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Anzahl der Einträge in dieser Kategorie: 147.

2018

Reinke, Sarah , Richter, Julia, Fend, Falko, Feller, Alfred, Hansmann, Martin-Leo, Hüttl, Katrin, Oschlies, Ilske, Ott, German, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Altenbuchinger, Michael, Spang, Rainer und Klapper, Wolfram (2018) Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma—a feasibility study using full slide staining. Virchows Archiv. Volltext nicht vorhanden.

Görtler, Franziska, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J. , Spang, Rainer und Altenbuchinger, Michael (2018) Loss-function learning for digital tissue deconvolution. In: Raphael, Benjamin J., (ed.) Research in Computational Molecular Biology : 22nd Annual International Conference, RECOMB 2018, Paris, France, April 21-24, 2018, Proceedings. Lecture Notes in Computer Science, 10812. Springer International Publishing, Cham, S. 75-89. ISBN 978-3-319-89929-9 ; 978-3-319-89928-2. Volltext nicht vorhanden.

Feist, M., Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, J., von Bonin, F., Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja , Gronwald, Wolfram , Reinders, Jörg , Engelmann, Julia C. , Dudek, J., Klapper, W., Trumper, L., Spang, Rainer, Oefner, Peter J. und Kube, D. (2018) Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression. Nat Commun 9 (1), S. 1514.

Horn, H., Kohler, Christian, Witzig, R., Kreuz, M., Leich, E., Klapper, W., Hummel, M., Loeffler, M., Trumper, L., Spang, Rainer, Rosenwald, A. und Ott, G. (2018) Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2. Haematologica. Volltext nicht vorhanden.

Moll, Anton G. (2018) Semi-supervised Classification of Breast Cancer Expression Profiles Using Neural Networks. Dissertation, Universität Regensburg.

2017

Paul, U., Richter, J., Stuhlmann-Laiesz, C., Kreuz, M., Nagel, I., Horn, H., Staiger, A. M., Aukema, S. M., Hummel, M., Ott, G., Spang, Rainer, Rosenwald, A., Feller, A. C., Cogliatti, S., Stein, H., Hansmann, M. L., Moller, P., Szczepanowski, M., Burkhardt, B., Pfreundschuh, M., Schmitz, N., Loeffler, M., Trumper, L., Siebert, R. und Klapper, W. (2017) Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC. Leuk. Lymphoma, S. 1-9. Volltext nicht vorhanden.

Zacharias, Helena, Rehberg, Thorsten, Mehrl, S., Richtmann, D., Wettig, Tilo, Oefner, Peter J. , Spang, Rainer, Gronwald, Wolfram und Altenbuchinger, Michael (2017) Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints. J. Proteome Res.. Volltext nicht vorhanden.

Chen, J., Strieder, Nicholas, Krohn, N.G., Cyprys, P., Sprunck, S., Engelmann, Julia C. und Dresselhaus, Thomas (2017) Zygotic Genome Activation Occurs Shortly After Fertilization in Maize. Plant Cell.

Cascione, L., Rinaldi, A., Chiappella, A., Kwee, I., Ciccone, G., Altenbuchinger, Michael, Kohler, Christian , Vitolo, U., Inghirami, G. und Bertoni, F. (2017) Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study. Br J Haematol. Volltext nicht vorhanden.

Altenbuchinger, Michael, Schwarzfischer, Philipp, Rehberg, Thorsten, Reinders, Jörg , Kohler, Christian , Gronwald, Wolfram , Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, Peter J. und Spang, Rainer (2017) Molecular signatures that can be transferred across different omics platforms. Bioinformatics 33 (14), i333-i340. Volltext nicht vorhanden.

Oschlies, I., Kohler, Christian, Szczepanowski, Monika, Koch, K., Gontarewicz, A., Metze, D., Hillen, U., Richter, J., Spang, Rainer und Klapper, W. (2017) Spindle-cell variant of primary cutaneous follicle center B-cell lymphomas are germinal center B-cell lymphomas by gene expression profiling using formalin-fixed paraffin embedded specimen. J Invest Dermatol. Volltext nicht vorhanden.

Szczepanowski, M., Lange, J., Kohler, Christian, Masque-Soler, N., Zimmermann, M., Aukema, S. M., Altenbuchinger, Michael, Rehberg, Thorsten, Mahn, F., Siebert, R., Spang, Rainer, Burkhardt, B. und Klapper, W. (2017) Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents. Br. J. Haematol.. Volltext nicht vorhanden.

Rohde, M., Bonn, B. R., Zimmermann, M., Lange, J., Moricke, A., Klapper, W., Oschlies, I., Szczepanowski, M., Nagel, I., Schrappe, M., Loeffler, M., Siebert, R., Reiter, A., Burkhardt, B., Altenbuchinger, Michael, Dettmer-Wilde, Katja, Engelmann, Julia C. , Gronwald, Wolfram , Oefner, Peter J. , Schwarzfischer, Philipp, Taruttis, Franziska und Spang, Rainer (2017) Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols. Haematologica 102 (6), S. 1091-1098. Volltext nicht vorhanden.

Feist, M., Kemper, J., Taruttis, Franziska, Rehberg, Thorsten, Engelmann, Julia C., Gronwald, Wolfram, Hummel, Michael, Spang, Rainer und Kube, Dieter (2017) Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis. International Journal of Cancer: Int. J. Cancer. Volltext nicht vorhanden.

Maliniemi, P., Laukkanen, K., Vakeva, L., Dettmer, Katja , Lipsanen, T., Jeskanen, L., Bessede, A., Oefner, Peter J. , Kadin, M. E. und Ranki, A. (2017) Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas. Oncoimmunology 6 (3), e1273310. Volltext nicht vorhanden.

Schwarzfischer, Philipp, Reinders, Jörg , Dettmer, Katja , Kleo, K., Dimitrova, L., Hummel, M., Feist, M., Kube, D., Szczepanowski, M., Klapper, W., Taruttis, Franziska, Engelmann, Julia C. , Spang, Rainer, Gronwald, Wolfram und Oefner, Peter J. (2017) Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism. Journal of Proteome Research 16, S. 1105-1120. Volltext nicht vorhanden.

Taruttis, Franziska, Feist, M., Schwarzfischer, Philipp, Gronwald, Wolfram , Kube, D., Spang, Rainer und Engelmann, Julia C. (2017) External calibration with Drosophila whole-cell spike-ins delivers absolute mRNA fold changes from human RNA-Seq and qPCR data. BioTechniques 62 (2), S. 53-61. Volltext nicht vorhanden.

