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Characterization of CAMTA1 and Nkx2.2 in the context of glioblastoma cancer stem cell biology

Wankerl, Ludwig (2016) Characterization of CAMTA1 and Nkx2.2 in the context of glioblastoma cancer stem cell biology. PhD, Universität Regensburg.

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Date of publication of this fulltext: 09 Feb 2016 06:02

Abstract (English)

Glioblastoma multiforme (glioblastoma) is the most malignant type of tumor in the human brain. For glioblastomas and several other cancer types, the existence of so called "cancer stem cells" was described. Cancer stem cells are characterized by stem cell-like traits such as the capacity of self-renewal and differentiation. Moreover, there is evidence that these cells contribute to cancer ...

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Translation of the abstract (German)

Glioblastoma multiforme (Glioblastom) ist eine Tumorform, die im Gehirn auftritt und unter den Gehirntumoren den höchsten Grad an Malignität aufweist. Für Glioblastome und diverse andere Krebsarten wurde die Existenz von sog. "Krebs-Stammzellen" nachgewiesen. Krebs-Stammzellen zeichnen sich durch ähnliche Charakteristika aus wie Stammzellen von normalem, gesundem Gewebe, d.h. sie sind fähig, sich ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:9 February 2016
Referee:Prof. Dr. Gunter Meister
Date of exam:28 January 2016
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister
Keywords:Cancer stem cells, CAMTA1, Nkx2.2, glioblastoma, tumor suppressor
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33258
Owner only: item control page

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