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Stereospecific Synthesis of 2,3-Dimethoxynaphtho[1,2-b] indolizidine

Lee, G.S., Cho, Y.S., Shim, S.C., Kim, W.-J., Eibler, E. and Wiegrebe, Wolfgang (1989) Stereospecific Synthesis of 2,3-Dimethoxynaphtho[1,2-b] indolizidine. Archiv der Pharmazie 322, pp. 607-611.

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Date of publication of this fulltext: 08 Jul 2010 04:51


(11aS)- and (11aR)-2,3-dimethoxy-naphtho[1,2-b]indolizidine (9a and 9b) were synthesized from optically pure L- and D-glutamic acid through several steps (scheme 1). All the intermediates of the route to the optical antipodes of 9 exhibit identical physical and spectral properties except the sign of the optical rotation values. The optical purity of the enantiomers of 6 was checked by 1H-NMR ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:15707
Owner only: item control page


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