Lottaz, Claudio, Gronwald, Wolfram , Spang, Rainer und Engelmann, Julia C. (2017) High-Dimensional Profiling for Computational Diagnosis. In: Bioinformatics : Volume II: Structure, Function, and Applications. Methods in Molecular Biology, 1526. Springer, New York, S. 205-229. ISBN 978-1-4939-6611-0. Volltext nicht vorhanden.

2016

Hosseini, H., Obradovic, M. M., Hoffmann, M., Harper, K. L., Sosa, M. S., Werner-Klein, M., Nanduri, L. K., Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, Michael, Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., Fehm, T., Rack, B., Buchholz, S., Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, J. A. und Klein, Christoph A. (2016) Early dissemination seeds metastasis in breast cancer. Nature 540, S. 552-558. Volltext nicht vorhanden.

Dueck, A., Evers, M., Henz, S. R., Unger, K., Eichner, N., Merkl, Rainer , Berezikov, E., Engelmann, Julia C., Weigel, D., Wenzl, S. und Meister, Gunter (2016) Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants. BMC Genomics 17 (1), S. 853.

Altenbuchinger, Michael, Rehberg, Thorsten, Zacharias, Helena, Stämmler, Frank, Dettmer, Katja , Weber, Daniela, Hiergeist, Andreas, Gessner, Andre , Holler, Ernst, Oefner, Peter J. und Spang, Rainer (2016) Reference point insensitive molecular data analysis. Bioinformatics.

Coll-Bonfill, N., Peinado, V. I., Pisano, M. V., Parrizas, M., Blanco, I., Evers, Maurits, Engelmann, Julia C., Garcia-Lucio, J., Tura-Ceide, O., Meister, Gunter, Barbera, J. A. und Musri, M. M. (2016) Slug Is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype. PLoS ONE 11 (7), e0159460.

Pirkl, Martin Franz-Xaver (2016) Indirect inference of synergistic and alternative signalling of intracellular pathways. Dissertation, Universität Regensburg.

Stämmler, Frank, Gläsner, Joachim, Hiergeist, Andreas, Holler, Ernst, Weber, Daniela, Oefner, Peter J., Gessner, Andre und Spang, Rainer (2016) Adjusting microbiome profiles for differences in microbial load by spike-in bacteria. Microbiome 4 (1), S. 28.

Stämmler, Frank, Glasner, J., Hiergeist, Andreas , Holler, Ernst, Weber, Daniela, Oefner, Peter J. , Gessner, Andre und Spang, Rainer (2016) Adjusting microbiome profiles for differences in microbial load by spike-in bacteria. Microbiome 4 (1), S. 28.

Moffa, Giusi, Erdmann, Gerrit, Voloshanenko, Oksana, Hundsrucker, Christian, Sadeh, Mohammad Javad, Boutros, Michael und Spang, Rainer (2016) Refining Pathways: A Model Comparison Approach. PLoS One 11 (6), e0155999.

Teufel, Andreas, Itzel, Timo, Erhart, W., Brosch, M., Wang, X. Y., Kim, Y. O., von Schonfels, W., Herrmann, A., Bruckner, S., Stickel, F., Dufour, J. F., Chavakis, T., Hellerbrand, Claus, Spang, Rainer, Maass, Thorsten, Becker, T., Schreiber, S., Schafmayer, C., Schuppan, D. und Hampe, J. (2016) Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues from Patients. Gastroenterology. Volltext nicht vorhanden.

Schrader, A., Meyer, Katharina, Walther, N., Stolz, A., Feist, M., Hand, E., Bonin, F. von, Evers, Maurits, Kohler, Christian, Shirneshan, K., Vockerodt, M., Klapper, W., Szczepanowski, M., Murray, P. G., Bastians, H., Trümper, Lorenz, Spang, Rainer und Kube, Dieter (2016) Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data. OncoTarget.

Weber, Daniela, Oefner, Peter J., Dettmer, Katja, Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Stämmler, Frank, Hahn, Joachim, Wolff, Daniel, Herr, Wolfgang und Holler, Ernst (2016) Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation. Bone Marrow Transplant.. Volltext nicht vorhanden.

Moeckel, Sylvia, Vollmann-Zwerenz, Arabel, Proescholdt, Martin A., Brawanski, Alexander, Riemenschneider, Markus J., Bogdahn, Ulrich, Bosserhoff, A. K., Spang, Rainer und Hau, Peter (2016) Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro. PLoS ONE 11 (3), e0151312.

Voelxen, N. F., Walenta, S., Proescholdt, Martin A., Dettmer, Katja, Pusch, S. und Mueller-Klieser, W. (2016) Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique. Frontiers in Oncology 6, S. 46.

2015

Loedige, Inga, Jakob, Leonhard, Treiber, Thomas, Ray, Debashish, Stotz, Mathias, Treiber, Nora, Hennig, Janosch, Cook, Kate B., Morris, Quaid, Hughes, Timothy R., Engelmann, Julia C., Krahn, Michael P. und Meister, Gunter (2015) The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation. Cell Rep (Cell Reports) 13 (6), S. 1206-1220.

Evers, Maurits, Huttner, Michael, Dueck, Anne, Meister, Gunter und Engelmann, Julia C. (2015) miRA: adaptable novel miRNA identification in plants using small RNA sequencing data. BMC Bioinformatics 16 (370), S. 1-10.

Pirkl, Martin, Hand, E., Kube, D. und Spang, Rainer (2015) Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models. Bioinformatics.

Hochrein, Jochen, Zacharias, Helena, Taruttis, Franziska, Samol, Claudia, Engelmann, Julia C., Spang, Rainer, Oefner, Peter J. und Gronwald, Wolfram (2015) Data Normalization of (1)H NMR Metabolite Fingerprinting Data Sets in the Presence of Unbalanced Metabolite Regulation. J. Proteome Res. 14 (8), S. 3217-3228. Volltext nicht vorhanden.

Taruttis, Franziska, Spang, Rainer und Engelmann, Julia C. (2015) A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA). Bioinformatics 31, S. 22.

Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian W., Aukema, Sietse M., Nagel, Inga, Richter, Julia, Siebert, Reiner, Spang, Rainer, Burkhardt, Birgit und Klapper, Wolfram (2015) Clinical and pathological features of Burkitt lymphoma showing expression of BCL2 - an analysis including gene expression in formalin-fixed paraffin-embedded tissue. British Journal of Haematology = Br J Haematol 171, S. 501-508.

Engelmann, Julia C., Amann, Thomas, Ott-Rötzer, Brigitta, Nützel, Magit, Reinders, Yvonne, Reinders, Jörg, Thasler, Wolfgang E., Kristl, Theresa, Teufel, Andreas, Huber, Christian G., Oefner, Peter J., Spang, Rainer und Hellerbrand, Claus (2015) Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma. PLoS Computational Biology 11 (5), S. 1-22.

