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Generation of Highly Purified Human Cardiomyocytes from Peripheral Blood Mononuclear Cell-Derived Induced Pluripotent Stem Cells

Zimmermann, Martina E., Fuerstenau-Sharp, Maya, Stark, Klaus, Jentsch, Nico, Klingenstein, Melanie, Drzymalski, Marzena, Wagner, Stefan, Maier, Lars S., Baessler, Andrea, Fischer, Marcus, Hengstenberg, Christian and Hehr, Ute (2015) Generation of Highly Purified Human Cardiomyocytes from Peripheral Blood Mononuclear Cell-Derived Induced Pluripotent Stem Cells. PLoS ONE 10 (5), pp. 1-21.

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Date of publication of this fulltext: 18 Jun 2015 15:43

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126596


Abstract

Induced pluripotent stem (iPS) cells have an enormous potential for physiological studies. A novel protocol was developed combining the derivation of iPS from peripheral blood with an optimized directed differentiation to cardiomyocytes and a subsequent metabolic selection. The human iPS cells were retrovirally dedifferentiated from activated T cells. The subsequent optimized directed ...

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Item type:Article
Date:13 May 2015
Institutions:Medicine > Institut für Epidemiologie und Präventivmedizin
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0126596DOI
Article ID: e0126596Other
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31972
Owner only: item control page

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