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Bibliographie der Universität Regensburg
- Universität Regensburg (208)
- Medizin (208)
- Institut für Funktionelle Genomik (208)
- Lehrstuhl für Statistische Bioinformatik (Prof. Spang) (208)
- Institut für Funktionelle Genomik (208)
- Informatik und Data Science (208)
- Fachbereich Bioinformatik (208)
- Lehrstuhl für Statistische Bioinformatik (Prof. Spang) (208)
- Fachbereich Bioinformatik (208)
- Medizin (208)
Anzahl der Einträge in dieser Kategorie: 208.
2024
Pfahler, Simon, Georg, Peter, Schill, Rudolf 
, Klever, Maren, Grasedyck, Lars, Spang, Rainer und Wettig, Tilo
(2024)
Taming numerical imprecision by adapting the KL divergence to negative probabilities.
arXiv.
Rupp, Kevin, Lösch, Andreas, Hu, Y. Linda , Nie, Chenxi, Schill, Rudolf , Klever, Maren, Pfahler, Simon, Grasedyck, Lars, Wettig, Tilo, Beerenwinkel, Niko und Spang, Rainer
(2024)
Modeling metastatic progression from cross-sectional cancer genomics data.
Bioinformatics 40 (suppl1), i140-i150.
Glehr, Gunther , Riquelme, Paloma , Kronenberg, Katharina, Lohmayer, Robert, López-Madrona, Víctor J., Kapinsky, Michael, Schlitt, Hans J. , Geissler, Edward K. , Spang, Rainer, Haferkamp, Sebastian und Hutchinson, James A.
(2024)
Restricting datasets to classifiable samples augments discovery of immune disease biomarkers.
Nature Communications 15 (1).
Huttner, Michael
(2024)
Infrastructure for digital medicine and AI enhanced pathology.
Dissertation, Universität Regensburg.
Rupp, Kevin, Schill, Rudolf , Süskind, Jonas, Georg, Peter, Klever, Maren, Lösch, Andreas, Grasedyck, Lars, Wettig, Tilo und Spang, Rainer
(2024)
Differentiated uniformization: a new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models.
Computational Statistics.
Schill, Rudolf , Klever, Maren, Rupp, Kevin, Hu, Y. Linda , Lösch, Andreas, Georg, Peter, Pfahler, Simon, Vocht, Stefan, Hansch, Stefan, Wettig, Tilo , Grasedyck, Lars und Spang, Rainer
(2024)
Reconstructing Disease Histories in Huge Discrete State Spaces.
KI - Künstliche Intelligenz.
2023
Schill, Rudolf, Klever, Maren, Lösch, Andreas, Hu, Y. Linda , Vocht, Stefan, Rupp, Kevin, Grasedyck, Lars, Spang, Rainer und Beerenwinkel, Niko
(2023)
Overcoming Observation Bias for Cancer Progression Modeling.
bioRxiv.
(Eingereicht)
Leich, E., Brodtkorb, Marianne, Schmidt, T., Altenbuchinger, Michael, Lingjærde, Ole Christian, Lockmer, S., Holte, H., Nedeva, T., Grieb, T., Sander, B., Sundström, C., Spang, Rainer, Kimby, E. und Rosenwald, A.
(2023)
Gene expression and copy number profiling of follicular lymphoma biopsies from patients treated with first-line rituximab without chemotherapy.
Leukemia & lymphoma, S. 1-11.
Volltext nicht vorhanden.
Buck, Lena, Schmidt, Tobias, Feist, Maren, Schwarzfischer, Philipp, Kube, Dieter, Oefner, Peter J. , Zacharias, Helena U., Altenbuchinger, Michael , Dettmer, Katja , Gronwald, Wolfram und Spang, Rainer
(2023)
Anomaly detection in mixed high dimensional molecular data.
Bioinformatics 39 (8), btad501.
Rösler, Wiebke, Altenbuchinger, Michael, Baeßler, Bettina, Beissbarth, Tim, Beutel, Gernot, Bock, Robert, von Bubnoff, Nikolas, Eckardt, Jan-Niklas, Foersch, Sebastian, Loeffler, Chiara M L, Middeke, Jan Moritz, Mueller, Martha-Lena, Oellerich, Thomas, Risse, Benjamin, Scherag, André, Schliemann, Christoph, Scholz, Markus, Spang, Rainer , Thielscher, Christian, Tsoukakis, Ioannis und Kather, Jakob Nikolas
(2023)
An overview and a roadmap for artificial intelligence in hematology and oncology.
Journal of cancer research and clinical oncology.
Hu, Linda, Lösch, Andreas und Spang, Rainer
(2023)
Maschinelles lernen enthüllt den verborgenen Prozess der Tumorentstehung.
Blick in die Wissenschaft : Forschungsmagazin der Universität Regensburg 31 (44/45), S. 52-53.
Volltext nicht vorhanden.
(2023)
Maschinelles lernen enthüllt den verborgenen Prozess der Tumorentstehung.
Blick in die Wissenschaft : Forschungsmagazin der Universität Regensburg 31 (44/45), S. 52-53.
Volltext nicht vorhanden.
2022
Schill, Rudolf
(2022)
Mutual Hazard Networks: Markov chain models of cancer progression.
Dissertation, Universität Regensburg.
Georg, Peter, Grasedyck, Lars, Klever, Maren, Schill, Rudolf , Spang, Rainer und Wettig, Tilo
(2022)
Low-rank tensor methods for Markov chains with applications to tumor progression models.
Journal of Mathematical Biology 86 (7).
Hassel, Jessica C., Schank, Timo E., Smetak, Heiko, Mühlbauer, Jasmin, Salzmann, Martin, Machiraju, Devayani, Menzer, Christian, Lang, Kristin, König, Laila, Haefner, Matthias F., Hülsmeyer, Ingrid, Kohler, Christian , Spang, Rainer , Enk, Alexander, Debus, Jürgen und Beckhove, Philipp
(2022)
Evaluation of radio-immunotherapy sequence on immunological responses and clinical outcomes in patients with melanoma brain metastases (ELEKTRA).
Oncoimmunology 11 (1), S. 2066609.
Schrod, Stefan, Schäfer, Andreas, Solbrig, Stefan, Lohmayer, Robert, Gronwald, Wolfram , Oefner, Peter J. , Beißbarth, Tim, Spang, Rainer , Zacharias, Helena U. und Altenbuchinger, Michael
(2022)
BITES: Balanced Individual Treatment Effect for Survival data.
arXiv.
(Eingereicht)
2021
Schilling, Hannah-Lou, Glehr, Gunther , Kapinsky, Michael, Ahrens, Norbert , Riquelme, Paloma , Cordero, Laura, Bitterer, Florian, Schlitt, Hans J. , Geissler, Edward K. , Haferkamp, Sebastian, Hutchinson, James A. und Kronenberg, Katharina
(2021)
Development of a Flow Cytometry Assay to Predict Immune Checkpoint Blockade-Related Complications.
Frontiers in Immunology 2021 (12), S. 1-12.
Zugang zum Volltext eingeschränkt.
, Kapinsky, Michael, Ahrens, Norbert , Riquelme, Paloma , Cordero, Laura, Bitterer, Florian, Schlitt, Hans J. , Geissler, Edward K. , Haferkamp, Sebastian, Hutchinson, James A. und Kronenberg, Katharina
(2021)
Development of a Flow Cytometry Assay to Predict Immune Checkpoint Blockade-Related Complications.
Frontiers in Immunology 2021 (12), S. 1-12.
Zugang zum Volltext eingeschränkt.
Richter, Julia , John, Katharina, Staiger, Annette M., Rosenwald, Andreas, Kurz, Katrin, Michgehl, Ulf, Ott, German, Franzenburg, Sören, Kohler, Christian , Finger, Jasmin, Oschlies, Ilske, Paul, Ulrike, Siebert, Reiner, Spang, Rainer , Burkhardt, Birgit und Klapper, Wolfram
(2021)
Epstein-Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features.
British journal of haematology 196 (3), S. 681-689.
Croci, G. A., Au-Yeung, R. K. H., Reinke, S., Staiger, A. M., Koch, K., Oschlies, I., Richter, J., Poeschel, V., Held, G., Loeffler, M., Trümper, L., Rosenwald, A., Ott, G., Spang, Rainer, Altmann, B., Ziepert, M. und Klapper, W.
(2021)
SPARC-positive macrophages are the superior prognostic factor in the microenvironment of diffuse large B-cell lymphoma and independent of MYC rearrangement and double-/triple-hit status.
Annals of Oncology.
Volltext nicht vorhanden.
Jachimowicz, Ron D., Klapper, Wolfram, Glehr, Gunther , Müller, Horst, Haverkamp, Heinz, Thorns, Christoph, Hansmann, Martin Leo, Möller, Peter, Stein, Harald, Rehberg, Thorsten, von Tresckow, Bastian, Reinhardt, H. C., Borchmann, Peter, Chan, Fong Chun, Spang, Rainer, Scott, David W., Engert, Andreas, Steidl, Christian, Altenbuchinger, Michael und Rosenwald, Andreas
(2021)
Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP.
Leukemia.
Linck-Paulus, Lisa , Lämmerhirt, Lisa, Völler, Daniel, Meyer, Katharina, Engelmann, Julia C. , Spang, Rainer, Eichner, Norbert, Meister, Gunter, Kuphal, Silke und Bosserhoff, Anja Katrin
(2021)
Learning from Embryogenesis—A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development.
Journal of Clinical Medicine 10 (11), S. 2259.
Zacharias, Helena U. , Altenbuchinger, Michael, Schultheiss, Ulla T., Raffler, Johannes , Kotsis, Fruzsina, Ghasemi, Sahar, Ali, Ibrahim, Kollerits, Barbara, Metzger, Marie, Steinbrenner, Inga, Sekula, Peggy , Massy, Ziad A., Combe, Christian, Kalra, Philip A., Kronenberg, Florian, Stengel, Bénédicte , Eckardt, Kai-Uwe, Köttgen, Anna, Schmid, Matthias , Gronwald, Wolfram und Oefner, Peter J.
(2021)
A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests.
American Journal of Kidney Diseases.
Volltext nicht vorhanden.
