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Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1

Pham, Thu-Hang, Minderjahn, Julia, Schmidl, Christian, Hoffmeister, Helen, Schmidhofer, Sandra, Chen, Wei, Längst, Gernot, Benner, Christopher and Rehli, Michael (2013) Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1. Nucleic acids research 41 (13), pp. 6391-6402.

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Date of publication of this fulltext: 09 Sep 2013 11:51

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Abstract

The transcription factor PU.1 is crucial for the development of many hematopoietic lineages and its binding patterns significantly change during differentiation processes. However, the 'rules' for binding or not-binding of potential binding sites are only partially understood. To unveil basic characteristics of PU.1 binding site selection in different cell types, we studied the binding properties ...

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Item type:Article
Date:2013
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
23658224PubMed ID
10.1093/nar/gkt355DOI
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28816
Owner only: item control page

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