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A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions

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Engelmann, Julia C. ; Spang, Rainer
License: Creative Commons Attribution 3.0
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Date of publication of this fulltext: 08 Aug 2014 09:45


microRNAs (miRNAs) are short non-coding RNAs with regulatory functions in various biological processes including cell differentiation, development and oncogenic transformation. They can bind to mRNA transcripts of protein-coding genes and repress their translation or lead to mRNA degradation. Conversely, the transcription of miRNAs is regulated by proteins including transcription factors, ...


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