, Altenbuchinger, Michael, Schultheiss, Ulla T., Raffler, Johannes , Kotsis, Fruzsina, Ghasemi, Sahar, Ali, Ibrahim, Kollerits, Barbara, Metzger, Marie, Steinbrenner, Inga, Sekula, Peggy , Massy, Ziad A., Combe, Christian, Kalra, Philip A., Kronenberg, Florian, Stengel, Bénédicte , Eckardt, Kai-Uwe, Köttgen, Anna, Schmid, Matthias , Gronwald, Wolfram und Oefner, Peter J.
(2021)
A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests.
American Journal of Kidney Diseases.
Volltext nicht vorhanden.
Nordmo, Carmen, Glehr, Gunther, Altenbuchinger, Michael, Spang, Rainer, Ziepert, Marita, Horn, Heike, Staiger, Annette M., Ott, German, Schmitz, Norbert, Held, Gerhard, Einsele, Hermann, Topp, Max, Rosenwald, Andreas und Rauert-Wunderlich, Hilka
(2021)
Identification of a miRNA based model to detect prognostic subgroups in patients with aggressive B-cell lymphoma.
Leukemia & Lymphoma 62 (5), S. 1107-1115.
Volltext nicht vorhanden.
Taruttis-Glagoleff, Franziska
(2021)
Modeling MYC-dependent regulation of gene expression and cell metabolism in B-cell lymphomas.
Dissertation, Universität Regensburg.
Hutchinson, James A. , Kronenberg, Katharina, Riquelme, Paloma, Wenzel, Jürgen J. , Glehr, Gunther , Schilling, Hannah-Lou , Zeman, Florian, Evert, Katja, Schmiedel, Martin, Mickler, Marion, Drexler, Konstantin, Bitterer, Florian, Cordero, Laura, Beyer, Lukas Philipp, Bach, Christian, Koestler, Josef, Burkhardt, Ralph , Schlitt, Hans J., Hellwig, Dirk, Werner, Jens M., Spang, Rainer, Schmidt, Barbara, Geissler, Edward K. und Haferkamp, Sebastian
(2021)
Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis.
Nature Communications 12, S. 1439.
2020
Görtler, Franziska
(2020)
Loss-Function Learning for Digital Tissue Deconvolution.
Dissertation, Universität Regensburg.
Reinders, Jörg, Altenbuchinger, Michael, Limm, Katharina , Schwarzfischer, Philipp, Scheidt, Tamara, Strasser, Lisa, Richter, Julia, Szczepanowski, Monika, Huber, Christian G. , Klapper, Wolfram, Spang, Rainer und Oefner, Peter J.
(2020)
Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue.
Scientific Reports 10 (7876), S. 1-11.
Stämmler, Frank Michael Nikolaus
(2020)
Standardisation and optimisation techniques in gut microbiome community analysis.
Dissertation, Universität Regensburg.
Schoen, Marian, Simeth, Jakob , Heinrich, Paul, Goertler, F., Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Altenbuchinger, Michael und Spang, Rainer
(2020)
DTD: An R Package for Digital Tissue Deconvolution.
J. Comput. Biol..
Volltext nicht vorhanden.
, Heinrich, Paul, Goertler, F., Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Altenbuchinger, Michael und Spang, Rainer
(2020)
DTD: An R Package for Digital Tissue Deconvolution.
J. Comput. Biol..
Volltext nicht vorhanden.
Goertler, Franziska, Schoen, Marian, Simeth, Jakob , Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Spang, Rainer und Altenbuchinger, Michael
(2020)
Loss-Function Learning for Digital Tissue Deconvolution.
J. Comput. Biol..
Volltext nicht vorhanden.
, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Spang, Rainer und Altenbuchinger, Michael
(2020)
Loss-Function Learning for Digital Tissue Deconvolution.
J. Comput. Biol..
Volltext nicht vorhanden.
Minderjahn, Julia, Schmidt, Andreas, Fuchs, Andreas , Schill, Rudolf, Raithel, Johanna, Babina, Magda , Schmidl, C. , Gebhard, Claudia, Schmidhofer, Sandra, Mendes, Karina , Ratermann, Anna, Glatz, Dagmar, Nützel, Margit, Edinger, Matthias, Hoffmann, Petra, Spang, Rainer , Längst, Gernot, Imhof, A. und Rehli, Michael
(2020)
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.
Nat Commun 11, S. 402.
Schill, Rudolf, Solbrig, Stefan, Wettig, Tilo und Spang, Rainer
(2020)
Modelling cancer progression using Mutual Hazard Networks.
Bioinformatics 36 (1), S. 241-249.
Volltext nicht vorhanden.
(2020)
Modelling cancer progression using Mutual Hazard Networks.
Bioinformatics 36 (1), S. 241-249.
Volltext nicht vorhanden.
Klim, S. M., Amerstorfer, F., Glehr, G. , Hauer, G., Smolle, M. A., Leitner, L. , Leithner, A. und Glehr, M.
(2020)
Combined serum biomarker analysis shows no benefit in the diagnosis of periprosthetic joint infection.
International Orthopaedics 44 (12), S. 2515-2520.
Volltext nicht vorhanden.
, Hauer, G., Smolle, M. A., Leitner, L. , Leithner, A. und Glehr, M.
(2020)
Combined serum biomarker analysis shows no benefit in the diagnosis of periprosthetic joint infection.
International Orthopaedics 44 (12), S. 2515-2520.
Volltext nicht vorhanden.
2019
Arlt, A., von Bonin, F., Rehberg, Thorsten, Perez-Rubio, Paula, Engelmann, Julia C. , Limm, Katharina , Reinke, S., Dullin, C., Sun, Xueni, Specht, R., Maulhardt, M., Linke, F. , Bunt, G., Klapper, W., Vockerodt, M., Wilting, J., Pukrop, T., Dettmer, Katja, Gronwald, Wolfram, Oefner, Peter J., Spang, Rainer und Kube, D.
(2019)
High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination.
Mol Oncol.
Volltext nicht vorhanden.
, Limm, Katharina , Reinke, S., Dullin, C., Sun, Xueni, Specht, R., Maulhardt, M., Linke, F. , Bunt, G., Klapper, W., Vockerodt, M., Wilting, J., Pukrop, T., Dettmer, Katja, Gronwald, Wolfram, Oefner, Peter J., Spang, Rainer und Kube, D.
(2019)
High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination.
Mol Oncol.
Volltext nicht vorhanden.
Altenbuchinger, Michael, Zacharias, Helena, Solbrig, S., Schaefer, Andreas, Buyukozkan, M., Schultheiss, U. T. , Kotsis, F., Köttgen, Anna, Spang, Rainer, Oefner, Peter J., Krumsiek, J. und Gronwald, Wolfram
(2019)
A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study.
Scientific Reports 9 (1), S. 13954.
Staiger, A. M., Altenbuchinger, Michael, Ziepert, M., Kohler, Christian, Horn, H., Huttner, Michael , Huttl, K. S., Glehr, Gunther , Klapper, W., Szczepanowski, M., Richter, J., Stein, H., Feller, A. C., Moller, P., Hansmann, M. L., Poeschel, V., Held, G., Loeffler, M., Schmitz, N., Trumper, L., Pukrop, T., Rosenwald, A., Ott, G., Spang, Rainer , Emed Demonstrator Project, und German High Grade Non-Hodgkin’s Lymphoma Study Group (DSHNHL),
(2019)
A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL.
Leukemia 34, S. 543-552.
Volltext nicht vorhanden.
, Huttl, K. S., Glehr, Gunther , Klapper, W., Szczepanowski, M., Richter, J., Stein, H., Feller, A. C., Moller, P., Hansmann, M. L., Poeschel, V., Held, G., Loeffler, M., Schmitz, N., Trumper, L., Pukrop, T., Rosenwald, A., Ott, G., Spang, Rainer , Emed Demonstrator Project, und German High Grade Non-Hodgkin’s Lymphoma Study Group (DSHNHL),
(2019)
A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL.
Leukemia 34, S. 543-552.
Volltext nicht vorhanden.
Wagner, M., Hansel, R., Reinke, S., Richter, J., Altenbuchinger, Michael, Braumann, U. D., Spang, Rainer, Loffler, M. und Klapper, W.
(2019)
Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach.
Biol Proced Online 21, S. 13.
Perez-Rubio, Paula, Lottaz, Claudio und Engelmann, Julia C.
(2019)
FastqPuri: high-performance preprocessing of RNA-seq data.
BMC Bioinformatics 20 (1), S. 226.
Volltext nicht vorhanden.
(2019)
FastqPuri: high-performance preprocessing of RNA-seq data.
BMC Bioinformatics 20 (1), S. 226.
Volltext nicht vorhanden.
Itzel, T., Spang, Rainer, Maass, T., Munker, S., Roessler, S. , Ebert, M. P., Schlitt, Hans J., Herr, Wolfgang, Evert, Matthias und Teufel, A.
(2019)
Random gene sets in predicting survival of patients with hepatocellular carcinoma.
J. Mol. Med..
Volltext nicht vorhanden.
, Ebert, M. P., Schlitt, Hans J., Herr, Wolfgang, Evert, Matthias und Teufel, A.
(2019)
Random gene sets in predicting survival of patients with hepatocellular carcinoma.
J. Mol. Med..
Volltext nicht vorhanden.
Kleo, K., Dimitrova, L., Oker, E., Tomaszewski, N., Berg, E., Taruttis, Franziska, Engelmann, Julia C. , Schwarzfischer, Philipp, Reinders, Jörg , Spang, Rainer, Gronwald, Wolfram , Oefner, Peter J. und Hummel, Michael
(2019)
Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma.
BMC Cancer 19 (1), S. 322.
Zacharias, Helena, Altenbuchinger, Michael, Schultheiss, U. T., Samol, Claudia, Kotsis, F., Poguntke, I., Sekula, P. , Krumsiek, J., Köttgen, Anna, Spang, Rainer, Oefner, Peter J. und Gronwald, Wolfram
(2019)
A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease.
Journal of Proteome Research.
Volltext nicht vorhanden.
, Krumsiek, J., Köttgen, Anna, Spang, Rainer, Oefner, Peter J. und Gronwald, Wolfram
(2019)
A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease.
Journal of Proteome Research.
Volltext nicht vorhanden.
Schnitter, A., Kohler, Christian , Reddemann, K., Reinke, S., Thorns, C., Fend, F., Federmann, B., Moeller, P., Szczepanowski, Monika, Spang, Rainer und Klapper, Wolfram
(2019)
Therapeutic targets and microenvironment in sequential biopsies of classical Hodgkin lymphoma at diagnosis and relapse.
