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A Convenient Synthesis of 14C-Anthralin

URN to cite this document:
urn:nbn:de:bvb:355-epub-158727
Huang, H.S. ; Mayer, K.K. ; Müller, K. ; Wiegrebe, Wolfgang
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Date of publication of this fulltext: 15 Jul 2010 05:49


Abstract

Anthralin [1,8-dihydroxy-9(10H)-anthracenone] is among the most widely used drugs in the topical treatment of psoriasis1). However, not much is known concerning its mode of action at the molecular level, although a variety of cellular targets have been implicated both in the main and side effects of anthralin2 ). In particular, the interaction of anthralin with proteins has long been recognized ...

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