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A Novel Approach to 4-Benzylisoquinolines

URN to cite this document:
urn:nbn:de:bvb:355-epub-156293
DOI to cite this document:
10.5283/epub.15629
Berger, U. ; Burgemeister, T. ; Dannhardt, G. ; Mayer, K. K. ; Wiegrebe, Wolfgang
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Date of publication of this fulltext: 01 Jul 2010 08:55


Abstract

The reaction of quinone methides with 3.4-dihydroisoquinoline or isoquinoline leads to benzylisoquinoline derivatives. NMR and ms investigations als well as chemical degradation prove that benzylation takes place at C-4 of the isoquinoline nucleus. Spectroscopic data are given for all new compounds.


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