Journal of Hematopathology 12 (1), S. 11-17.
Ziegler, Christian, Graf, Johannes, Faderl, Stefan, Schedlbauer, Jessica, Strieder, Nicholas, Förstl, Bianca, Spang, Rainer, Bruckmann, Astrid, Merkl, Rainer , Hombach, Sonja und Kretz, Markus
(2019)
The long non-coding RNA LINC00941 and SPRR5 are novel regulators of human epidermal homeostasis.
EMBO Rep., e46612.
Volltext nicht vorhanden.
, Hombach, Sonja und Kretz, Markus
(2019)
The long non-coding RNA LINC00941 and SPRR5 are novel regulators of human epidermal homeostasis.
EMBO Rep., e46612.
Volltext nicht vorhanden.
2018
Wagener, R., Seufert, J., Raimondi, F., Bens, S., Kleinheinz, K., Nagel, I., Altmueller, J., Thiele, H., Huebschmann, D., Kohler, Christian, Nürnberg, P., Au-Yeung, R., Burkhardt, B., Horn, H., Leoncini, L., Jaffe, E. S., Ott, G., Rymkiewicz, G. , Schlesner, M. , Russell, R. B. , Klapper, W. und Siebert, R.
(2018)
The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Blood.
Volltext nicht vorhanden.
, Schlesner, M. , Russell, R. B. , Klapper, W. und Siebert, R.
(2018)
The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Blood.
Volltext nicht vorhanden.
Perez-Rubio, Paula, Lottaz, Claudio und Engelmann, Julia C.
(2018)
FastqPuri: high-performance preprocessing of RNA-seq data.
bioRxiv.
(Eingereicht)
Heinrich, Paul, Kohler, Christian , Ellmann, Lisa, Kuerner, Paul, Spang, Rainer, Oefner, Peter J. und Dettmer, Katja
(2018)
Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR.
Scientific Reports 8 (17910), S. 1-10.
Zacharias, Helena , Altenbuchinger, Michael und Gronwald, Wolfram
(2018)
Statistical Analysis of NMR Metabolic Fingerprints: Established Methods and Recent Advances.
Metabolites 8 (3).
Fröhlich, Holger, Balling, R. , Beerenwinkel, N., Kohlbacher, O., Kumar, S., Lengauer, T., Maathuis, M. H., Moreau, Y., Murphy, S. A., Przytycka, T. M. , Rebhan, M., Rost, H. , Schuppert, A. , Schwab, M., Spang, Rainer, Stekhoven, D., Sun, J., Weber, A., Ziemek, D. und Zupan, B.
(2018)
From hype to reality: data science enabling personalized medicine.
BMC Med 16 (1), S. 150.
Cho, H., Berger, B., Peng, J., Galitzine, C., Vitek, O., Beltran, P. M. J., Cristea, I. M., Görtler, Franziska, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Spang, Rainer, Altenbuchinger, Michael, Basso, R. S., Hochbaum, D., Vandin, F., Silverbush, D., Cristea, S., Yanovich, G., Geiger, T., Beerenwinkel, N., Sharan, R., Zhou, Z., Luhmann, N., Alikhan, N. F. und Achtman, M.
(2018)
Principles of Systems Biology, No. 31.
Cell Syst 7 (2), S. 133-135.
Volltext nicht vorhanden.
, Spang, Rainer, Altenbuchinger, Michael, Basso, R. S., Hochbaum, D., Vandin, F., Silverbush, D., Cristea, S., Yanovich, G., Geiger, T., Beerenwinkel, N., Sharan, R., Zhou, Z., Luhmann, N., Alikhan, N. F. und Achtman, M.
(2018)
Principles of Systems Biology, No. 31.
Cell Syst 7 (2), S. 133-135.
Volltext nicht vorhanden.
Reinke, Sarah , Richter, Julia, Fend, Falko, Feller, Alfred, Hansmann, Martin-Leo, Hüttl, Katrin, Oschlies, Ilske, Ott, German, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Altenbuchinger, Michael, Spang, Rainer und Klapper, Wolfram
(2018)
Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma—a feasibility study using full slide staining.
Virchows Archiv.
Volltext nicht vorhanden.
, Richter, Julia, Fend, Falko, Feller, Alfred, Hansmann, Martin-Leo, Hüttl, Katrin, Oschlies, Ilske, Ott, German, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Altenbuchinger, Michael, Spang, Rainer und Klapper, Wolfram
(2018)
Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma—a feasibility study using full slide staining.
Virchows Archiv.
Volltext nicht vorhanden.
Görtler, Franziska, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Spang, Rainer und Altenbuchinger, Michael
(2018)
Loss-function learning for digital tissue deconvolution.
In: Raphael, Benjamin J., (ed.)
Research in Computational Molecular Biology : 22nd Annual International Conference, RECOMB 2018, Paris, France, April 21-24, 2018, Proceedings.
Lecture Notes in Computer Science, 10812.
Springer International Publishing, Cham, S. 75-89.
ISBN 978-3-319-89929-9 ; 978-3-319-89928-2.
Volltext nicht vorhanden.
, Spang, Rainer und Altenbuchinger, Michael
(2018)
Loss-function learning for digital tissue deconvolution.
In: Raphael, Benjamin J., (ed.)
Research in Computational Molecular Biology : 22nd Annual International Conference, RECOMB 2018, Paris, France, April 21-24, 2018, Proceedings.
Lecture Notes in Computer Science, 10812.
Springer International Publishing, Cham, S. 75-89.
ISBN 978-3-319-89929-9 ; 978-3-319-89928-2.
Volltext nicht vorhanden.
Feist, M., Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, J., von Bonin, F., Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja, Gronwald, Wolfram, Reinders, Jörg, Engelmann, Julia C. , Dudek, J., Klapper, W., Trumper, L., Spang, Rainer, Oefner, Peter J. und Kube, D.
(2018)
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Nat Commun 9 (1), S. 1514.
Horn, H., Kohler, Christian, Witzig, R., Kreuz, M. , Leich, E., Klapper, W., Hummel, M., Loeffler, M., Trumper, L., Spang, Rainer, Rosenwald, A. und Ott, G.
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Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.
Haematologica.
Volltext nicht vorhanden.
, Leich, E., Klapper, W., Hummel, M., Loeffler, M., Trumper, L., Spang, Rainer, Rosenwald, A. und Ott, G.
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Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.
Haematologica.
Volltext nicht vorhanden.
Moll, Anton G.
(2018)
Semi-supervised Classification of Breast Cancer Expression Profiles Using Neural Networks.
Dissertation, Universität Regensburg.
Schill, Rudolf, Solbrig, Stefan, Wettig, Tilo und Spang, Rainer
(2018)
Modelling cancer progression using Mutual Hazard Networks.
biorxiv.org.
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Riquelme, Paloma , Haarer, Jan, Kammler, Anja, Walter, Lisa , Tomiuk, Stefan, Ahrens, Norbert , Wege, Anja K. , Goecze, Ivan, Zecher, Daniel, Banas, Bernhard , Spang, Rainer , Fändrich, Fred, Lutz, Manfred B., Sawitzki, Birgit, Schlitt, Hans J. , Ochando, Jordi , Geissler, Edward K. und Hutchinson, James A.
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TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity.
Nature Communications 9 (2858), S. 1-18.
2017
Paul, U., Richter, J., Stuhlmann-Laiesz, C., Kreuz, M. , Nagel, I., Horn, H., Staiger, A. M., Aukema, S. M., Hummel, M., Ott, G., Spang, Rainer, Rosenwald, A., Feller, A. C., Cogliatti, S., Stein, H., Hansmann, M. L., Moller, P., Szczepanowski, M., Burkhardt, B., Pfreundschuh, M., Schmitz, N., Loeffler, M., Trumper, L., Siebert, R. und Klapper, W.
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Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC.
Leuk. Lymphoma, S. 1-9.
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, Nagel, I., Horn, H., Staiger, A. M., Aukema, S. M., Hummel, M., Ott, G., Spang, Rainer, Rosenwald, A., Feller, A. C., Cogliatti, S., Stein, H., Hansmann, M. L., Moller, P., Szczepanowski, M., Burkhardt, B., Pfreundschuh, M., Schmitz, N., Loeffler, M., Trumper, L., Siebert, R. und Klapper, W.
(2017)
Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC.
Leuk. Lymphoma, S. 1-9.
Volltext nicht vorhanden.
Zacharias, Helena, Rehberg, Thorsten, Mehrl, S., Richtmann, D., Wettig, Tilo, Oefner, Peter J., Spang, Rainer, Gronwald, Wolfram und Altenbuchinger, Michael
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Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints.
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Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints.
J. Proteome Res..
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Cascione, L., Rinaldi, A., Chiappella, A., Kwee, I., Ciccone, G., Altenbuchinger, Michael, Kohler, Christian , Vitolo, U., Inghirami, G. und Bertoni, F.
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Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study.
Br J Haematol.
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, Vitolo, U., Inghirami, G. und Bertoni, F.
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Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study.
Br J Haematol.
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Altenbuchinger, Michael, Schwarzfischer, Philipp, Rehberg, Thorsten, Reinders, Jörg , Kohler, Christian , Gronwald, Wolfram , Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, Peter J. und Spang, Rainer
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Molecular signatures that can be transferred across different omics platforms.
Bioinformatics 33 (14), i333-i340.
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, Kohler, Christian , Gronwald, Wolfram , Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, Peter J. und Spang, Rainer
(2017)
Molecular signatures that can be transferred across different omics platforms.
Bioinformatics 33 (14), i333-i340.
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Oschlies, I., Kohler, Christian, Szczepanowski, Monika, Koch, K., Gontarewicz, A., Metze, D., Hillen, U., Richter, J., Spang, Rainer und Klapper, W.
(2017)
Spindle-cell variant of primary cutaneous follicle center B-cell lymphomas are germinal center B-cell lymphomas by gene expression profiling using formalin-fixed paraffin embedded specimen.
J Invest Dermatol.
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Szczepanowski, M., Lange, J., Kohler, Christian, Masque-Soler, N., Zimmermann, M., Aukema, S. M., Altenbuchinger, Michael, Rehberg, Thorsten, Mahn, F., Siebert, R., Spang, Rainer, Burkhardt, B. und Klapper, W.
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Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents.
Br. J. Haematol..