Weber, Daniela, Oefner, Peter J., Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja und Holler, Ernst (2015) Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome. Blood 126 (14), S. 1723-1728.

2014

Hau, Peter, Moeckel, Sylvia, Meyer, Katharina, Leukel, Petra, Heudorfer, Fabian, Seliger, Corinna, Stangl, Christina, Bogdahn, Ulrich, Proescholdt, Martin A., Brawanski, Alexander, Vollmann-Zwerenz, Arabel, Riemenschneider, Markus J., Bosserhoff, Anja-Katrin und Spang, Rainer (2014) Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro. PLoS ONE 9 (9), e108632.

Winkler, Thomas W., Kutalik, Zoltan, Gorski, Mathias, Lottaz, Claudio, Kronenberg, Florian und Heid, Iris M. (2014) EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data. Bioinformatics, btu621. Volltext nicht vorhanden.

Vossenkämper, Anna, Hundsrucker, Christian, Page, Kevin, van Maurik, Andre, Sanders, Theodore J., Stagg, Andrew J., Das, Lisa und MacDonald, Thomas T. (2014) A CD3-Specific Antibody Reduces Cytokine Production and Alters Phosphoprotein Profiles in Intestinal Tissues From Patients With Inflammatory Bowel Disease. The American Journal of Gastroenterology 147 (1), S. 172-183. Volltext nicht vorhanden.

Hannus, Michael, Beitzinger, Michaela, Engelmann, Julia C., Weickert, Marie-Theresa, Spang, Rainer, Hannus, Stefan und Meister, Gunter (2014) siPools: highly complex but accurately defined siRNA pools eliminate off-target effects. Nucleic Acids Research 42, S. 8049-8061.

Holler, Ernst, Butzhammer, Peter, Schmid, Karin, Hundsrucker, Christian, Koestler, Josef, Peter, Katrin, Zhu, Wentao, Sporrer, Daniela, Hehlgans, Thomas, Kreutz, Marina, Holler, Barbara, Wolff, Daniel, Edinger, Matthias, Andreesen, Reinhard, Levine, John E., Ferrara, James L, Gessner, Andre, Spang, Rainer und Oefner, Peter J. (2014) Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD. Biology of Blood and Marrow Transplantation 20 (5), S. 640-645. Volltext nicht vorhanden.

del Jel, Miriam M., Engelmann, Julia, Kunz, Manfred, Schiffner, Susanne, Kuphal, Silke und Bosserhoff, Anja (2014) Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations. Pigment Cell & Melanoma Research 27, S. 678-680. Volltext nicht vorhanden.

Dorn, Christoph, Engelmann, Julia C., Saugspier, Michael Sebastian, Koch, Andreas, Hartmann, Arndt, Spang, Rainer, Bosserhoff, Anja Katrin und Hellerbrand, Claus (2014) Increased expression of c-Jun in nonalcoholic fatty liver disease. Laboratory Investigation 94, S. 394-408. Volltext nicht vorhanden.

Dümcke, Sebastian, Bräuer, Johannes, Anchang, Benedict Nchang, Spang, Rainer, Beerenwinkel, Niko und Tresch, Achim (2014) Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction. Bioinformatics 30 (3), S. 414-419.

Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian, Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, H. G., Hummel, Michael, Jaffe, Elaine S., Kueppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Loeffler, Markus, Mcleod, Roderick A., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, Rene, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Truemper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram und Siebert, Rainer (2014) A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. Blood 123, S. 1187-1198. Volltext nicht vorhanden.

Kuipers, Jack, Moffa, Giusi und Heckerman, David (2014) Addendum on the scoring of Gaussian directed acyclic graphical models. Annals of Statistics. (Im Druck) Volltext nicht vorhanden.

Moffa, Giusi und Kuipers, Jack (2014) Sequential Monte Carlo EM for multivariate probit models. Comp. Stats. & Data An. 72, S. 252-272. Volltext nicht vorhanden.

2013

Schmid, Rainer, Meyer, Katharina, Spang, Rainer, Schittek, Birgit und Bosserhoff, Anja-Katrin (2013) YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis. PLoS ONE 8 (12).

Sadeh, Mohammad Javad, Moffa, Giusi und Spang, Rainer (2013) Considering unknown unknowns: reconstruction of nonconfoundable causal relations in biological networks. Journal of computational biology 20 (11), S. 920-932. Volltext nicht vorhanden.

Voloshanenko, Oksana, Erdmann, Gerrit, Dubash, Taronish D, Augustin, Iris, Metzig, Marie, Moffa, Giusi, Hundsrucker, Christian, Kerr, Grainne, Sandmann, Thomas, Anchang, Benedikt, Demir, Kubilay, Boehm, Christina, Leible, Svenja, Ball, Claudia R, Glimm, Hanno, Spang, Rainer und Boutros, Michael (2013) Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells. Nature communications 4, S. 2610.

Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian, Spang, Rainer und Klapper, Wolfram (2013) Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens. Blood 122 (11), S. 1985-1986.

Schmid, Rainer, Meyer, Katharina, Spang, Rainer, Schittek, Birgit und Bosserhoff, Anja-Katrin (2013) Melanoma inhibitory activity promotes melanoma development through activation of YBX1. Pigment cell & melanoma research 26 (5), S. 685-696. Volltext nicht vorhanden.

Sadeh, Mohammad Javad (2013) Considering unknown unknown: reconstruction of non-confoundable causal relations in biological networks. Dissertation, Universität Regensburg.

Meyer, Katharina (2013) Dissolving heterogeneity in cancer. Dissertation, Universität Regensburg.

Walther, Neele, Ulrich, Antje, Vockerodt, Martina, von Bonin, Frederike, Klapper, Wolfram, Meyer, Katharina, Eberth, Sonja, Pukrop, Tobias, Spang, Rainer, Trümper, Lorenz und Kube, Dieter (2013) Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma. The American journal of pathology 182 (4), S. 1092-1098. Volltext nicht vorhanden.

Kelly, Gemma L, Stylianou, Julianna, Rasaiyaah, Jane, Wei, Wenbin, Thomas, Wendy, Croom-Carter, Deborah, Kohler, Christian, Spang, Rainer, Woodman, Ciaran, Kellam, Paul, Rickinson, Alan N. und Bell, Andrew I. (2013) Different patterns of Epstein-Barr virus latency in endemic Burkitt lymphoma (BL) lead to distinct variants within the BL-associated gene expression signature. Journal of virology 87 (5), S. 2882-2894.

