MLU Halle-Wittenberg 18 (N5), pp. 24-30. Fulltext not available.

Dove, Stefan and Franke, R. (1977) Principal Component Analysis of Time-Dependent Antiinflammatory Activity of a Series of Salicylic Acid Derivatives. Kongreß- und Tagungsberichte der MLU Halle-Wittenberg 42 (R34), pp. 216-224. Fulltext not available.

Angerer, Erwin von (1977) Synthese und acetolyse des 4-brombenzolsulfonsäure-(7-norbornadienyl)methyl-esters. Tetrahedron Letters 18 (37), pp. 3245-3248. Fulltext restricted.

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