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Rohde, M., Bonn, B. R., Zimmermann, M., Lange, J., Moricke, A., Klapper, W., Oschlies, I., Szczepanowski, M., Nagel, I., Schrappe, M., Loeffler, M., Siebert, R., Reiter, A., Burkhardt, B., Altenbuchinger, Michael, Dettmer-Wilde, Katja, Engelmann, Julia C. , Gronwald, Wolfram , Oefner, Peter J. , Schwarzfischer, Philipp, Taruttis, Franziska und Spang, Rainer
(2017)
Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols.
Haematologica 102 (6), S. 1091-1098.
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, Gronwald, Wolfram , Oefner, Peter J. , Schwarzfischer, Philipp, Taruttis, Franziska und Spang, Rainer
(2017)
Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols.
Haematologica 102 (6), S. 1091-1098.
Volltext nicht vorhanden.
Feist, M., Kemper, J., Taruttis, Franziska, Rehberg, Thorsten, Engelmann, Julia C. , Gronwald, Wolfram, Hummel, Michael, Spang, Rainer und Kube, Dieter
(2017)
Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis.
International Journal of Cancer: Int. J. Cancer.
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, Gronwald, Wolfram, Hummel, Michael, Spang, Rainer und Kube, Dieter
(2017)
Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis.
International Journal of Cancer: Int. J. Cancer.
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Maliniemi, P. , Laukkanen, K., Vakeva, L., Dettmer, Katja , Lipsanen, T., Jeskanen, L., Bessede, A., Oefner, Peter J., Kadin, M. E. und Ranki, A.
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Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas.
Oncoimmunology 6 (3), e1273310.
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, Laukkanen, K., Vakeva, L., Dettmer, Katja , Lipsanen, T., Jeskanen, L., Bessede, A., Oefner, Peter J., Kadin, M. E. und Ranki, A.
(2017)
Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas.
Oncoimmunology 6 (3), e1273310.
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Schwarzfischer, Philipp, Reinders, Jörg, Dettmer, Katja , Kleo, K., Dimitrova, L., Hummel, M., Feist, M., Kube, D., Szczepanowski, M., Klapper, W., Taruttis, Franziska, Engelmann, Julia C. , Spang, Rainer, Gronwald, Wolfram und Oefner, Peter J.
(2017)
Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism.
Journal of Proteome Research 16, S. 1105-1120.
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, Kleo, K., Dimitrova, L., Hummel, M., Feist, M., Kube, D., Szczepanowski, M., Klapper, W., Taruttis, Franziska, Engelmann, Julia C. , Spang, Rainer, Gronwald, Wolfram und Oefner, Peter J.
(2017)
Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism.
Journal of Proteome Research 16, S. 1105-1120.
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Taruttis, Franziska, Feist, M., Schwarzfischer, Philipp, Gronwald, Wolfram, Kube, D., Spang, Rainer und Engelmann, Julia C.
(2017)
External calibration with Drosophila whole-cell spike-ins delivers absolute mRNA fold changes from human RNA-Seq and qPCR data.
BioTechniques 62 (2), S. 53-61.
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(2017)
External calibration with Drosophila whole-cell spike-ins delivers absolute mRNA fold changes from human RNA-Seq and qPCR data.
BioTechniques 62 (2), S. 53-61.
Volltext nicht vorhanden.
Lottaz, Claudio, Gronwald, Wolfram , Spang, Rainer und Engelmann, Julia C.
(2017)
High-Dimensional Profiling for Computational Diagnosis.
In:
Bioinformatics : Volume II: Structure, Function, and Applications.
Methods in Molecular Biology, 1526.
Springer, New York, S. 205-229.
ISBN 978-1-4939-6611-0.
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, Spang, Rainer und Engelmann, Julia C.
(2017)
High-Dimensional Profiling for Computational Diagnosis.
In:
Bioinformatics : Volume II: Structure, Function, and Applications.
Methods in Molecular Biology, 1526.
Springer, New York, S. 205-229.
ISBN 978-1-4939-6611-0.
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2016
Hosseini, H., Obradovic, M. M., Hoffmann, M., Harper, K. L., Sosa, M. S., Werner-Klein, M., Nanduri, L. K. , Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, Michael, Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., Fehm, T., Rack, B., Buchholz, S., Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, J. A. und Klein, Christoph A.
(2016)
Early dissemination seeds metastasis in breast cancer.
Nature 540, S. 552-558.
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, Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, Michael, Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., Fehm, T., Rack, B., Buchholz, S., Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, J. A. und Klein, Christoph A.
(2016)
Early dissemination seeds metastasis in breast cancer.
Nature 540, S. 552-558.
Volltext nicht vorhanden.
Dueck, A., Evers, M., Henz, S. R., Unger, K., Eichner, N., Merkl, Rainer , Berezikov, E. , Engelmann, Julia C., Weigel, D. , Wenzl, S. und Meister, Gunter
(2016)
Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants.
BMC Genomics 17 (1), S. 853.
Altenbuchinger, Michael, Rehberg, Thorsten, Zacharias, Helena, Stämmler, Frank, Dettmer, Katja , Weber, Daniela, Hiergeist, Andreas, Gessner, Andre, Holler, Ernst, Oefner, Peter J. und Spang, Rainer
(2016)
Reference point insensitive molecular data analysis.
Bioinformatics.
Pirkl, Martin Franz-Xaver
(2016)
Indirect inference of synergistic and alternative signalling of intracellular pathways.
Dissertation, Universität Regensburg.
Stämmler, Frank, Glasner, J., Hiergeist, Andreas, Holler, Ernst, Weber, Daniela, Oefner, Peter J. , Gessner, Andre und Spang, Rainer
(2016)
Adjusting microbiome profiles for differences in microbial load by spike-in bacteria.
Microbiome 4 (1), S. 28.
Moffa, Giusi, Erdmann, Gerrit, Voloshanenko, Oksana, Hundsrucker, Christian, Sadeh, Mohammad Javad, Boutros, Michael und Spang, Rainer
(2016)
Refining Pathways: A Model Comparison Approach.
PLoS One 11 (6), e0155999.
Teufel, Andreas, Itzel, Timo, Erhart, W., Brosch, M. , Wang, X. Y., Kim, Y. O., von Schoenfels, Witigo, Herrmann, A., Bruckner, S., Stickel, F., Dufour, J. F. , Chavakis, T., Hellerbrand, Claus, Spang, Rainer, Maass, Thorsten, Becker, T., Schreiber, S., Schafmayer, C., Schuppan, D. und Hampe, J.
(2016)
Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues from Patients.
Gastroenterology.
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, Wang, X. Y., Kim, Y. O., von Schoenfels, Witigo, Herrmann, A., Bruckner, S., Stickel, F., Dufour, J. F. , Chavakis, T., Hellerbrand, Claus, Spang, Rainer, Maass, Thorsten, Becker, T., Schreiber, S., Schafmayer, C., Schuppan, D. und Hampe, J.
(2016)
Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues from Patients.
Gastroenterology.
Volltext nicht vorhanden.
Schrader, A., Meyer, Katharina, Walther, N., Stolz, A., Feist, M., Hand, E., Bonin, F. von, Evers, Maurits, Kohler, Christian, Shirneshan, K., Vockerodt, M., Klapper, W., Szczepanowski, M., Murray, P. G., Bastians, H., Trümper, Lorenz, Spang, Rainer und Kube, Dieter
(2016)
Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data.
OncoTarget.
Weber, Daniela, Oefner, Peter J., Dettmer, Katja , Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Stämmler, Frank, Hahn, Joachim, Wolff, Daniel, Herr, Wolfgang und Holler, Ernst
(2016)
Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation.
Bone Marrow Transplant..
Volltext nicht vorhanden.
, Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Stämmler, Frank, Hahn, Joachim, Wolff, Daniel, Herr, Wolfgang und Holler, Ernst
(2016)
Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation.
Bone Marrow Transplant..
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Moeckel, Sylvia, Vollmann-Zwerenz, Arabel, Proescholdt, Martin A., Brawanski, Alexander, Riemenschneider, Markus J., Bogdahn, Ulrich, Bosserhoff, A. K. , Spang, Rainer und Hau, Peter
(2016)
Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro.
PLoS ONE 11 (3), e0151312.
Voelxen, N. F., Walenta, S., Proescholdt, Martin A., Dettmer, Katja , Pusch, S. und Mueller-Klieser, W.
(2016)
Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.
Frontiers in Oncology 6, S. 46.
Mönchgesang, Susann, Strehmel, Nadine, Schmidt, Stephan, Westphal, Lore, Taruttis, Franziska, Müller, Erik, Herklotz, Siska, Neumann, Steffen und Scheel, Dierk
(2016)
Natural variation of root exudates in Arabidopsis thaliana-linking metabolomic and genomic data.
Scientific Reports 6 (1).
Volltext nicht vorhanden.
2015
Loedige, Inga, Jakob, Leonhard, Treiber, Thomas, Ray, Debashish, Stotz, Mathias, Treiber, Nora, Hennig, Janosch, Cook, Kate B., Morris, Quaid, Hughes, Timothy R., Engelmann, Julia C., Krahn, Michael P. und Meister, Gunter
(2015)
The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation.
Cell Rep (Cell Reports) 13 (6), S. 1206-1220.
Evers, Maurits, Huttner, Michael, Dueck, Anne, Meister, Gunter und Engelmann, Julia C.
(2015)
miRA: adaptable novel miRNA identification in plants using small RNA sequencing data.
BMC Bioinformatics 16 (370), S. 1-10.
Pirkl, Martin, Hand, E., Kube, D. und Spang, Rainer
(2015)
Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models.
Bioinformatics.
Hochrein, Jochen, Zacharias, Helena, Taruttis, Franziska, Samol, Claudia, Engelmann, Julia C., Spang, Rainer, Oefner, Peter J. und Gronwald, Wolfram
(2015)
Data Normalization of (1)H NMR Metabolite Fingerprinting Data Sets in the Presence of Unbalanced Metabolite Regulation.
J. Proteome Res. 14 (8), S. 3217-3228.
Volltext nicht vorhanden.
Taruttis, Franziska, Spang, Rainer und Engelmann, Julia C.
(2015)
A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA).
Bioinformatics 31, S. 22.
Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian W., Aukema, Sietse M., Nagel, Inga, Richter, Julia, Siebert, Reiner, Spang, Rainer, Burkhardt, Birgit und Klapper, Wolfram
(2015)
Clinical and pathological features of Burkitt lymphoma showing expression of BCL2 - an analysis including gene expression in formalin-fixed paraffin-embedded tissue.