Krentz, S., Hof, J., Mendioroz, A., Vaggopoulou, R., Dörge, P., Lottaz, Claudio, Engelmann, Julia, Groeneveld, T. W. L., Körner, G., Seeger, K., Hagemeier, C., Henze, G., Eckert, C., Stackelberg, A. von und Kirschner-Schwabe, R. (2013) Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia. Leukemia 27 (2), S. 295-304. Volltext nicht vorhanden.

Aryee, Martin J, Liu, Wennuan, Engelmann, Julia C., Nuhn, Philipp, Gurel, Meltem, Haffner, Michael C, Esopi, David, Irizarry, Rafael A, Getzenberg, Robert H, Nelson, William G, Luo, Jun, Xu, Jianfeng, Isaacs, William B, Bova, G Steven und Yegnasubramanian, Srinivasan (2013) DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Science translational medicine 5 (169), 169ra10.

Aukema, Sietse M, Kreuz, Markus, Kohler, Christian, Rosolowski, Maciej, Hasenclever, Dirk, Hummel, Michael, Küppers, Ralf, Lenze, Dido, Ott, German, Pott, Christiane, Richter, Julia, Rosenwald, Andreas, Szczepanowski, Monika, Schwaenen, Carsten, Stein, Harald, Trautmann, Heiko, Wessendorf, Swen, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer, Kluin, Philip M, Klapper, Wolfram und Siebert, Reiner (2013) Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma. Haematologica 99 (4), S. 726-735.

Schif, Birgit, Lennerz, Jochen K., Kohler, Christian, Bentink, Stefan, Kreuz, Markus, Melzner, Ingo, Ritz, Olga, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer und Möller, Peter (2013) SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients. Oncotarget 4 (1), S. 35-47.

Seliger, Corinna, Leukel, Petra, Moeckel, Sylvia, Jachnik, Birgit, Lottaz, Claudio, Kreutz, Marina, Brawanski, Alexander, Proescholdt, Martin, Bogdahn, Ulrich, Bosserhoff, Anja-Katrin, Vollmann-Zwerenz, Arabel und Hau, Peter (2013) Lactate-Modulated Induction of THBS-1 Activates Transforming Growth Factor (TGF)-beta2 and Migration of Glioma Cells In Vitro. PloS one 8 (11), e78935.

Kuipers, Jack und Moffa, Giusi (2013) Uniform random generation of large acyclic digraphs. Stats. & Comp.. Volltext nicht vorhanden.

2012

Hochrein, Jochen, Klein, Matthias S., Zacharias, Helena, Li, Juan, Wijffels, Gene, Schirra, Horst Joachim, Spang, Rainer, Oefner, Peter J. und Gronwald, Wolfram (2012) Performance evaluation of algorithms for the classification of metabolic 1H NMR fingerprints. Journal of proteome research 11 (12), S. 6242-6251. Volltext nicht vorhanden.

Richter, Julia, Schlesner, Matthias, Hoffmann, Steve, Kreuz, Markus, Leich, Ellen, Burkhardt, Birgit, Rosolowski, Maciej, Ammerpohl, Ole, Wagener, Rabea, Bernhart, Stephan H., Lenze, Dido, Szczepanowski, Monika, Paulsen, Maren, Lipinski, Simone, Russell, Robert B., Adam-Klages, Sabine, Apic, Gordana, Claviez, Alexander, Hasenclever, Dirk, Hovestadt, Volker, Hornig, Nadine, Korbel, Jan O, Kube, Dieter, Langenberger, David, Lawerenz, Chris, Lisfeld, Jasmin, Meyer, Katharina, Picelli, Simone, Pischimarov, Jordan, Radlwimmer, Bernhard, Rausch, Tobias, Rohde, Marius, Schilhabel, Markus, Scholtysik, René, Spang, Rainer, Trautmann, Heiko, Zenz, Thorsten, Borkhardt, Arndt, Drexler, Hans G., Möller, Peter, MacLeod, Roderick A. F., Pott, Christiane, Schreiber, Stefan, Trümper, Lorenz, Loeffler, Markus, Stadler, Peter F., Lichter, Peter, Eils, Roland, Küppers, Ralf, Hummel, Michael, Klapper, Wolfram, Rosenstiel, Philip, Rosenwald, Andreas, Brors, Benedikt und Siebert, Reiner (2012) Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nature genetics 44 (12), S. 1316-1320. Volltext nicht vorhanden.

Dolnik, Anna, Engelmann, Julia C., Scharfenberger-Schmeer, Maren, Mauch, Julian, Kelkenberg-Schade, Sabine, Haldemann, Berit, Fries, Tamara, Krönke, Jan, Kühn, Michael W. M., Paschka, Peter, Kayser, Sabine, Wolf, Stephan, Gaidzik, Verena I., Schlenk, Richard F., Rücker, Frank G., Döhner, Hartmut, Lottaz, Claudio, Döhner, Konstanze und Bullinger, Lars (2012) Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing. Blood 120 (18), e83-e92. Volltext nicht vorhanden.

Beier, Christoph P., Kumar, Praveen, Meyer, Katharina, Leukel, Petra, Bruttel, Valentin, Aschenbrenner, Ines, Riemenschneider, Markus J., Fragoulis, Athanassios, Rümmele, Petra, Lamszus, Katrin, Schulz, Jörg B., Weis, Joachim, Bogdahn, Ulrich, Wischhusen, Jörg, Hau, Peter, Spang, Rainer und Beier, Dagmar (2012) The cancer stem cell subtype determines immune infiltration of glioblastoma. Stem Cells and Development 21 (15), S. 2753-2761. Volltext nicht vorhanden.

Schrader, Alexandra, Bentink, Stefan, Spang, Rainer, Lenze, Dido, Hummel, Michael, Kuo, Michael, Arrand, John R, Murray, Paul G, Trümper, Lorenz, Kube, Dieter und Vockerodt, Martina (2012) High Myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas. International journal of cancer 131 (4), E348-E361. Volltext nicht vorhanden.

Odoardi, Francesca, Sie, Christopher, Streyl, Kristina, Ulaganathan, Vijay K, Schläger, Christian, Lodygin, Dmitri, Heckelsmiller, Klaus, Nietfeld, Wilfried, Ellwart, Joachim, Klinkert, Wolfgang E F, Lottaz, Claudio, Nosov, Mikhail, Brinkmann, Volker, Spang, Rainer, Lehrach, Hans, Vingron, Martin, Wekerle, Hartmut, Flügel-Koch, Cassandra und Flügel, Alexander (2012) T cells become licensed in the lung to enter the central nervous system. Nature 488 (7413), S. 675-679. Volltext nicht vorhanden.

