Number of items at this level: 194.
2020
Simon, Philipp ,
Busse, David ,
Petroff, David ,
Dorn, Christoph ,
Ehmann, Lisa,
Hochstädt, Sophie,
Girrbach, Felix,
Dietrich, Arne,
Zeitlinger, Markus,
Kees, Frieder,
Kloft, Charlotte and
Wrigge, Hermann
(2020)
Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Journal of Clinical Medicine 9 (4), p. 1067.
Simon, Philipp,
Petroff, David,
Busse, David ,
Heyne, Jana,
Girrbach, Felix,
Dietrich, Arne,
Kratzer, Alexander Ludwig,
Zeitlinger, Markus,
Kloft, Charlotte,
Kees, Frieder,
Wrigge, Hermann and
Dorn, Christoph
(2020)
Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial.
Antibiotics 9 (12), p. 931.
2013
2012
Justinger, Christoph,
Schilling, Martin K.,
Kees, Martin G.,
Kauffels, Anne,
Hirschmann, Katrin,
Kopp, Berit,
Kees, Frieder K. and
Kollmar, Otto
(2012)
Penetration of moxifloxacin into liver tissue.
International journal of antimicrobial agents 39 (6), pp. 505-509.
Fulltext not available.
2011
Kees, Frieder,
Jehkul, Andreas,
Bucher, Michael,
Mair, Georg,
Kiermaier, Josef and
Grobecker, Horst
(2011)
Bioavailability of Opipramol from a Film-coated Tablet, a Sugar-coated Tablet and an Aqueous Solution in Healthy Volunteers.
Arzneimittelforschung 53 (02), pp. 87-92.
Fulltext not available.
Kellermann, Kristine,
Dertinger, Nadja,
Blobner, Manfred ,
Kees, Frieder,
Kochs, Eberhard F. and
Jungwirth, Bettina
(2011)
Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: Reduction in cerebral inflammation but without improvement in cognitive performance.
The Journal of Thoracic and Cardiovascular Surgery 141 (3), pp. 796-802.
Fulltext not available.
2010
Göttle, Martin,
Dove, Stefan,
Kees, Frieder K.,
Schlossmann, Jens ,
Geduhn, Jens,
König, Burkhard ,
Shen, Y.,
Tang, W. J. ,
Kaever, V. and
Seifert, Roland
(2010)
Citidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.
Biochemistry 49, pp. 5494-5503.
Fulltext not available.
Desch, Matthias,
Schinner, Elisabeth,
Kees, Frieder,
Hofmann, Franz,
Seifert, Roland and
Schlossmann, Jens
(2010)
Cyclic cytidine 3′,5′‐monophosphate (cCMP) signals via cGMP kinase I.
FEBS Letters 584 (18), pp. 3979-3984.
Fulltext not available.
Mathar, Ilka,
Vennekens, Rudi ,
Meissner, Marcel,
Kees, Frieder,
Van der Mieren, Gerry,
Camacho Londoño, Juan E.,
Uhl, Sebastian,
Voets, Thomas ,
Hummel, Björn,
van den Bergh, An,
Herijgers, Paul ,
Nilius, Bernd,
Flockerzi, Veit,
Schweda, Frank and
Freichel, Marc
(2010)
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
Journal of Clinical Investigation 120 (9), pp. 3267-3279.
Fulltext not available.
2009
Rupprecht, Korbinian,
Schmidt, Christoph,
Raspé, Anne,
Schweda, Frank,
Shipkova, Maria,
Fischer, Wolfgang,
Bucher, Michael,
Kees, Frieder and
Faerber, Lothar
(2009)
Bioavailability of Mycophenolate Mofetil and Enteric‐Coated Mycophenolate Sodium Is Differentially Affected by Pantoprazole in Healthy Volunteers.
The Journal of Clinical Pharmacology 49 (10), pp. 1196-1201.
Fulltext not available.
Osten, Larissa,
Kubitza, Marion,
Gallagher, Anna Rachel,
Kastner, Jürgen,
Olbrich, Heike,
Vries, Uwe,
Kees, Frieder,
Lelongt, Brigitte,
Somlo, Stefan,
Omran, Heymut and
Witzgall, Ralph
(2009)
Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease.
Histochemistry and Cell Biology 132 (2), pp. 199-210.
Fulltext not available.
2008
Wagenlehner, F.M.E.,
Kees, F.,
Weidner, W.,
Wagenlehner, C. and
Naber, K.G.