British Journal of Haematology = Br J Haematol 171, S. 501-508.
Engelmann, Julia C., Amann, Thomas, Ott-Rötzer, Brigitta, Nützel, Margit, Reinders, Yvonne, Reinders, Jörg, Thasler, Wolfgang E., Kristl, Theresa, Teufel, Andreas, Huber, Christian G., Oefner, Peter J., Spang, Rainer und Hellerbrand, Claus
(2015)
Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma.
PLoS Computational Biology 11 (5), S. 1-22.
Weber, Daniela, Oefner, Peter J., Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja und Holler, Ernst
(2015)
Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome.
Blood 126 (14), S. 1723-1728.
2014
Hau, Peter, Moeckel, Sylvia, Meyer, Katharina, Leukel, Petra, Heudorfer, Fabian, Seliger, Corinna, Stangl, Christina, Bogdahn, Ulrich, Proescholdt, Martin A., Brawanski, Alexander, Vollmann-Zwerenz, Arabel, Riemenschneider, Markus J., Bosserhoff, Anja-Katrin und Spang, Rainer
(2014)
Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro.
PLoS ONE 9 (9), e108632.
Winkler, Thomas W., Kutalik, Zoltan, Gorski, Mathias, Lottaz, Claudio, Kronenberg, Florian und Heid, Iris M.
(2014)
EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data.
Bioinformatics, btu621.
Volltext nicht vorhanden.
Vossenkämper, Anna, Hundsrucker, Christian, Page, Kevin, van Maurik, Andre, Sanders, Theodore J., Stagg, Andrew J., Das, Lisa und MacDonald, Thomas T.
(2014)
A CD3-Specific Antibody Reduces Cytokine Production and Alters Phosphoprotein Profiles in Intestinal Tissues From Patients With Inflammatory Bowel Disease.
The American Journal of Gastroenterology 147 (1), S. 172-183.
Volltext nicht vorhanden.
Hannus, Michael, Beitzinger, Michaela, Engelmann, Julia C., Weickert, Marie-Theresa, Spang, Rainer, Hannus, Stefan und Meister, Gunter
(2014)
siPools: highly complex but accurately defined siRNA pools eliminate off-target effects.
Nucleic Acids Research 42, S. 8049-8061.
Holler, Ernst, Butzhammer, Peter, Schmid, Karin, Hundsrucker, Christian, Koestler, Josef, Peter, Katrin, Zhu, Wentao, Sporrer, Daniela, Hehlgans, Thomas, Kreutz, Marina, Holler, Barbara, Wolff, Daniel, Edinger, Matthias, Andreesen, Reinhard, Levine, John E., Ferrara, James L., Gessner, Andre, Spang, Rainer und Oefner, Peter J.
(2014)
Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD.
Biology of Blood and Marrow Transplantation 20 (5), S. 640-645.
Volltext nicht vorhanden.
del Jel, Miriam M., Engelmann, Julia, Kunz, Manfred, Schiffner, Susanne, Kuphal, Silke und Bosserhoff, Anja
(2014)
Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations.
Pigment Cell & Melanoma Research 27, S. 678-680.
Volltext nicht vorhanden.
Dorn, Christoph, Engelmann, Julia C., Saugspier, Michael Sebastian, Koch, Andreas, Hartmann, Arndt, Spang, Rainer, Bosserhoff, Anja Katrin und Hellerbrand, Claus
(2014)
Increased expression of c-Jun in nonalcoholic fatty liver disease.
Laboratory Investigation 94, S. 394-408.
Volltext nicht vorhanden.
Dümcke, Sebastian, Bräuer, Johannes, Anchang, Benedict Nchang, Spang, Rainer, Beerenwinkel, Niko und Tresch, Achim
(2014)
Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction.
Bioinformatics 30 (3), S. 414-419.
Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian, Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, H. G., Hummel, Michael, Jaffe, Elaine S., Kueppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Loeffler, Markus, Mcleod, Roderick A., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, Rene, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Truemper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram und Siebert, Rainer
(2014)
A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.
Blood 123, S. 1187-1198.
Volltext nicht vorhanden.
Kuipers, Jack, Moffa, Giusi und Heckerman, David
(2014)
Addendum on the scoring of Gaussian directed acyclic graphical models.
Annals of Statistics 42 (4), S. 1689-1691.
(Im Druck)
Volltext nicht vorhanden.
Moffa, Giusi und Kuipers, Jack
(2014)
Sequential Monte Carlo EM for multivariate probit models.
Comp. Stats. & Data An. 72, S. 252-272.
Volltext nicht vorhanden.
2013
Schmid, Rainer, Meyer, Katharina, Spang, Rainer, Schittek, Birgit und Bosserhoff, Anja-Katrin
(2013)
YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis.
PLoS ONE 8 (12).
Sadeh, Mohammad Javad, Moffa, Giusi und Spang, Rainer
(2013)
Considering unknown unknowns: reconstruction of nonconfoundable causal relations in biological networks.
Journal of computational biology 20 (11), S. 920-932.
Volltext nicht vorhanden.
Voloshanenko, Oksana, Erdmann, Gerrit, Dubash, Taronish D., Augustin, Iris, Metzig, Marie, Moffa, Giusi, Hundsrucker, Christian, Kerr, Grainne, Sandmann, Thomas, Anchang, Benedikt, Demir, Kubilay, Boehm, Christina, Leible, Svenja, Ball, Claudia R., Glimm, Hanno, Spang, Rainer und Boutros, Michael
(2013)
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.
Nature communications 4, S. 2610.
Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian, Spang, Rainer und Klapper, Wolfram
(2013)
Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens.
Blood 122 (11), S. 1985-1986.
Schmid, Rainer, Meyer, Katharina, Spang, Rainer, Schittek, Birgit und Bosserhoff, Anja-Katrin
(2013)
Melanoma inhibitory activity promotes melanoma development through activation of YBX1.
Pigment cell & melanoma research 26 (5), S. 685-696.
Volltext nicht vorhanden.
Sadeh, Mohammad Javad
(2013)
Considering unknown unknown: reconstruction of non-confoundable causal relations in biological networks.
Dissertation, Universität Regensburg.
Walther, Neele, Ulrich, Antje, Vockerodt, Martina, von Bonin, Frederike, Klapper, Wolfram, Meyer, Katharina, Eberth, Sonja, Pukrop, Tobias, Spang, Rainer, Trümper, Lorenz und Kube, Dieter
(2013)
Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma.
The American journal of pathology 182 (4), S. 1092-1098.
Volltext nicht vorhanden.
Kelly, Gemma L, Stylianou, Julianna, Rasaiyaah, Jane, Wei, Wenbin, Thomas, Wendy, Croom-Carter, Deborah, Kohler, Christian, Spang, Rainer, Woodman, Ciaran, Kellam, Paul, Rickinson, Alan N. und Bell, Andrew I.
(2013)
Different patterns of Epstein-Barr virus latency in endemic Burkitt lymphoma (BL) lead to distinct variants within the BL-associated gene expression signature.
Journal of virology 87 (5), S. 2882-2894.
Krentz, S., Hof, J., Mendioroz, A., Vaggopoulou, R., Dörge, P., Lottaz, Claudio, Engelmann, Julia, Groeneveld, T. W. L., Körner, G., Seeger, K., Hagemeier, C., Henze, G., Eckert, C., von Stackelberg, A. und Kirschner-Schwabe, R.
(2013)
Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia.
Leukemia 27 (2), S. 295-304.
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Aryee, Martin J., Liu, Wennuan, Engelmann, Julia C., Nuhn, Philipp, Gurel, Meltem, Haffner, Michael C., Esopi, David, Irizarry, Rafael A., Getzenberg, Robert H., Nelson, William G., Luo, Jun, Xu, Jianfeng, Isaacs, William B., Bova, G. Steven und Yegnasubramanian, Srinivasan
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DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases.
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Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma.
Haematologica 99 (4), S. 726-735.
Schif, Birgit, Lennerz, Jochen K., Kohler, Christian, Bentink, Stefan, Kreuz, Markus, Melzner, Ingo, Ritz, Olga, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer und Möller, Peter
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Seliger, Corinna, Leukel, Petra, Moeckel, Sylvia, Jachnik, Birgit, Lottaz, Claudio, Kreutz, Marina, Brawanski, Alexander, Proescholdt, Martin, Bogdahn, Ulrich, Bosserhoff, Anja-Katrin, Vollmann-Zwerenz, Arabel und Hau, Peter
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2012
Hochrein, Jochen, Klein, Matthias S., Zacharias, Helena, Li, Juan, Wijffels, Gene, Schirra, Horst Joachim, Spang, Rainer, Oefner, Peter J. und Gronwald, Wolfram
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Performance evaluation of algorithms for the classification of metabolic 1H NMR fingerprints.
Journal of proteome research 11 (12), S. 6242-6251.
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Richter, Julia, Schlesner, Matthias, Hoffmann, Steve, Kreuz, Markus, Leich, Ellen, Burkhardt, Birgit, Rosolowski, Maciej, Ammerpohl, Ole, Wagener, Rabea, Bernhart, Stephan H., Lenze, Dido, Szczepanowski, Monika, Paulsen, Maren, Lipinski, Simone, Russell, Robert B., Adam-Klages, Sabine, Apic, Gordana, Claviez, Alexander, Hasenclever, Dirk, Hovestadt, Volker, Hornig, Nadine, Korbel, Jan O., Kube, Dieter, Langenberger, David, Lawerenz, Chris, Lisfeld, Jasmin, Meyer, Katharina, Picelli, Simone, Pischimarov, Jordan, Radlwimmer, Bernhard, Rausch, Tobias, Rohde, Marius, Schilhabel, Markus, Scholtysik, René, Spang, Rainer, Trautmann, Heiko, Zenz, Thorsten, Borkhardt, Arndt, Drexler, Hans G., Möller, Peter, MacLeod, Roderick A. F., Pott, Christiane, Schreiber, Stefan, Trümper, Lorenz, Loeffler, Markus, Stadler, Peter F., Lichter, Peter, Eils, Roland, Küppers, Ralf, Hummel, Michael, Klapper, Wolfram, Rosenstiel, Philip, Rosenwald, Andreas, Brors, Benedikt und Siebert, Reiner
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Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.
Nature genetics 44 (12), S. 1316-1320.
