GDNF and BDNF gene interplay in chronic tinnitus

URN to cite this document:: urn:nbn:de:bvb:355-epub-265560
DOI to cite this document:: 10.5283/epub.26556

Sand, Philipp G. ; Langguth, Berthold ; Schecklmann, Martin ; Kleinjung, Tobias

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Date of publication of this fulltext: 24 Oct 2012 10:26

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Abstract

Background Glial cell-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) play key roles in the early development of the central auditory pathway and the inner ear. Both have been successfully employed to treat experimental forms of hearing loss and are likely to operate in a broad spectrum of auditory phenotypes, including phantom perceptions of sound. We conducted a ...