Hertwig, Falk, Meyer, Katharina, Braun, Sebastian, Ek, Sara, Spang, Rainer, Pfenninger, Cosima V., Artner, Isabella, Prost, Gaëlle, Chen, Xinbin, Biegel, Jaclyn A., Judkins, Alexander R., Englund, Elisabet und Nuber, Ulrike A. (2012) Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells. Cancer research 72 (13), S. 3381-3392. Volltext nicht vorhanden.

Kohl, Stefanie M., Klein, Matthias S., Hochrein, Jochen, Oefner, Peter J., Spang, Rainer und Gronwald, Wolfram (2012) State-of-the art data normalization methods improve NMR-based metabolomic analysis. Metabolomics 8 (Suppl), S. 146-160. Volltext nicht vorhanden.

Mulaw, M. A., Krause, A., Krause, A. J., Deshpande, A. J., Krause, L. F., Rouhi, A., La Starza, R., Borkhardt, A., Buske, C., Mecucci, C., Ludwig, W.-D., Lottaz, Claudio und Bohlander, S. K. (2012) CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12. Leukemia 26 (5), S. 1012-1019. Volltext nicht vorhanden.

Klapper, Wolfram, Kreuz, Markus, Kohler, Christian, Burkhardt, Birgit, Szczepanowski, Monika, Salaverria, Itziar, Hummel, Michael, Loeffler, Markus, Pellissery, Shoji, Woessmann, Wilhelm, Schwänen, Carsten, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Hasenclever, Dirk und Siebert, Reiner (2012) Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma. Blood 119 (8), S. 1882-1887. Volltext nicht vorhanden.

Engelmann, Julia C. und Spang, Rainer (2012) A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions. PloS ONE 7 (7), e40634.

Förster, Frank, Beisser, Daniela, Grohme, Markus A, Liang, Chunguang, Mali, Brahim, Siegl, Alexander Matthias, Engelmann, Julia C., Shkumatov, Alexander V, Schokraie, Elham, Müller, Tobias, Schnölzer, Martina, Schill, Ralph O, Frohme, Marcus und Dandekar, Thomas (2012) Transcriptome analysis in tardigrade species reveals specific molecular pathways for stress adaptations. Bioinformatics and biology insights 6, S. 69-96.

2011

Almstetter, Martin F., Appel, Inka, Dettmer, Katja, Gruber, Michael und Oefner, Peter J. (2011) Comparison of two algorithmic data processing strategies for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Journal of chromatography A 1218 (39), S. 7031-7038. Volltext nicht vorhanden.

Appel, Inka, Gronwald, Wolfram und Spang, Rainer (2011) Estimating classification probabilities in high-dimensional diagnostic studies. Bioinformatics 27 (18), S. 2563-2570. Volltext nicht vorhanden.

Maneck, Matthias, Schrader, Alexandra, Kube, Dieter und Spang, Rainer (2011) Genomic data integration using guided clustering. Bioinformatics 27 (16), S. 2231-2238. Volltext nicht vorhanden.

Salaverria, Itziar, Philipp, Claudia, Oschlies, Ilske, Kohler, Christian, Kreuz, Markus, Szczepanowski, Monika, Burkhardt, Birgit, Trautmann, Heiko, Gesk, Stefan, Andrusiewicz, Miroslaw, Berger, Hilmar, Fey, Miriam, Harder, Lana, Hasenclever, Dirk, Hummel, Michael, Loeffler, Markus, Mahn, Friederike, Martin-Guerrero, Idoia, Pellissery, Shoji, Pott, Christiane, Pfreundschuh, Michael, Reiter, Alfred, Richter, Julia, Rosolowski, Maciej, Schwaenen, Carsten, Stein, Harald, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Küppers, Ralf, Klapper, Wolfram und Siebert, Reiner (2011) Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults. Blood 118 (1), S. 139-147. Volltext nicht vorhanden.

VerMilyea, Matthew, Maneck, Matthias, Yoshida, Naoko, Blochberger, Isabell, Suzuki, Emi, Suzuki, Toru, Spang, Rainer, Klein, Christoph A. und Perry, Anthony C. F. (2011) Transcriptome asymmetry within mouse zygotes but not between early embryonic sister blastomeres. The EMBO journal 30 (9), S. 1841-1851. Volltext nicht vorhanden.

Seitz, Volkhard, Butzhammer, Peter, Hirsch, Burkhard, Hecht, Jochen, Gütgemann, Ines, Ehlers, Anke, Lenze, Dido, Oker, Elisabeth, Sommerfeld, Anke, von der Wall, Edda, König, Christoph, Zinser, Christian, Spang, Rainer und Hummel, Michael (2011) Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma. PLoS One 6 (11), e26837.

Lang, Elmar, Schachtner, R., Lutter, D., Herold, Daniela, Kodewitz, A., Blöchl, FJ and Keck, Theis, Fabian J., Keck, Ingo R., Gorriz, J. M., Gomez-Vilda, P. und Tome, A. M. (2011) Exploratory Matrix Factorization Techniques for Large Scale Biomedical Data Sets. In: Nicht ausgewählt Bentham Science Publishers, Hilversum, S. 26-47. ISBN 978-1-60805-218-9. Volltext nicht vorhanden.

2010

Scholtysik, René, Kreuz, Markus, Klapper, Wolfram, Burkhardt, Birgit, Feller, Alfred, Hummel, Michael, Loeffler, Markus, Rosolowski, Maciej, Schwaenen, Carsten, Spang, Rainer, Stein, Harald, Thorns, Christoph, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Zenz, Thorsten, Siebert, Reiner und Küppers, Ralf (2010) Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis. Haematologica 95 (12), S. 2047-2055.

Dettmer, Katja, Almstetter, Martin F., Appel, Inka, Nürnberger, Nadine, Schlamberger, Gregor, Gronwald, Wolfram, Meyer, Heinrich H. D. und Oefner, Peter J. (2010) Comparison of serum versus plasma collection in gas chromatography--mass spectrometry-based metabolomics. Electrophoresis 31 (14), S. 2365-2373. Volltext nicht vorhanden.

Hundsrucker, Christian, Skroblin, Philipp, Christian, Frank, Zenn, Hans-Michael, Popara, Viola, Joshi, Mangesh, Eichhorst, Jenny, Wiesner, Burkhard, Herberg, Friedrich W, Reif, Bernd, Rosenthal, Walter und Klussmann, Enno (2010) Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein. The Journal of biological chemistry 285 (8), S. 5507-5521. Volltext nicht vorhanden.