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Dolnik, Anna, Engelmann, Julia C., Scharfenberger-Schmeer, Maren, Mauch, Julian, Kelkenberg-Schade, Sabine, Haldemann, Berit, Fries, Tamara, Krönke, Jan, Kühn, Michael W. M., Paschka, Peter, Kayser, Sabine, Wolf, Stephan, Gaidzik, Verena I., Schlenk, Richard F., Rücker, Frank G., Döhner, Hartmut, Lottaz, Claudio, Döhner, Konstanze und Bullinger, Lars
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Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing.
Blood 120 (18), e83-e92.
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Beier, Christoph P., Kumar, Praveen, Meyer, Katharina, Leukel, Petra, Bruttel, Valentin, Aschenbrenner, Ines, Riemenschneider, Markus J., Fragoulis, Athanassios, Rümmele, Petra, Lamszus, Katrin, Schulz, Jörg B., Weis, Joachim, Bogdahn, Ulrich, Wischhusen, Jörg, Hau, Peter, Spang, Rainer und Beier, Dagmar
(2012)
The cancer stem cell subtype determines immune infiltration of glioblastoma.
Stem Cells and Development 21 (15), S. 2753-2761.
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Schrader, Alexandra, Bentink, Stefan, Spang, Rainer, Lenze, Dido, Hummel, Michael, Kuo, Michael, Arrand, John R., Murray, Paul G., Trümper, Lorenz, Kube, Dieter und Vockerodt, Martina
(2012)
High Myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas.
International journal of cancer 131 (4), E348-E361.
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Odoardi, Francesca, Sie, Christopher, Streyl, Kristina, Ulaganathan, Vijay K., Schläger, Christian, Lodygin, Dmitri, Heckelsmiller, Klaus, Nietfeld, Wilfried, Ellwart, Joachim, Klinkert, Wolfgang E. F., Lottaz, Claudio, Nosov, Mikhail, Brinkmann, Volker, Spang, Rainer, Lehrach, Hans, Vingron, Martin, Wekerle, Hartmut, Flügel-Koch, Cassandra und Flügel, Alexander
(2012)
T cells become licensed in the lung to enter the central nervous system.
Nature 488 (7413), S. 675-679.
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Hertwig, Falk, Meyer, Katharina, Braun, Sebastian, Ek, Sara, Spang, Rainer, Pfenninger, Cosima V., Artner, Isabella, Prost, Gaëlle, Chen, Xinbin, Biegel, Jaclyn A., Judkins, Alexander R., Englund, Elisabet und Nuber, Ulrike A.
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Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells.
Cancer research 72 (13), S. 3381-3392.
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Kohl, Stefanie M., Klein, Matthias S., Hochrein, Jochen, Oefner, Peter J., Spang, Rainer und Gronwald, Wolfram
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State-of-the art data normalization methods improve NMR-based metabolomic analysis.
Metabolomics 8 (Suppl), S. 146-160.
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Mulaw, M. A., Krause, A., Krause, A. J., Deshpande, A. J., Krause, L. F., Rouhi, A., La Starza, R., Borkhardt, A., Buske, C., Mecucci, C., Ludwig, W.-D., Lottaz, Claudio und Bohlander, S. K.
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CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.
Leukemia 26 (5), S. 1012-1019.
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Klapper, Wolfram, Kreuz, Markus, Kohler, Christian, Burkhardt, Birgit, Szczepanowski, Monika, Salaverria, Itziar, Hummel, Michael, Loeffler, Markus, Pellissery, Shoji, Woessmann, Wilhelm, Schwänen, Carsten, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Hasenclever, Dirk und Siebert, Reiner
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Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma.
Blood 119 (8), S. 1882-1887.
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Engelmann, Julia C. und Spang, Rainer
(2012)
A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions.
PloS ONE 7 (7), e40634.
Förster, Frank, Beisser, Daniela, Grohme, Markus A., Liang, Chunguang, Mali, Brahim, Siegl, Alexander Matthias, Engelmann, Julia C., Shkumatov, Alexander V., Schokraie, Elham, Müller, Tobias, Schnölzer, Martina, Schill, Ralph O., Frohme, Marcus und Dandekar, Thomas
(2012)
Transcriptome analysis in tardigrade species reveals specific molecular pathways for stress adaptations.
Bioinformatics and biology insights 6, S. 69-96.
2011
Almstetter, Martin F., Appel, Inka, Dettmer, Katja, Gruber, Michael und Oefner, Peter J.
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Comparison of two algorithmic data processing strategies for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Journal of chromatography A 1218 (39), S. 7031-7038.
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Appel, Inka, Gronwald, Wolfram und Spang, Rainer
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Estimating classification probabilities in high-dimensional diagnostic studies.
Bioinformatics 27 (18), S. 2563-2570.
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Maneck, Matthias, Schrader, Alexandra, Kube, Dieter und Spang, Rainer
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Genomic data integration using guided clustering.
Bioinformatics 27 (16), S. 2231-2238.
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Salaverria, Itziar, Philipp, Claudia, Oschlies, Ilske, Kohler, Christian, Kreuz, Markus, Szczepanowski, Monika, Burkhardt, Birgit, Trautmann, Heiko, Gesk, Stefan, Andrusiewicz, Miroslaw, Berger, Hilmar, Fey, Miriam, Harder, Lana, Hasenclever, Dirk, Hummel, Michael, Loeffler, Markus, Mahn, Friederike, Martin-Guerrero, Idoia, Pellissery, Shoji, Pott, Christiane, Pfreundschuh, Michael, Reiter, Alfred, Richter, Julia, Rosolowski, Maciej, Schwaenen, Carsten, Stein, Harald, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Küppers, Ralf, Klapper, Wolfram und Siebert, Reiner
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Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.
Blood 118 (1), S. 139-147.
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VerMilyea, Matthew, Maneck, Matthias, Yoshida, Naoko, Blochberger, Isabell, Suzuki, Emi, Suzuki, Toru, Spang, Rainer, Klein, Christoph A. und Perry, Anthony C. F.
(2011)
Transcriptome asymmetry within mouse zygotes but not between early embryonic sister blastomeres.
The EMBO journal 30 (9), S. 1841-1851.
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Seitz, Volkhard, Butzhammer, Peter, Hirsch, Burkhard, Hecht, Jochen, Gütgemann, Ines, Ehlers, Anke, Lenze, Dido, Oker, Elisabeth, Sommerfeld, Anke, von der Wall, Edda, König, Christoph, Zinser, Christian, Spang, Rainer und Hummel, Michael
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Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma.
PLoS One 6 (11), e26837.
Lang, Elmar, Schachtner, R., Lutter, D., Herold, Daniela, Kodewitz, A., Blöchl, F..J., Theis, Fabian J., Keck, Ingo R., Gorriz, J. M., Gomez-Vilda, P. und Tome, A. M.
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I, 2. Exploratory Matrix Factorization Techniques for Large Scale Biomedical Data Sets.
In: Gorriz, Juan Manuel und Lang, Elmar W. und Ramírez, Javier, (eds.)
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Bentham Science Publishers, Hilversum, S. 26-47.
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2010
Scholtysik, René, Kreuz, Markus, Klapper, Wolfram, Burkhardt, Birgit, Feller, Alfred, Hummel, Michael, Loeffler, Markus, Rosolowski, Maciej, Schwaenen, Carsten, Spang, Rainer, Stein, Harald, Thorns, Christoph, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Zenz, Thorsten, Siebert, Reiner und Küppers, Ralf
(2010)
Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis.
Haematologica 95 (12), S. 2047-2055.
Dettmer, Katja, Almstetter, Martin F., Appel, Inka, Nürnberger, Nadine, Schlamberger, Gregor, Gronwald, Wolfram, Meyer, Heinrich H. D. und Oefner, Peter J.
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Comparison of serum versus plasma collection in gas chromatography--mass spectrometry-based metabolomics.
Electrophoresis 31 (14), S. 2365-2373.
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Neusser, Matthias A., Lindenmeyer, Maja T., Moll, Anton G., Segerer, Stephan, Edenhofer, Ilka, Sen, Kontheari, Stiehl, Daniel P., Kretzler, Matthias, Gröne, Hermann-Josef, Schlöndorff, Detlef und Cohen, Clemens D.
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Human nephrosclerosis triggers a hypoxia-related glomerulopathy.
The American journal of pathology 176 (2), S. 594-607.
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Ingersoll, Molly A., Spanbroek, Rainer, Lottaz, Claudio, Gautier, Emmanuel L., Frankenberger, Marion, Hoffmann, Reinhard, Lang, Roland, Haniffa, Muzlifah, Collin, Matthew, Tacke, Frank, Habenicht, Andreas J. R., Ziegler-Heitbrock, Loems und Randolph, Gwendalyn J.
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Comparison of gene expression profiles between human and mouse monocyte subsets.
Blood 115 (3), e10-e19.
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Hundsrucker, Christian, Skroblin, Philipp, Christian, Frank, Zenn, Hans-Michael, Popara, Viola, Joshi, Mangesh, Eichhorst, Jenny, Wiesner, Burkhard, Herberg, Friedrich W., Reif, Bernd, Rosenthal, Walter und Klussmann, Enno
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Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein.
The Journal of biological chemistry 285 (8), S. 5507-5521.
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Lottaz, Claudio, Beier, Dagmar, Meyer, Katharina, Kumar, Praveen, Hermann, Andreas, Schwarz, Johannes, Junker, Markus, Oefner, Peter J., Bogdahn, Ulrich, Wischhusen, J., Spang, Rainer, Storch, Alexander und Beier, Christoph P.
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Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.
Cancer research 70 (5), S. 2030-2040.
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2009
Thieme, Marian, Lottaz, Claudio, Niederstätter, Harald, Parson, Walther, Spang, Rainer und Oefner, Peter J.
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ReseqChip: automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly.
BMC bioinformatics 10, S. 440.
Geue, Lutz, Klare, Sabrina, Schnick, Christina, Mintel, Birgit, Meyer, Katharina und Conraths, Franz J.
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Analysis of the clonal relationship of serotype O26:H11 enterohemorrhagic Escherichia coli isolates from cattle.
Applied and environmental microbiology 75 (21), S. 6947-6953.
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Förster, Frank, Liang, Chunguang, Shkumatov, Alexander V., Beisser, Daniela, Engelmann, Julia C., Schnölzer, Martina, Frohme, Marcus, Müller, Tobias, Schill, Ralph O. und Dandekar, Thomas
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Tardigrade workbench: comparing stress-related proteins, sequence-similar and functional protein clusters as well as RNA elements in tardigrades.
