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Stereospecific Synthesis of 2,3-Dimethoxynaphtho[1,2-b] indolizidine

URN to cite this document:
urn:nbn:de:bvb:355-epub-157071
DOI to cite this document:
10.5283/epub.15707
Lee, G. S. ; Cho, Y. S. ; Shim, S. C. ; Kim, W.-J. ; Eibler, E. ; Wiegrebe, Wolfgang
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Date of publication of this fulltext: 08 Jul 2010 04:51


Abstract

(11aS)- and (11aR)-2,3-dimethoxy-naphtho[1,2-b]indolizidine (9a and 9b) were synthesized from optically pure L- and D-glutamic acid through several steps (scheme 1). All the intermediates of the route to the optical antipodes of 9 exhibit identical physical and spectral properties except the sign of the optical rotation values. The optical purity of the enantiomers of 6 was checked by 1H-NMR ...

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