Neusser, Matthias A., Lindenmeyer, Maja T., Moll, Anton G., Segerer, Stephan, Edenhofer, Ilka, Sen, Kontheari, Stiehl, Daniel P., Kretzler, Matthias, Gröne, Hermann-Josef, Schlöndorff, Detlef und Cohen, Clemens D. (2010) Human nephrosclerosis triggers a hypoxia-related glomerulopathy. The American journal of pathology 176 (2), S. 594-607. Volltext nicht vorhanden.

Ingersoll, Molly A., Spanbroek, Rainer, Lottaz, Claudio, Gautier, Emmanuel L., Frankenberger, Marion, Hoffmann, Reinhard, Lang, Roland, Haniffa, Muzlifah, Collin, Matthew, Tacke, Frank, Habenicht, Andreas .J R., Ziegler-Heitbrock, Loems und Randolph, Gwendalyn J. (2010) Comparison of gene expression profiles between human and mouse monocyte subsets. Blood 115 (3), e10-e19. Volltext nicht vorhanden.

Lottaz, Claudio, Beier, Dagmar, Meyer, Katharina, Kumar, Praveen, Hermann, Andreas, Schwarz, Johannes, Junker, Markus, Oefner, Peter J., Bogdahn, Ulrich, Wischhusen, J, Spang, Rainer, Storch, Alexander und Beier, Christoph P. (2010) Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer research 70 (5), S. 2030-2040. Volltext nicht vorhanden.

2009

Thieme, Marian, Lottaz, Claudio, Niederstätter, Harald, Parson, Walther, Spang, Rainer und Oefner, Peter J. (2009) ReseqChip: automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly. BMC bioinformatics 10, S. 440.

Geue, Lutz, Klare, Sabrina, Schnick, Christina, Mintel, Birgit, Meyer, Katharina und Conraths, Franz J. (2009) Analysis of the clonal relationship of serotype O26:H11 enterohemorrhagic Escherichia coli isolates from cattle. Applied and environmental microbiology 75 (21), S. 6947-6953. Volltext nicht vorhanden.

Förster, Frank, Liang, Chunguang, Shkumatov, Alexander V., Beisser, Daniela, Engelmann, Julia C., Schnölzer, Martina, Frohme, Marcus, Müller, Tobias, Schill, Ralph O. und Dandekar, Thomas (2009) Tardigrade workbench: comparing stress-related proteins, sequence-similar and functional protein clusters as well as RNA elements in tardigrades. BMC genomics 10, S. 469.

Lee, Chil-Woo, Efetova, Marina, Engelmann, Julia C., Kramell, Robert, Wasternack, Claus, Ludwig-Müller, Jutta, Hedrich, Rainer und Deeken, Rosalia (2009) Agrobacterium tumefaciens promotes tumor induction by modulating pathogen defense in Arabidopsis thaliana. The Plant cell 21 (9), S. 2948-2962. Volltext nicht vorhanden.

Lyck, Ruth, Ruderisch, Nadine, Moll, Anton G., Steiner, Oliver, Cohen, Clemens D., Engelhardt, Britta, Makrides, Victoria und Verrey, Francois (2009) Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 29 (9), S. 1491-1502. Volltext nicht vorhanden.

Allam, Ramanjaneyulu, Lichtnekert, Julia, Moll, Anton G., Taubitz, Anela, Vielhauer, Volker und Anders, Hans-Joachim (2009) Viral RNA and DNA trigger common antiviral responses in mesangial cells. Journal of the American Society of Nephrology : JASN 20 (9), S. 1986-1996. Volltext nicht vorhanden.

Eberhart, K., Renner, Kathrin, Ritter, I., Kastenberger, M., Singer, K., Hellerbrand, Claus, Kreutz, Marina, Kofler, R. und Oefner, Peter J. (2009) Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis. Leukemia 23 (11), S. 2167-2170. Volltext nicht vorhanden.

Almstetter, Martin F., Appel, Inka, Gruber, Michael, Lottaz, Claudio, Timischl, Birgit, Spang, Rainer, Dettmer, Katja und Oefner, Peter J. (2009) Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Analytical chemistry 81 (14), S. 5731-5739. Volltext nicht vorhanden.

Vlad, Marcel O., Corlan, Alexandru D., Morán, Federico, Spang, Rainer, Oefner, Peter J. und Ross, John (2009) Kinetic laws, phase-phase expansions, renormalization group, and INR calibration. Proceedings of the National Academy of Sciences of the United States of America 106 (16), S. 6465-6470. Volltext nicht vorhanden.

Anchang, Benedict Nchang, Sadeh, Mohammad Javad, Jacob, Juby, Tresch, Achim, Vlad, Marcel O., Oefner, Peter J. und Spang, Rainer (2009) Modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models. Proceedings of the National Academy of Sciences of the United States of America 106 (16), S. 6447-6452. Volltext nicht vorhanden.

Martín-Subero, José I., Kreuz, Markus, Bibikova, Marina, Bentink, Stefan, Ammerpohl, Ole, Wickham-Garcia, Eliza, Rosolowski, Maciej, Richter, Julia, Lopez-Serra, Lidia, Ballestar, Esteban, Berger, Hilmar, Agirre, Xabier, Bernd, Heinz-Wolfram, Calvanese, Vincenzo, Cogliatti, Sergio B., Drexler, Hans G., Fan, Jian-Bing, Fraga, Mario F., Hansmann, Martin L., Hummel, Michael, Klapper, Wolfram, Korn, Bernhard, Küppers, Ralf, Macleod, Roderick A. F., Möller, Peter, Ott, German, Pott, Christiane, Prosper, Felipe, Rosenwald, Andreas, Schwaenen, Carsten, Schübeler, Dirk, Seifert, Marc, Stürzenhofecker, Benjamin, Weber, Michael, Wessendorf, Swen, Loeffler, Markus, Trümper, Lorenz, Stein, Harald, Spang, Rainer, Esteller, Manel, Barker, David, Hasenclever, Dirk und Siebert, Reiner (2009) New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood 113 (11), S. 2488-2497. Volltext nicht vorhanden.

Schwaenen, Carsten, Viardot, Andreas, Berger, Hilmar, Barth, Thomas F. E., Bentink, Stefa, Döhner, Hartmut, Enz, Martina, Feller, Alfred C., Hansmann, Martin-Leo, Hummel, Michael, Kestler, Hans A, Klapper, Wolfram, Kreuz, Markus, Lenze, Dido, Loeffler, Markus, Möller, Peter, Müller-Hermelink, Hans-Konrad, Ott, German, Rosolowski, Maciej, Rosenwald, Andreas, Ruf, Sandra, Siebert, Reiner, Spang, Rainer, Stein, Harald, Truemper, Lorenz, Lichter, Peter, Bentz, Martin und Wessendorf, Swen (2009) Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status. Genes, Chromosomes and Cancer 48 (1), S. 39-54. Volltext nicht vorhanden.