BMC genomics 10, S. 469.
Lee, Chil-Woo, Efetova, Marina, Engelmann, Julia C., Kramell, Robert, Wasternack, Claus, Ludwig-Müller, Jutta, Hedrich, Rainer und Deeken, Rosalia
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Agrobacterium tumefaciens promotes tumor induction by modulating pathogen defense in Arabidopsis thaliana.
The Plant cell 21 (9), S. 2948-2962.
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Lyck, Ruth, Ruderisch, Nadine, Moll, Anton G., Steiner, Oliver, Cohen, Clemens D., Engelhardt, Britta, Makrides, Victoria und Verrey, Francois
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Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 29 (9), S. 1491-1502.
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Allam, Ramanjaneyulu, Lichtnekert, Julia, Moll, Anton G., Taubitz, Anela, Vielhauer, Volker und Anders, Hans-Joachim
(2009)
Viral RNA and DNA trigger common antiviral responses in mesangial cells.
Journal of the American Society of Nephrology : JASN 20 (9), S. 1986-1996.
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Eberhart, K., Renner, Kathrin, Ritter, I., Kastenberger, M., Singer, K., Hellerbrand, Claus, Kreutz, Marina, Kofler, R. und Oefner, Peter J.
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Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis.
Leukemia 23 (11), S. 2167-2170.
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Almstetter, Martin F., Appel, Inka, Gruber, Michael, Lottaz, Claudio, Timischl, Birgit, Spang, Rainer, Dettmer, Katja und Oefner, Peter J.
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Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Analytical chemistry 81 (14), S. 5731-5739.
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Vlad, Marcel O., Corlan, Alexandru D., Morán, Federico, Spang, Rainer, Oefner, Peter J. und Ross, John
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Kinetic laws, phase-phase expansions, renormalization group, and INR calibration.
Proceedings of the National Academy of Sciences of the United States of America 106 (16), S. 6465-6470.
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Anchang, Benedict Nchang, Sadeh, Mohammad Javad, Jacob, Juby, Tresch, Achim, Vlad, Marcel O., Oefner, Peter J. und Spang, Rainer
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Modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models.
Proceedings of the National Academy of Sciences of the United States of America 106 (16), S. 6447-6452.
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Martín-Subero, José I., Kreuz, Markus, Bibikova, Marina, Bentink, Stefan, Ammerpohl, Ole, Wickham-Garcia, Eliza, Rosolowski, Maciej, Richter, Julia, Lopez-Serra, Lidia, Ballestar, Esteban, Berger, Hilmar, Agirre, Xabier, Bernd, Heinz-Wolfram, Calvanese, Vincenzo, Cogliatti, Sergio B., Drexler, Hans G., Fan, Jian-Bing, Fraga, Mario F., Hansmann, Martin L., Hummel, Michael, Klapper, Wolfram, Korn, Bernhard, Küppers, Ralf, Macleod, Roderick A. F., Möller, Peter, Ott, German, Pott, Christiane, Prosper, Felipe, Rosenwald, Andreas, Schwaenen, Carsten, Schübeler, Dirk, Seifert, Marc, Stürzenhofecker, Benjamin, Weber, Michael, Wessendorf, Swen, Loeffler, Markus, Trümper, Lorenz, Stein, Harald, Spang, Rainer, Esteller, Manel, Barker, David, Hasenclever, Dirk und Siebert, Reiner
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New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling.
Blood 113 (11), S. 2488-2497.
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Schwaenen, Carsten, Viardot, Andreas, Berger, Hilmar, Barth, Thomas F. E., Bentink, Stefan, Döhner, Hartmut, Enz, Martina, Feller, Alfred C., Hansmann, Martin-Leo, Hummel, Michael, Kestler, Hans A., Klapper, Wolfram, Kreuz, Markus, Lenze, Dido, Loeffler, Markus, Möller, Peter, Müller-Hermelink, Hans-Konrad, Ott, German, Rosolowski, Maciej, Rosenwald, Andreas, Ruf, Sandra, Siebert, Reiner, Spang, Rainer, Stein, Harald, Truemper, Lorenz, Lichter, Peter, Bentz, Martin und Wessendorf, Swen
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Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status.
Genes, Chromosomes and Cancer 48 (1), S. 39-54.
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Engelmann, Julia C., Rahmann, Sven, Wolf, Matthias, Schultz, Jörg, Fritzilas, Epameinondas, Kneitz, Susanne, Dandekar, Thomas und Müller, Tobias
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Modelling cross-hybridization on phylogenetic DNA microarrays increases the detection power of closely related species.
Molecular ecology resources 9 (1), S. 83-93.
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Moll, Anton G., Lindenmeyer, Maja T., Kretzler, Matthias, Nelson, Peter J., Zimmer, Ralf und Cohen, Clemens D.
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Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays.
PloS ONE 4 (3), e4702.
2008
Fröhlich, H., Beissbarth, T., Tresch, A., Kostka, D., Jacob, Juby, Spang, Rainer und Markowetz, F.
(2008)
Analyzing gene perturbation screens with nested effects models in R and bioconductor.
Bioinformatics 24 (21), S. 2549-2550.
Volltext nicht vorhanden.
Engelmann, Julia C., Deeken, R., Muller, T., Nimtz, G., Roelfsema, M. R. und Hedrich, R.
(2008)
Is gene activity in plant cells affected by UMTS-irradiation? A whole genome approach.
Advances and Applications in Bioinformatics and Chemistry (Adv Appl Bioinform Chem) 1, S. 71-83.
Bentink, Stefan, Wessendorf, S., Schwaenen, C., Rosolowski, M., Klapper, W., Rosenwald, A., Ott, G., Banham, A. H., Berger, H., Feller, A. C., Hansmann, M. L., Hasenclever, D., Hummel, M., Lenze, D., Möller, P., Stuerzenhofecker, B., Loeffler, M., Truemper, L., Stein, H., Siebert, R. und Spang, Rainer
(2008)
Pathway activation patterns in diffuse large B-cell lymphomas.
Leukemia 22 (9), S. 1746-1754.
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Klapper, W., Szczepanowski, M., Burkhardt, B., Berger, H., Rosolowski, M., Bentink, Stefan, Schwaenen, C., Wessendorf, S., Spang, Rainer, Moller, P., Hansmann, M. L., Bernd, H. W., Ott, G., Hummel, M., Stein, H., Loeffler, M., Trumper, L., Zimmermann, M., Reiter, A. und Siebert, R.
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Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials.
Blood 112 (4), S. 1374-1381.
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Cohen, C. D., Lindenmeyer, M. T., Eichinger, F., Hahn, A., Seifert, M., Moll, Anton G., Schmid, H., Kiss, E., Grone, E., Grone, H. J., Kretzler, M., Werner, T. und Nelson, P. J.
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Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis.
PLoS ONE 3 (8), e2937.
Dohm, Juliane C., Lottaz, Claudio, Borodina, Tatiana und Himmelbauer, Heinz
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Substantial biases in ultra-short read data sets from high-throughput DNA sequencing.
Nucleic Acids Research 36 (16), e105.
Dierlamm, J., Murga Penas, E. M., Bentink, Stefan, Wessendorf, S., Berger, H., Hummel, M., Klapper, W., Lenze, D., Rosenwald, A., Haralambieva, E., Ott, G., Cogliatti, S. B., Möller, Peter, Schwaenen, C., Stein, H., Löffler, M., Spang, Rainer, Trumper, L. und Siebert, Reiner
(2008)
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.
Haematologica 93 (5), S. 688-696.
Jacob, Juby, Jentsch, M., Kostka, Dennis, Bentink, Stefan und Spang, Rainer
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Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs.
Bioinformatics 24 (7), S. 995-1001.
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Blenk, Steffen, Engelmann, Julia C., Pinkert, Stefan, Weniger, Markus, Schultz, Jörg, Rosenwald, Andreas, Müller-Hermelink, Hans K., Müller, Tobias und Dandekar, Thomas
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Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis.
BMC cancer 8, S. 106.
Lottaz, Claudio, Kostka, Dennis und Spang, Rainer
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26. Classification of Patients.
In: Lengauer, Thomas, (ed.)
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Montesinos-Rongen, M., Brunn, A., Bentink, Stefan, Basso, K., Lim, W. K., Klapper, Wolfram, Schaller, C., Reifenberger, G., Rubenstein, J., Wiestler, O. D., Spang, Rainer, Dalla-Favera, R., Siebert, Reiner und Deckert, M.
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Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell.
Leukemia 22 (2), S. 400-405.
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Kostka, Dennis und Spang, Rainer
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Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures.
PLoS Computational Biology 4 (2), e22.
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Humana Press, Totowa, NJ, S. 281-296.
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2007
Blenk, S., Engelmann, Julia C., Weniger, M., Schultz, J., Dittrich, M., Rosenwald, A., Müller-Hermelink, H. K., Müller, T. und Dandekar, T.
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Germinal center B cell-like (GCB) and activated B cell-like (ABC) type of diffuse large B cell lymphoma (DLBCL): analysis of molecular predictors, signatures, cell cycle state and patient survival.
Cancer Informatics 3, S. 399-420.
Roesch, Alexander, Becker, Bernd, Bentink, Stefan, Spang, Rainer, Vogl, Annegret, Hagen, Ilja, Landthaler, Michael und Vogt, Thomas
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Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Prevention 16 (11), S. 2486-2490.
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Hoffmann, Reinhard, Lottaz, Claudio, Kühne, Thomas, Rolink, Antonius und Melchers, Fritz
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Neutrality, compensation, and negative selection during evolution of B-cell development transcriptomes.
Molecular Biology and Evolution (Mol Biol Evol) 24 (12), S. 2610-2618.
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Lottaz, Claudio, Toedling, Joern und Spang, Rainer
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Annotation-based distance measures for patient subgroup discovery in clinical microarray studies.
Bioinformatics 23 (17), S. 2256-2264.
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Markowetz, Florian und Spang, Rainer
(2007)
Inferring cellular networks - a review.
BMC bioinformatics 8 Suppl 6, S5.
Dohm, Juliane C., Lottaz, Claudio, Borodina, Tatiana und Himmelbauer, Heinz
(2007)
SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing.
Genome Research 17 (11), S. 1697-1706.
Volltext nicht vorhanden.