(2008)
Concentrations of moxifloxacin in plasma and urine, and penetration into prostatic fluid and ejaculate, following single oral administration of 400mg to healthy volunteers.
International Journal of Antimicrobial Agents 31 (1), pp. 21-26.
Fulltext not available.
2007
2006
Kees, Frieder,
Bucher, Michael,
Schweda, Frank,
Gschaidmeier, Harald,
Burhenne, Juergen ,
Mikus, Gerd and
Faerber, Lothar
(2006)
Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers.
Therapeutic drug monitoring 28 (3), pp. 312-320.
Fulltext restricted.
Bucher, Michael,
Kees, Frieder K.,
Messmann, Barbara,
Lunz, Dirk,
Rath, Stephan,
Zelenka, Marek,
Schlitt, Hans J. and
Hobbhahn, Jonny
(2006)
Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.
European journal of pharmacology 536 (3), pp. 296-300.
Fulltext restricted.
Weinrich, Malte,
Scheingraber, Stefan,
Stremovskaia, Tatiana,
Schilling, Martin K.,
Kees, Frieder and
Pistorius, Georg A.
(2006)
Liver tissue concentrations of levofloxacin after single intravenous administration of 500mg for antibiotic prophylaxis in liver surgery.
International Journal of Antimicrobial Agents 28 (3), pp. 221-225.
Fulltext not available.
2005
Ito, Natsuho,
Ito, Taisuke,
Kromminga, Arno,
Bettermann, Albrecht,
Takigawa, Masahiro,
Kees, Frieder,
Straub, Rainer H. and
Paus, Ralf
(2005)
Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol.
The FASEB Journal 19 (10), pp. 1332-1334.
Fulltext not available.
2004
2002
Höcherl, K.,
Kammerl, M.,
Kees, F.,
Krämer, B. K.,
Grobecker, H. F. and
Kurtz, A.
(2002)
Role of renal nerves in stimulation of renin, COX-2, and nNOS in rat renal cortex during salt deficiency.
American Journal of Physiology-Renal Physiology 282 (3), F478-F484.
Fulltext not available.
2001
Höcherl, Klaus,
Wolf, Konrad,
Castrop, Hayo,
Ittner, Karl,
Bucher, Michael,
Kees, Frieder,
Grobecker, Horst and
Kurtz, Armin
(2001)
Renocortical expression of renin and of cyclooxygenase-2 in response to angiotensin II AT 1 receptor blockade is closely coordinated but not causally linked.
Pfl�gers Archiv European Journal of Physiology 442 (6), pp. 821-827.
Fulltext not available.
2000
Lee, Dong-Ung,
Kang, So-Im,
Yoon, Soo-Hong,
Budesinsky, Milos,
Kasal, Alexander,
Mayer, Klaus K. and
Wiegrebe, Wolfgang
(2000)
A New Steroidal Alkaloid from the Roots of Cynanchum caudatum.
Planta Medica 66 (5), pp. 480-482.
Fulltext not available.
Ittner, K.P.,
Zimmermann, M.,
Bucher, M.,
Gessele, W.,
Kees, F.,
Krämer, B.K. and
Grobecker, H.F.
(2000)
The effect of urapidil and ramipril on hyperglycemia in streptozotocin diabetic rats.
Naunyn-Schmiedeberg's Archives of Pharmacology 361 (1), pp. 92-97.
Fulltext not available.
1996
1995
Iwasa, K.,
Kondoh, Y.,
Kamigauchi, M.,
Lee, D. U.,
Tanner, U. and
Wiegrebe, Wolfgang
(1995)
Effects of Pyrogallol on O-Methylation of Dopamine and Salsolinol.
Phytochemistry 38 (2), pp. 335-342.
Fulltext not available.
1994
Kamigauchi, M.,
Noda, Y.,
Iwasa, K.,
Nishijo, Z.,
Ishida, T.,
In, Y. and
Wiegrebe, Wolfgang
(1994)
Crystal Structure of (-)-Corycavinium(+)-10-Camphorsulfonate, a Biosynthetic Intermediate to Hexahydrobenzo[c]phenanthridine Alkaloids.
Helvetica Chimica Acta 77, pp. 243-251.
Mahboobi, Siavosh,
Karcher, A.,
Grothus, Götz,
Wagner, W. and
Wiegrebe, Wolfgang
(1994)
Removal of the Pyrrolidine Substituent by Dehydrogenation of 4-Pyrrolidin-2-yl-3,4-dihydro- and 1,2,3,4-tetrahydroisoquinolines.
Archiv der Pharmazie 327, pp. 417-428.
