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DNA methylation in chromatin - complexes and mechanisms

URN to cite this document:
Felle, Max
Date of publication of this fulltext: 04 Aug 2010 11:12

Abstract (English)

The DNA in the eukaryotic genome is packaged into chromatin whose basic repeating unit is the nucleosome consisting of 147bp of DNA wrapped around an octameric histone core. The histone octamer is composed of two copies of each of the four histone proteins H2A, H2B, H3 and H4. DNA methylation is an epigenetic mechanism that is involved in various important processes in the cell such as ...


Translation of the abstract (German)

Die DNA des eukaryotischen Genoms liegt in Form von Chromatin vor, dessen wiederholende Grundeinheit das Nukleosom dargestellt. Im Nukleosom ist die DNA (147bp) um ein Oktamer von basischen Proteinen, den vier Histon-Proteinen H2A, H2B, H3 und H4, gewickelt. Die DNA-Methylierung ist ein epigenetischer Mechanismus, der an verschiedenen, bedeutenden Prozesses in der Zelle, wie der Differenzierung, ...


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