Bullinger, Lars, Rücker, Frank G., Kurz, Stephan, Du, Juan, Scholl, Claudia, Sander, Sandrine, Corbacioglu, Andrea, Lottaz, Claudio, Krauter, Jürgen, Fröhling, Stefan, Ganser, Arnold, Schlenk, Richard F., Döhner, Konstanze, Pollack, Jonathan R. und Döhner, Hartmut
(2007)
Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia.
Blood 110 (4), S. 1291-1300.
Volltext nicht vorhanden.
Weniger, M., Engelmann, Julia C. und Schultz, J.
(2007)
Genome Expression Pathway Analysis Tool--analysis and visualization of microarray gene expression data under genomic, proteomic and metabolic context.
BMC Bioinformatics 8, S. 179.
Rhein, P., Scheid, S., Ratei, R., Hagemeier, C., Seeger, K., Kirschner-Schwabe, R., Moericke, A., Schrappe, M., Spang, Rainer, Ludwig, W.-D. und Karawajew, L.
(2007)
Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.
Leukemia 21 (5), S. 897-905.
Volltext nicht vorhanden.
Jaeger, Jochen, Koczan, Dirk, Thiesen, Hans-Juergen, Ibrahim, Saleh M., Gross, Gerd, Spang, Rainer und Kunz, Manfred
(2007)
Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues.
Clinical cancer research 13 (3), S. 806-815.
Volltext nicht vorhanden.
2006
Jaeger, J. und Spang, Rainer
(2006)
Selecting normalization genes for small diagnostic microarrays.
BMC Bioinformatics 7, S. 388.
Kirschner-Schwabe, R., Lottaz, Claudio, Todling, J., Rhein, P., Karawajew, L., Eckert, C., von Stackelberg, A., Ungethum, U., Kostka, Dennis, Kulozik, A. E., Ludwig, W. D., Henze, G., Spang, Rainer, Hagemeier, C. und Seeger, K.
(2006)
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia.
Clinical Cancer Research 12 (15), S. 4553-4561.
Volltext nicht vorhanden.
Lottaz, Claudio, Yang, Xinan, Scheid, Stefanie und Spang, Rainer
(2006)
OrderedList - a bioconductor package for detecting similarity in ordered gene lists.
Bioinformatics 22 (18), S. 2315-2316.
Volltext nicht vorhanden.
Hummel, M., Bentink, S., Berger, H., Klapper, W., Wessendorf, S., Barth, T. F., Bernd, H. W., Cogliatti, S. B., Dierlamm, J., Feller, A. C. und Spang, Rainer
(2006)
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.
New England Journal of Medicine 354 (23), S. 2419-2430.
Volltext nicht vorhanden.
Toedling, J., Rhein, P., Ratei, R., Karawajew, L. und Spang, Rainer
(2006)
Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring.
BMC Bioinformatics 7, S. 282.
2005
Markowetz, F., Bloch, J. und Spang, Rainer
(2005)
Non-transcriptional pathway features reconstructed from secondary effects of RNA interference.
Bioinformatics 21 (21), S. 4026-4032.
Volltext nicht vorhanden.
Yang, X., Bentink, Stefan und Spang, Rainer
(2005)
Detecting common gene expression patterns in multiple cancer outcome entities.
Biomedical Microdevices 7 (3), S. 247-251.
Volltext nicht vorhanden.
Lottaz, Claudio und Spang, Rainer
(2005)
stam – a Bioconductor compliant R package for structured analysis of microarray data.
BMC Bioinformatics 6, S. 211.
Scheid, S. und Spang, Rainer
(2005)
twilight; a Bioconductor package for estimating the local false discovery rate.
Bioinformatics 21 (12), S. 2921-2922.
Volltext nicht vorhanden.
Jaeger, J., Weichenhan, D., Ivandic, B. und Spang, Rainer
(2005)
Early diagnostic marker panel determination for microarray based clinical studies.
Statistical Applications in Genetics and Molecular Biology 4 (1), article 9.
Volltext nicht vorhanden.
Lottaz, Claudio und Spang, Rainer
(2005)
Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data.
Bioinformatics 21 (9), S. 1971-1978.
Lottaz, Claudio, Kostka, Dennis, Markowetz, Florian und Spang, Rainer
(2005)
Traces of molecular disease mechanisms on microarrays.
Methods in Molecular Biology 453, S. 281-296.
Volltext nicht vorhanden.
2004
Kostka, Dennis und Spang, Rainer
(2004)
Finding disease specific alterations in the co-expression of genes.
Bioinformatics 20 Suppl 1, i194-i199.
Volltext nicht vorhanden.
Scheid, Stefanie und Spang, Rainer
(2004)
A stochastic downhill search algorithm for estimating the local false discovery rate.
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB 1 (3), S. 98-108.
Volltext nicht vorhanden.
2003
Blaxall, B. C., Spang, Rainer, Rockman, H. A. und Koch, W. J.
(2003)
Differential myocardial gene expression in the development and rescue of murine heart failure.
Physiological Genomics 15 (2), S. 105-114.
Volltext nicht vorhanden.
Lottaz, Claudio, Iseli, Christian, Jongeneel, C. Victor und Bucher, Philipp
(2003)
Modeling sequencing errors by combining Hidden Markov models.
Bioinformatics 19 (Suppl2), ii103-ii112.
Grzeskowiak, R., Witt, Henning, Drungowski, M., Thermann, R., Hennig, S., Perrot, A., Osterziel, K., Klingbiel, D., Scheid, Stefanie und Spang, Rainer
(2003)
Expression profiling of human idiopathic dilated cardiomyopathy.
Cardiovascular Research 59, S. 400-411.
Volltext nicht vorhanden.
2002
Muller, Tobias, Spang, Rainer und Vingron, M.
(2002)
Estimating amino acid substitution models: a comparison of Dayhoff's estimator, the resolvent approach and a maximum likelihood method.
Molecular Biology and Evolution 19 (1), S. 8-13.
Volltext nicht vorhanden.
Spang, Rainer, Rehmsmeier, M. und Stoye, J.
(2002)
A novel approach to remote homology detection: jumping alignments.
Journal of Computational Biology 9 (5), S. 747-760.
Volltext nicht vorhanden.
Spang, Rainer, Zuzan, H., West, M., Nevins, J., Blanchette, C. und Marks, J. R.
(2002)
Prediction and uncertainty in the analysis of gene expression profiles.
In Silico Biology 2 (3), S. 369-381.
Volltext nicht vorhanden.
2001
West, M., Blanchette, C., Dressman, H., Huang, E., Ishida, S., Spang, Rainer, Zuzan, H., Olson, J. A., Marks, J. R. und Nevins, J. R.
(2001)
Predicting the clinical status of human breast cancer by using gene expression profiles.
Proc. Natl. Acad. Sci. U.S.A. 98 (20), S. 11462-11467.
Volltext nicht vorhanden.
Ishida, S., Huang, E., Zuzan, H., Spang, Rainer, Leone, G., West, M. und Nevins, J. R.
(2001)
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.
Mol. Cell. Biol. 21 (14), S. 4684-4699.
Volltext nicht vorhanden.
Spang, Rainer und Vingron, M.
(2001)
Limits of homology detection by pairwise sequence comparison.
Bioinformatics 17 (4), S. 338-342.
Volltext nicht vorhanden.
2000
Lottaz, Claudio, Stouffs, Rudi und Smith, Ian
(2000)
Increasing Understanding During Collaboration Through Advanced Representations.
ITcon : Journal of information technology in construction 5, S. 1-24.
Spang, Rainer, Rehmsmeier, M. und Stoye, J.
(2000)
Sequence database search using jumping alignments.
Proc Int Conf Intell Syst Mol Biol 8, S. 367-375.
Volltext nicht vorhanden.
1999
Lottaz, Claudio, Clément, Denis, Faltings, Boi und Smith, I. F. C.
(1999)
Constraint-Based Support for Collaboration in Design and Construction.
Journal of Computing in Civil Engineering 13 (1), S. 23-35.
Volltext nicht vorhanden.
Lottaz, Claudio
(1999)
Rewriting numeric constraint satisfaction problems for consistency algorithms (short paper).
In: Jaffar, Joxan, (ed.)
Principles and Practice of Constraint Programming – CP’99.
Lecture Notes in Computer Science, 1713.
Springer, Berlin, S. 486-487.
ISBN 978-3-540-48085-3 (online). 978-3-540-66626-4 (print).
Volltext nicht vorhanden.
1998
Lottaz, Claudio, Sam-Haroud, D., Faltings, B. und Smith, I.
(1998)
Constraint techniques for collaborative design.
In:
Proceedings Tenth IEEE International Conference on Tools with Artificial Intelligence (Cat. No.98CH36294).
IEEE Computer Soc., Los Alamitos, Calif., S. 34-41.
ISBN 0-7803-5214-9.
Volltext nicht vorhanden.
Lottaz, Claudio, Stalker, Ruth und Smith, Ian
(1998)
Constraint solving and preference activation for interactive design.
AI EDAM - Artificial Intelligence for Engineering Design, Analysis and Manufacturing 12, S. 12-13.
Volltext nicht vorhanden.
Spang, Rainer und Vingron, M.
(1998)
Statistics of large-scale sequence searching.
Bioinformatics 14 (3), S. 279-284.
Volltext nicht vorhanden.
1996
Lottaz, Claudio
(1996)
Constraint Solving, Preference Activation and Solution Adaptation in IDIOM.
Swiss Federal Institute of Technology (EPFL), Lausanne, Schweiz.
Volltext nicht vorhanden.
Smith, Ian, Stalker, Ruth und Lottaz, Claudio
(1996)
Creating Design Objects from Cases for Interactive Spatial Composition.
In: Gero, J. S. und Sudweeks, F., (eds.)
Artificial Intelligence in Design ’96 (Boston MA, USA).
Springer, Dordrecht, S. 97-116.
ISBN 978-94-009-0279-4 (online), 978-94-010-6610-5 (Print).
Volltext nicht vorhanden.
1995
Smith, Ian, Lottaz, Claudio und Faltings, Boi
(1995)
Spatial composition using cases: IDIOM.
In: Veloso, M. und Aamodt, A., (eds.)
Case-Based Reasoning Research and Development. ICCBR 1995.
Lecture Notes in Computer Science (Lecture Notes in Artificial Intelligence), 1010.
Springer, Berlin, S. 88-97.
ISBN 978-3-540-48446-2 (online), 978-3-540-60598-0 (print).
Volltext nicht vorhanden.
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