Engelmann, Julia C., Rahmann, Sven, Wolf, Matthias, Schultz, Jörg, Fritzilas, Epameinondas, Kneitz, Susanne, Dandekar, Thomas und Müller, Tobias (2009) Modelling cross-hybridization on phylogenetic DNA microarrays increases the detection power of closely related species. Molecular ecology resources 9 (1), S. 83-93. Volltext nicht vorhanden.

Moll, Anton G., Lindenmeyer, Maja T., Kretzler, Matthias, Nelson, Peter J., Zimmer, Ralf und Cohen, Clemens D. (2009) Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays. PloS ONE 4 (3), e4702.

2008

Fröhlich, H., Beissbarth, T., Tresch, A., Kostka, D., Jacob, Juby, Spang, Rainer und Markowetz, F. (2008) Analyzing gene perturbation screens with nested effects models in R and bioconductor. Bioinformatics 24 (21), S. 2549-2550. Volltext nicht vorhanden.

Engelmann, Julia C., Deeken, R., Muller, T., Nimtz, G., Roelfsema, M. R. und Hedrich, R. (2008) Is gene activity in plant cells affected by UMTS-irradiation? A whole genome approach. Advances and Applications in Bioinformatics and Chemistry (Adv Appl Bioinform Chem) 1, S. 71-83.

Bentink, Stefan, Wessendorf, S., Schwaenen, C., Rosolowski, M., Klapper, W., Rosenwald, A., Ott, G., Banham, A. H., Berger, H., Feller, A. C., Hansmann, M. L., Hasenclever, D., Hummel, M., Lenze, D., Möller, P., Stuerzenhofecker, B., Loeffler, M., Truemper, L., Stein, H., Siebert, R. und Spang, Rainer (2008) Pathway activation patterns in diffuse large B-cell lymphomas. Leukemia 22 (9), S. 1746-1754. Volltext nicht vorhanden.

Klapper, W., Szczepanowski, M., Burkhardt, B., Berger, H., Rosolowski, M., Bentink, Stefan, Schwaenen, C., Wessendorf, S., Spang, Rainer, Moller, P., Hansmann, M. L., Bernd, H. W., Ott, G., Hummel, M., Stein, H., Loeffler, M., Trumper, L., Zimmermann, M., Reiter, A. und Siebert, R. (2008) Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. Blood 112 (4), S. 1374-1381. Volltext nicht vorhanden.

Cohen, C. D., Lindenmeyer, M. T., Eichinger, F., Hahn, A., Seifert, M., Moll, Anton G., Schmid, H., Kiss, E., Grone, E., Grone, H. J., Kretzler, M., Werner, T. und Nelson, P. J. (2008) Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis. PLoS ONE 3 (8), e2937.

Dohm, Juliane C., Lottaz, Claudio, Borodina, Tatiana und Himmelbauer, Heinz (2008) Substantial biases in ultra-short read data sets from high-throughput DNA sequencing. Nucleic Acids Research 36 (16), e105.

Dierlamm, J., Murga Penas, E. M., Bentink, Stefan, Wessendorf, S., Berger, H., Hummel, M., Klapper, W., Lenze, D., Rosenwald, A., Haralambieva, E., Ott, G., Cogliatti, S. B., Möller, Peter, Schwaenen, C., Stein, H., Löffler, M., Spang, Rainer, Trumper, L. und Siebert, Reiner (2008) Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. Haematologica 93 (5), S. 688-696.

Jacob, Juby, Jentsch, M., Kostka, Dennis, Bentink, Stefan und Spang, Rainer (2008) Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs. Bioinformatics 24 (7), S. 995-1001. Volltext nicht vorhanden.

Blenk, Steffen, Engelmann, Julia C., Pinkert, Stefan, Weniger, Markus, Schultz, Jörg, Rosenwald, Andreas, Müller-Hermelink, Hans K, Müller, Tobias und Dandekar, Thomas (2008) Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC cancer 8, S. 106.

Lottaz, Claudio, Kostka, Dennis und Spang, Rainer (2008) 26. Classification of Patients. In: Lengauer, Thomas, (ed.) Bioinformatics-From Genomes to Therapies. Wiley-VCH, Weinheim, S. 957-991. ISBN 9783527619368 (online). Volltext nicht vorhanden.

Montesinos-Rongen, M,, Brunn, A,, Bentink, Stefan, Basso, K,, Lim, W, K,, Klapper, Wolfram, Schaller, C,, Reifenberger, G,, Rubenstein, J,, Wiestler, O, D,, Spang, Rainer, Dalla-Favera, R,, Siebert, Reiner und Deckert, M, (2008) Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell. Leukemia 22 (2), S. 400-405. Volltext nicht vorhanden.

Kostka, Dennis und Spang, Rainer (2008) Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures. PLoS Computational Biology 4 (2), e22.

Lottaz, Claudio, Kostka, Dennis, Markowetz, Florian und Spang, Rainer (2008) 15. Computational diagnostics with gene expression profiles. In: Bioinformatics. Methods in Molecular Biology, 453 (15). Humana Press, Totowa, NJ, S. 281-296. ISBN 978-1-60327-428-9. Volltext nicht vorhanden.

2007

Blenk, S., Engelmann, Julia C., Weniger, M., Schultz, J., Dittrich, M., Rosenwald, A., Muller-Hermelink, H. K., Müller, T. und Dandekar, T. (2007) Germinal center B cell-like (GCB) and activated B cell-like (ABC) type of diffuse large B cell lymphoma (DLBCL): analysis of molecular predictors, signatures, cell cycle state and patient survival. Cancer Informatics 3, S. 399-420.

Roesch, Alexander, Becker, Bernd, Bentink, Stefan, Spang, Rainer, Vogl, Annegret, Hagen, Ilja, Landthaler, Michael und Vogt, Thomas (2007) Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Prevention 16 (11), S. 2486-2490. Volltext nicht vorhanden.

Hoffmann, Reinhard, Lottaz, Claudio, Kühne, Thomas, Rolink, Antonius und Melchers, Fritz (2007) Neutrality, compensation, and negative selection during evolution of B-cell development transcriptomes. Molecular Biology and Evolution (Mol Biol Evol) 24 (12), S. 2610-2618. Volltext nicht vorhanden.

Lottaz, Claudio, Toedling, Joern und Spang, Rainer (2007) Annotation-based distance measures for patient subgroup discovery in clinical microarray studies. Bioinformatics 23 (17), S. 2256-2264. Volltext nicht vorhanden.

