Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models

URN to cite this document:: urn:nbn:de:bvb:355-epub-109381
DOI to cite this document:: 10.5283/epub.10938

Waack, Stephan ; Keller, Oliver ; Asper, Roman ; Brodag, Thomas ; Damm, Carsten ; Fricke, Wolfgang Florian ; Surovcik, Katharina ; Meinicke, Peter ; Merkl, Rainer

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Date of publication of this fulltext: 13 Nov 2009 10:16

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Abstract

Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in speed enabling the rapid adaptation to changing environmental demands that distinguishes HGT from gene genesis, duplications or mutations. For a precise characterization, algorithms are needed that identify transfer events ...