1993
Iwasa, K.,
Kamigauchi, M.,
Saiki, K.,
Takao, N. and
Wiegrebe, Wolfgang
(1993)
O-Methylating Enzymes of Dopamine and Dopamine Derived Tetrahydroisoquinoline, Salsolinol.
Phytochemistry 32, pp. 1443-1448.
1992
Angerer, S. von,
Brandl, G.,
Mannschreck, Albrecht,
Weimar, C. and
Wiegrebe, Wolfgang
(1992)
Dibenzo[a,g]quinolizin-8-ones: synthesis, estrogen receptor affinities, and cytostatic activity.
Anti-Cancer Drug Design 7, pp. 351-363.
1991
Müller, K.,
Seidel, M.,
Braun, C.,
Ziereis, K. and
Wiegrebe, Wolfgang
(1991)
Dithranol, Glucose-6-phosphate Dehydrogenase Inhibition and Active Oxygen Species.
Arzneimittel-Forschung 41 (11), pp. 1176-1181.
Bonnekoh, B.,
Tanzer, H.,
Seidel, M.,
Geisel, J.,
Merk, H. F.,
Mahrle, G. and
Wiegrebe, Wolfgang
(1991)
Structure-Function Relationship of New Anthralin Derivatives Assayed for Growth Inhibition and Cytotoxicity in Human Keratinocyte Cultures.
Archiv der Pharmazie 324, pp. 899-906.
Lee, G. S.,
Kammermeier, T.,
Kaiser, A.,
Eibler, E. and
Wiegrebe, Wolfgang
(1991)
Synthesis of Meso- and Racemic 1, 3-Diamino-1, 3-diphenylpropanes.
Archiv der Pharmazie 324, pp. 177-181.
1990
Knefeli, F.,
Mayer, K. K.,
Wiegrebe, Wolfgang,
Schlunegger, U. P. and
Lauber, R.
(1990)
Electron Impact Induced Loss of C-5/C-8 Substituents of 1,2,3,4-Tetrahydroisoquinolines, VI, Synthesis and Mass Spectrometric Fragmentation of Dihydroindole Derivatives.
Archiv der Pharmazie 323, pp. 145-155.
1989
Angerer, S. von,
Eibler, E.,
Lee, D.-U. and
Wiegrebe, Wolfgang
(1989)
Degradation of 1-Benzyl-1,2,3,4-tetrahydroisoquinolines (Laudanosine) with Ethyl chloroformate: Gedamer's Intermediate.
Scientia Pharmaceutica (Sci. Pharm.) 57, pp. 1-6.
Lee, G. S.,
Cho, Y. S.,
Shim, S. C.,
Kim, W.-J.,
Eibler, E. and
Wiegrebe, Wolfgang
(1989)
Stereospecific Synthesis of 2,3-Dimethoxynaphtho[1,2-b] indolizidine.
Archiv der Pharmazie 322, pp. 607-611.
1988
1987
Chinnasamy, P.,
Iwasa, K.,
Angerer, S. von,
Weimar, C. and
Wiegrebe, Wolfgang
(1987)
3,10-Dimethoxyprotoberberines.
Archiv der Pharmazie 320, pp. 790-798.
1986
1985
Wiegrebe, Wolfgang,
Plumier, E.,
Mayer, K. K.,
Runne, U.,
Schultz-Amling, W.,
Rosmarinowski, J.,
Safar, G. J. and
Kubka, K. D.
(1985)
Experimental Contribution to the Dithranol-Brown-Problem.
Archives of Dermatological Research 277, pp. 153-155.
1984
Wiegrebe, Wolfgang,
Retzow, A.,
Plumier, E.,
Ersoy, Nagehan,
Garbe, A.,
Faro, H.-P. and
Kunert, R.
(1984)
Dermal Absorption and Metabolism of the Antipsoriatic Drug Dithranol Triacetate.
Arzneimittel-Forschung 34(I) (1), pp. 48-51.
1983
Knefeli, F.,
Mayer, K. K.,
Poettinger, T.,
Stöber, G. and
Wiegrebe, Wolfgang
(1983)
Elektronenstoßinduzierter Verlust der Substituenten an C-5 und C-8 bei 1,2,3,4-Tetrahydroisochinolinen, 1. Mitt.: Synthese eines 4-Acetyl-pyrrolo[1,2-b]isochinolins.
Archiv der Pharmazie 316 (9), pp. 773-781.