Markowetz, Florian und Spang, Rainer (2007) Inferring cellular networks - a review. BMC bioinformatics 8 Suppl 6, S5.

Dohm, Juliane C., Lottaz, Claudio, Borodina, Tatiana und Himmelbauer, Heinz (2007) SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing. Genome Research 17 (11), S. 1697-1706. Volltext nicht vorhanden.

Bullinger, Lars, Rücker, Frank G., Kurz, Stephan, Du, Juan, Scholl, Claudia, Sander, Sandrine, Corbacioglu, Andrea, Lottaz, Claudio, Krauter, Jürgen, Fröhling, Stefan, Ganser, Arnold, Schlenk, Richard F., Döhner, Konstanze, Pollack, Jonathan R. und Döhner, Hartmut (2007) Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia. Blood 110 (4), S. 1291-1300. Volltext nicht vorhanden.

Weniger, M., Engelmann, Julia C. und Schultz, J. (2007) Genome Expression Pathway Analysis Tool--analysis and visualization of microarray gene expression data under genomic, proteomic and metabolic context. BMC Bioinformatics 8, S. 179.

Rhein, P., Scheid, S., Ratei, R., Hagemeier, C., Seeger, K., Kirschner-Schwabe, R., Moericke, A., Schrappe, M., Spang, Rainer, Ludwig, W.-D. und Karawajew, L. (2007) Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia. Leukemia 21 (5), S. 897-905. Volltext nicht vorhanden.

Jaeger, Jochen, Koczan, Dirk, Thiesen, Hans-Juergen, Ibrahim, Saleh M., Gross, Gerd, Spang, Rainer und Kunz, Manfred (2007) Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues. Clinical cancer research 13 (3), S. 806-815. Volltext nicht vorhanden.

2006

Jaeger, J. und Spang, Rainer (2006) Selecting normalization genes for small diagnostic microarrays. BMC Bioinformatics 7, S. 388.

Kirschner-Schwabe, R., Lottaz, Claudio, Todling, J., Rhein, P., Karawajew, L., Eckert, C., von Stackelberg, A., Ungethum, U., Kostka, Dennis, Kulozik, A. E., Ludwig, W. D., Henze, G., Spang, Rainer, Hagemeier, C. und Seeger, K. (2006) Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia. Clinical Cancer Research 12 (15), S. 4553-4561. Volltext nicht vorhanden.

Lottaz, Claudio, Yang, Xinan, Scheid, Stefanie und Spang, Rainer (2006) OrderedList - a bioconductor package for detecting similarity in ordered gene lists. Bioinformatics 22 (18), S. 2315-2316. Volltext nicht vorhanden.

Hummel, M., Bentink, S., Berger, H., Klapper, W., Wessendorf, S., Barth, T. F., Bernd, H. W., Cogliatti, S. B., Dierlamm, J., Feller, A. C. und Spang, Rainer (2006) A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. New England Journal of Medicine 354 (23), S. 2419-2430. Volltext nicht vorhanden.

Toedling, J., Rhein, P., Ratei, R., Karawajew, L. und Spang, Rainer (2006) Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring. BMC Bioinformatics 7, S. 282.

2005

Markowetz, F., Bloch, J. und Spang, Rainer (2005) Non-transcriptional pathway features reconstructed from secondary effects of RNA interference. Bioinformatics 21 (21), S. 4026-4032. Volltext nicht vorhanden.

Yang, X., Bentink, Stefan und Spang, Rainer (2005) Detecting common gene expression patterns in multiple cancer outcome entities. Biomedical Microdevices 7 (3), S. 247-251. Volltext nicht vorhanden.

Lottaz, Claudio und Spang, Rainer (2005) stam – a Bioconductor compliant R package for structured analysis of microarray data. BMC Bioinformatics 6, S. 211.

Scheid, S. und Spang, Rainer (2005) twilight; a Bioconductor package for estimating the local false discovery rate. Bioinformatics 21 (12), S. 2921-2922. Volltext nicht vorhanden.

Jaeger, J., Weichenhan, D., Ivandic, B. und Spang, Rainer (2005) Early diagnostic marker panel determination for microarray based clinical studies. Statistical Applications in Genetics and Molecular Biology 4 (1), article 9. Volltext nicht vorhanden.

Lottaz, Claudio und Spang, Rainer (2005) Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data. Bioinformatics 21 (9), S. 1971-1978.

Lottaz, Claudio, Kostka, Dennis, Markowetz, Florian und Spang, Rainer (2005) Traces of molecular disease mechanisms on microarrays. Methods in Molecular Biology 453, S. 281-296. Volltext nicht vorhanden.

2004

Kostka, Dennis und Spang, Rainer (2004) Finding disease specific alterations in the co-expression of genes. Bioinformatics 20 Suppl 1, i194-i199. Volltext nicht vorhanden.

Scheid, Stefanie und Spang, Rainer (2004) A stochastic downhill search algorithm for estimating the local false discovery rate. IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB 1 (3), S. 98-108. Volltext nicht vorhanden.

2003

Blaxall, B. C., Spang, Rainer, Rockman, H. A. und Koch, W. J. (2003) Differential myocardial gene expression in the development and rescue of murine heart failure. Physiological Genomics 15 (2), S. 105-114. Volltext nicht vorhanden.

Lottaz, C., Iseli, C., Jongeneel, C. V. und Bucher, P. (2003) Modeling sequencing errors by combining Hidden Markov models. Bioinformatics 19 (Suppl2), ii103-ii112.

Grzeskowiak, R., Witt, Henning, Drungowski, M., Thermann, R., Hennig, S., Perrot, A., Osterziel, K., Klingbiel, D., Scheid, Stefanie und Spang, Rainer (2003) Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovascular Research 59, S. 400-411. Volltext nicht vorhanden.

2002

Muller, Tobias, Spang, Rainer und Vingron, M. (2002) Estimating amino acid substitution models: a comparison of Dayhoff's estimator, the resolvent approach and a maximum likelihood method. Molecular Biology and Evolution 19 (1), S. 8-13. Volltext nicht vorhanden.

Spang, Rainer, Rehmsmeier, M. und Stoye, J. (2002) A novel approach to remote homology detection: jumping alignments. Journal of Computational Biology 9 (5), S. 747-760. Volltext nicht vorhanden.

Spang, Rainer, Zuzan, H., West, M., Nevins, J., Blanchette, C. und Marks, J. R. (2002) Prediction and uncertainty in the analysis of gene expression profiles. In Silico Biology 2 (3), S. 369-381. Volltext nicht vorhanden.

Diese Liste wurde erzeugt am Mon Aug 20 12:21:15 2018 CEST.
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