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A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions

URN to cite this document:
urn:nbn:de:bvb:355-epub-305756
Engelmann, Julia C. ; Spang, Rainer
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Date of publication of this fulltext: 08 Aug 2014 09:45


Abstract

microRNAs (miRNAs) are short non-coding RNAs with regulatory functions in various biological processes including cell differentiation, development and oncogenic transformation. They can bind to mRNA transcripts of protein-coding genes and repress their translation or lead to mRNA degradation. Conversely, the transcription of miRNAs is regulated by proteins including transcription factors, ...

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