Mayer, K. K.,
Stöber, G. and
Wiegrebe, Wolfgang
(1983)
Elektronenstoßinduzierter Verlust der Substituenten an C-5 und C-8 bei 1,2,3,4-Tetrahydroisochinolinen, 2. Mitt.: Synthese C-8-substituierter 1,2,3,4-Tetrahydroisochinoline.
Archiv der Pharmazie 316 (9), pp. 801-812.
1982
1981
Poettinger, T. and
Wiegrebe, Wolfgang
(1981)
Synthese von (+-)-14-Hydoxy-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydro-dibenzo[f,h]pyrrolo[1,2-b]isochinolin.
Archiv der Pharmazie 314 (3), pp. 240-250.
1980
1979
Budzikiewicz, H.,
Faber, L.,
Herrmann, E.-G.,
Perrollaz, F. F.,
Schlunegger, U.P . and
Wiegrebe, Wolfgang
(1979)
Vinceten, ein Benzopyrroloisochinolin-Alkaloid aus Cynanchum vincetoxicum (L.) Pers. (Asclepiadaceae).
Justus Liebigs Annalen der Chemie, pp. 1212-1231.
1978
1977
Dannhardt, G. and
Wiegrebe, Wolfgang
(1977)
9,11,12,13,13a,14-Hexahydrodibenzo(f,h)pyrrollo(1,2-b)isochinoline durch Diels-Alder-Reaktion.
Archiv der Pharmazie 310, pp. 802-810.
1976
Faber, L. and
Wiegrebe, Wolfgang
(1976)
Stereospezifische Synthese zweier 9,11,12,12,13a,14- Hexahydro-dibenzo(f,h)pyrrolo(1,2-b)isochinoline.
Helvetica Chimica Acta 59 (6), pp. 2201-2212.
1975
Wiegrebe, Wolfgang,
Rohrbach-Munz, B.,
Awe, W. and
Kirk, O.
(1975)
Synthese und Hofmann-Abbau des 1-(Diphenyl-hydroxymethyl)-2,2-dimethyl-6,7-dimethoxy-1,2,3,4-tetrahydroisochinolinium-Ions.
Helvetica Chimica Acta 58 (6), pp. 1825-1833.
1974
1973
Faber, L. and
Wiegrebe, Wolfgang
(1973)
Stereospecific Synthesis of a 9,11,12,13,13a,14-hexahydro-dibenzo(f,h)pyrrolo(1,2-b)isoquinolinealkaloid.
Helvetica Chimica Acta 56 (8), pp. 2882-2884.
1972
1971
1970
Wiegrebe, Wolfgang,
Budzikiewicz, H. and
Faber, L.
(1970)
Alkaloide aus Cynanchum vincetoxicum (L.) Pers., 3. Mitt.: 14-Hydroxy-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydro-dibenzo/f,h/-pyrrolo/1,2-b/-isochinolin.
Archiv der Pharmazie 303 (12), pp. 1009-1012.
Wiegrebe, Wolfgang,
Faber, L. and
Budzikiewicz, H.
(1970)
Synthese des (+/-)-6-Hydroxy-2,3-dimethoxy-9,11,12,13,13a,14-hexahydro-dibenzo-/f,h/-pyrrolo/1,2-b/-isochinolins.
Justus Liebigs Annalen der Chemie 733, pp. 125-140.
1969
Wiegrebe, Wolfgang,
Reinhart, H.,
Budzikiewicz, H. and
Krüger, U.
(1969)
Indanyl-isochinoline.
Tetrahedron 25, pp. 2899-2907.
Wiegrebe, Wolfgang,
Roesel, E. and
Budzikiewicz, H.
(1969)
Synthese des 6,7-Dimethoxy-3-(3,4-dimethoxy-a-hydroxybenzyl)-2-methyl-1,2,3,4-tetrahydroisochinolins.
Archiv der Pharmazie 302 (8), pp. 572-583.
1968
Wiegrebe, Wolfgang,
Sasse, D. and
Roesel, E.
(1968)
Überführung von Benzylisochinolinen in Berbinium-Salze, 5. Mitt.: Ein Vergleich des Coralyn-Ions mit dem 2,3,9,10-Tetramethoxy-5-methyl-dibenzo/b,g/-chinolizinium-Ion.
Archiv der Pharmazie 301 (1), pp. 33-38.
1967
1966
1965
1964
1963
1962
Awe, W.,
Wiegrebe, Wolfgang,
El-Shibini, H. A. M. and
Su, M. E.
(1962)
Zur Kenntnis der Vitali-Reaktion.
Naturwissenschaften 49 (23), p. 540.
Fulltext not available.
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